Role of attentional resources on gait performance in Huntington's disease.
Identifieur interne : 002008 ( Ncbi/Curation ); précédent : 002007; suivant : 002009Role of attentional resources on gait performance in Huntington's disease.
Auteurs : Arnaud Delval [France] ; Pierre Krystkowiak ; Marie Delliaux ; Kathy Dujardin ; Jean-Louis Blatt ; Alain Destée [France] ; Philippe Derambure ; Luc Defebvre [France]Source :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2008.
English descriptors
- KwdEn :
- MESH :
- complications : Huntington Disease.
- etiology : Gait Disorders, Neurologic.
- physiopathology : Gait Disorders, Neurologic, Huntington Disease.
- Adult, Attention, Biomechanical Phenomena, Humans, Middle Aged, Motor Activity, Neuropsychological Tests, Time Factors.
Abstract
Patients with Huntington's disease (HD) suffer from cognitive deficits with impaired executive functions, including limited attentional resources. We sought to use a dual-task paradigm to evaluate attentional demands and the ability of patients with HD to concentrate on two tasks simultaneously. We analyzed the interference effects of cognitive and motor tasks on walking in HD and the contribution of clinical symptoms to gait disturbances. Patients and controls were asked to perform either a motor task (carrying a tray with four glasses), a cognitive task (counting backwards), or no task at all while walking at their preferred speed. Kinematic spatial parameters, temporal parameters, and angular parameters related to gait were recorded in 15 patients and 15 controls by means of a videomotion analysis system. Gait instability was assessed using the stride-to-stride variability of the various gait parameters. For patients with HD, performing a concurrent cognitive task resulted in a lower gait speed (compared with free walking), with decreased cadence and stride length. However, this effect was not observed in controls. Performing a motor task did not change any kinematic gait parameters in either HD or control subjects. We found correlations between gait speed in the dual cognitive/walking task on one hand and the motor UHDRS score, cognitive status and executive function on the other. Patients with HD had greater difficulty walking while performing a concurrent cognitive task; the drain on attentional resources deteriorated walking performance.
DOI: 10.1002/mds.21896
PubMed: 18175353
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :002351
- to stream PubMed, to step Curation: Pour aller vers cette notice dans l'étape Curation :002351
- to stream PubMed, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :002092
- to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :002008
Links to Exploration step
pubmed:18175353Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Role of attentional resources on gait performance in Huntington's disease.</title>
<author><name sortKey="Delval, Arnaud" sort="Delval, Arnaud" uniqKey="Delval A" first="Arnaud" last="Delval">Arnaud Delval</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology and Movement Disorders, Salengro Hospital, Lille Regional University Hospital, Lille Cedex, France. a-delval@chru-lille.fr</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Neurology and Movement Disorders, Salengro Hospital, Lille Regional University Hospital, Lille Cedex</wicri:regionArea>
<wicri:noRegion>Lille Cedex</wicri:noRegion>
<wicri:noRegion>Lille Cedex</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Krystkowiak, Pierre" sort="Krystkowiak, Pierre" uniqKey="Krystkowiak P" first="Pierre" last="Krystkowiak">Pierre Krystkowiak</name>
</author>
<author><name sortKey="Delliaux, Marie" sort="Delliaux, Marie" uniqKey="Delliaux M" first="Marie" last="Delliaux">Marie Delliaux</name>
</author>
<author><name sortKey="Dujardin, Kathy" sort="Dujardin, Kathy" uniqKey="Dujardin K" first="Kathy" last="Dujardin">Kathy Dujardin</name>
</author>
<author><name sortKey="Blatt, Jean Louis" sort="Blatt, Jean Louis" uniqKey="Blatt J" first="Jean-Louis" last="Blatt">Jean-Louis Blatt</name>
</author>
<author><name sortKey="Destee, Alain" sort="Destee, Alain" uniqKey="Destee A" first="Alain" last="Destée">Alain Destée</name>
<affiliation><country>France</country>
<placeName><settlement type="city">Lille</settlement>
<region type="region" nuts="2">Nord-Pas-de-Calais</region>
</placeName>
<orgName type="university" n="3">Université Lille 2</orgName>
<orgName type="institution" wicri:auto="newGroup">Université Lille Nord de France</orgName>
</affiliation>
</author>
<author><name sortKey="Derambure, Philippe" sort="Derambure, Philippe" uniqKey="Derambure P" first="Philippe" last="Derambure">Philippe Derambure</name>
</author>
<author><name sortKey="Defebvre, Luc" sort="Defebvre, Luc" uniqKey="Defebvre L" first="Luc" last="Defebvre">Luc Defebvre</name>
<affiliation><country>France</country>
<placeName><settlement type="city">Lille</settlement>
<region type="region" nuts="2">Nord-Pas-de-Calais</region>
</placeName>
<orgName type="university" n="3">Université Lille 2</orgName>
<orgName type="institution" wicri:auto="newGroup">Université Lille Nord de France</orgName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2008">2008</date>
<idno type="doi">10.1002/mds.21896</idno>
<idno type="RBID">pubmed:18175353</idno>
<idno type="pmid">18175353</idno>
<idno type="wicri:Area/PubMed/Corpus">002351</idno>
<idno type="wicri:Area/PubMed/Curation">002351</idno>
<idno type="wicri:Area/PubMed/Checkpoint">002092</idno>
<idno type="wicri:Area/Ncbi/Merge">002008</idno>
<idno type="wicri:Area/Ncbi/Curation">002008</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Role of attentional resources on gait performance in Huntington's disease.</title>
<author><name sortKey="Delval, Arnaud" sort="Delval, Arnaud" uniqKey="Delval A" first="Arnaud" last="Delval">Arnaud Delval</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology and Movement Disorders, Salengro Hospital, Lille Regional University Hospital, Lille Cedex, France. a-delval@chru-lille.fr</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Neurology and Movement Disorders, Salengro Hospital, Lille Regional University Hospital, Lille Cedex</wicri:regionArea>
<wicri:noRegion>Lille Cedex</wicri:noRegion>
<wicri:noRegion>Lille Cedex</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Krystkowiak, Pierre" sort="Krystkowiak, Pierre" uniqKey="Krystkowiak P" first="Pierre" last="Krystkowiak">Pierre Krystkowiak</name>
</author>
<author><name sortKey="Delliaux, Marie" sort="Delliaux, Marie" uniqKey="Delliaux M" first="Marie" last="Delliaux">Marie Delliaux</name>
</author>
<author><name sortKey="Dujardin, Kathy" sort="Dujardin, Kathy" uniqKey="Dujardin K" first="Kathy" last="Dujardin">Kathy Dujardin</name>
</author>
<author><name sortKey="Blatt, Jean Louis" sort="Blatt, Jean Louis" uniqKey="Blatt J" first="Jean-Louis" last="Blatt">Jean-Louis Blatt</name>
</author>
<author><name sortKey="Destee, Alain" sort="Destee, Alain" uniqKey="Destee A" first="Alain" last="Destée">Alain Destée</name>
<affiliation><country>France</country>
<placeName><settlement type="city">Lille</settlement>
<region type="region" nuts="2">Nord-Pas-de-Calais</region>
</placeName>
<orgName type="university" n="3">Université Lille 2</orgName>
<orgName type="institution" wicri:auto="newGroup">Université Lille Nord de France</orgName>
</affiliation>
</author>
<author><name sortKey="Derambure, Philippe" sort="Derambure, Philippe" uniqKey="Derambure P" first="Philippe" last="Derambure">Philippe Derambure</name>
</author>
<author><name sortKey="Defebvre, Luc" sort="Defebvre, Luc" uniqKey="Defebvre L" first="Luc" last="Defebvre">Luc Defebvre</name>
<affiliation><country>France</country>
<placeName><settlement type="city">Lille</settlement>
<region type="region" nuts="2">Nord-Pas-de-Calais</region>
</placeName>
<orgName type="university" n="3">Université Lille 2</orgName>
<orgName type="institution" wicri:auto="newGroup">Université Lille Nord de France</orgName>
</affiliation>
</author>
</analytic>
<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
<idno type="eISSN">1531-8257</idno>
<imprint><date when="2008" type="published">2008</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Attention</term>
<term>Biomechanical Phenomena</term>
<term>Gait Disorders, Neurologic (etiology)</term>
<term>Gait Disorders, Neurologic (physiopathology)</term>
<term>Humans</term>
<term>Huntington Disease (complications)</term>
<term>Huntington Disease (physiopathology)</term>
<term>Middle Aged</term>
<term>Motor Activity</term>
<term>Neuropsychological Tests</term>
<term>Time Factors</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Huntington Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Gait Disorders, Neurologic</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Gait Disorders, Neurologic</term>
<term>Huntington Disease</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Attention</term>
<term>Biomechanical Phenomena</term>
<term>Humans</term>
<term>Middle Aged</term>
<term>Motor Activity</term>
<term>Neuropsychological Tests</term>
<term>Time Factors</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Patients with Huntington's disease (HD) suffer from cognitive deficits with impaired executive functions, including limited attentional resources. We sought to use a dual-task paradigm to evaluate attentional demands and the ability of patients with HD to concentrate on two tasks simultaneously. We analyzed the interference effects of cognitive and motor tasks on walking in HD and the contribution of clinical symptoms to gait disturbances. Patients and controls were asked to perform either a motor task (carrying a tray with four glasses), a cognitive task (counting backwards), or no task at all while walking at their preferred speed. Kinematic spatial parameters, temporal parameters, and angular parameters related to gait were recorded in 15 patients and 15 controls by means of a videomotion analysis system. Gait instability was assessed using the stride-to-stride variability of the various gait parameters. For patients with HD, performing a concurrent cognitive task resulted in a lower gait speed (compared with free walking), with decreased cadence and stride length. However, this effect was not observed in controls. Performing a motor task did not change any kinematic gait parameters in either HD or control subjects. We found correlations between gait speed in the dual cognitive/walking task on one hand and the motor UHDRS score, cognitive status and executive function on the other. Patients with HD had greater difficulty walking while performing a concurrent cognitive task; the drain on attentional resources deteriorated walking performance.</div>
</front>
</TEI>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Ncbi/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002008 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd -nk 002008 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Santé |area= MovDisordV3 |flux= Ncbi |étape= Curation |type= RBID |clé= pubmed:18175353 |texte= Role of attentional resources on gait performance in Huntington's disease. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/RBID.i -Sk "pubmed:18175353" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd \ | NlmPubMed2Wicri -a MovDisordV3
This area was generated with Dilib version V0.6.23. |