The current clinical management of Huntington's disease.
Identifieur interne : 002189 ( Ncbi/Curation ); précédent : 002188; suivant : 002190The current clinical management of Huntington's disease.
Auteurs : Wendy Phillips [Royaume-Uni] ; Kathleen M. Shannon ; Roger A. BarkerSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2008.
English descriptors
- KwdEn :
- Cognition Disorders (drug therapy), Cognition Disorders (etiology), Diagnosis, Differential, Genetic Counseling, Humans, Huntington Disease (complications), Huntington Disease (therapy), Mental Disorders (drug therapy), Mental Disorders (etiology), Movement Disorders (drug therapy), Movement Disorders (etiology), Palliative Care.
- MESH :
- complications : Huntington Disease.
- drug therapy : Cognition Disorders, Mental Disorders, Movement Disorders.
- etiology : Cognition Disorders, Mental Disorders, Movement Disorders.
- therapy : Huntington Disease.
- Diagnosis, Differential, Genetic Counseling, Humans, Palliative Care.
Abstract
Huntington's disease is a neurodegenerative condition, characterized by movement disorders, cognitive decline, and psychiatric disturbance. We review the pharmacological management of the various movement disorders associated with the disease, the cognitive decline and the commonly encountered behavioral disturbances. We discuss the nonclassical features of the disease, important in the management of these patients. Nonpharmacological support including genetic counseling and therapy and the importance of palliative care are also addressed. Finally, experimental approaches that may soon impact upon clinical practice are discussed.
DOI: 10.1002/mds.21971
PubMed: 18581443
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