Clinical and positron emission tomography findings of chorea associated with primary antiphospholipid antibody syndrome.
Identifieur interne : 001D78 ( Ncbi/Curation ); précédent : 001D77; suivant : 001D79Clinical and positron emission tomography findings of chorea associated with primary antiphospholipid antibody syndrome.
Auteurs : Steve W. Wu [États-Unis] ; Brent Graham ; Michael J. Gelfand ; Ralph E. Gruppo ; Argirios Dinopolous ; Donald L. GilbertSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2007.
English descriptors
- KwdEn :
- Adolescent, Attention Deficit Disorder with Hyperactivity (complications), Cardiolipins (immunology), Chorea (etiology), Chorea (immunology), Chorea (radionuclide imaging), Fluorodeoxyglucose F18 (diagnostic use), Humans, Immunoglobulin G (blood), Male, Neurologic Examination, Positron-Emission Tomography (methods), beta 2-Glycoprotein I (immunology).
- MESH :
- chemical , blood : Immunoglobulin G.
- chemical , diagnostic use : Fluorodeoxyglucose F18.
- chemical , immunology : Cardiolipins, beta 2-Glycoprotein I.
- complications : Attention Deficit Disorder with Hyperactivity.
- etiology : Chorea.
- immunology : Chorea.
- methods : Positron-Emission Tomography.
- radionuclide imaging : Chorea.
- Adolescent, Humans, Male, Neurologic Examination.
Abstract
A fourteen-year-old right-handed male with a history of attention deficit hyperactivity disorder (ADHD) presented with alternating hemichorea. Laboratory findings included elevated anticardiolipin IgG and anti-beta(2)-glycoprotein I IgG, which were consistent with primary antiphospholipid antibody syndrome. Positron emission tomography (PET) imaging revealed altered striatal metabolism in his left putamen while he was exhibiting right-sided hemichorea. His symptoms resolved on prednisone; however, his antiphospholipid antibody profile remained markedly abnormal despite being symptom-free for 26 months.
DOI: 10.1002/mds.21657
PubMed: 17659641
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Gelfand</name></author><author><name sortKey="Gruppo, Ralph E" sort="Gruppo, Ralph E" uniqKey="Gruppo R" first="Ralph E" last="Gruppo">Ralph E. Gruppo</name></author><author><name sortKey="Dinopolous, Argirios" sort="Dinopolous, Argirios" uniqKey="Dinopolous A" first="Argirios" last="Dinopolous">Argirios Dinopolous</name></author><author><name sortKey="Gilbert, Donald L" sort="Gilbert, Donald L" uniqKey="Gilbert D" first="Donald L" last="Gilbert">Donald L. Gilbert</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2007">2007</date><idno type="doi">10.1002/mds.21657</idno><idno type="RBID">pubmed:17659641</idno><idno type="pmid">17659641</idno><idno type="wicri:Area/PubMed/Corpus">002581</idno><idno type="wicri:Area/PubMed/Curation">002581</idno><idno type="wicri:Area/PubMed/Checkpoint">002915</idno><idno type="wicri:Area/Ncbi/Merge">001D78</idno><idno type="wicri:Area/Ncbi/Curation">001D78</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Clinical and positron emission tomography findings of chorea associated with primary antiphospholipid antibody syndrome.</title><author><name sortKey="Wu, Steve W" sort="Wu, Steve W" uniqKey="Wu S" first="Steve W" last="Wu">Steve W. Wu</name><affiliation wicri:level="1"><nlm:affiliation>Division of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA. Steve.wu@cchmc.org</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229</wicri:regionArea><wicri:noRegion>Ohio 45229</wicri:noRegion></affiliation></author><author><name sortKey="Graham, Brent" sort="Graham, Brent" uniqKey="Graham B" first="Brent" last="Graham">Brent Graham</name></author><author><name sortKey="Gelfand, Michael J" sort="Gelfand, Michael J" uniqKey="Gelfand M" first="Michael J" last="Gelfand">Michael J. Gelfand</name></author><author><name sortKey="Gruppo, Ralph E" sort="Gruppo, Ralph E" uniqKey="Gruppo R" first="Ralph E" last="Gruppo">Ralph E. Gruppo</name></author><author><name sortKey="Dinopolous, Argirios" sort="Dinopolous, Argirios" uniqKey="Dinopolous A" first="Argirios" last="Dinopolous">Argirios Dinopolous</name></author><author><name sortKey="Gilbert, Donald L" sort="Gilbert, Donald L" uniqKey="Gilbert D" first="Donald L" last="Gilbert">Donald L. Gilbert</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="ISSN">0885-3185</idno><imprint><date when="2007" type="published">2007</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Attention Deficit Disorder with Hyperactivity (complications)</term><term>Cardiolipins (immunology)</term><term>Chorea (etiology)</term><term>Chorea (immunology)</term><term>Chorea (radionuclide imaging)</term><term>Fluorodeoxyglucose F18 (diagnostic use)</term><term>Humans</term><term>Immunoglobulin G (blood)</term><term>Male</term><term>Neurologic Examination</term><term>Positron-Emission Tomography (methods)</term><term>beta 2-Glycoprotein I (immunology)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Immunoglobulin G</term></keywords><keywords scheme="MESH" type="chemical" qualifier="diagnostic use" xml:lang="en"><term>Fluorodeoxyglucose F18</term></keywords><keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>Cardiolipins</term><term>beta 2-Glycoprotein I</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Attention Deficit Disorder with Hyperactivity</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Chorea</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Chorea</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Positron-Emission Tomography</term></keywords><keywords scheme="MESH" qualifier="radionuclide imaging" xml:lang="en"><term>Chorea</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Humans</term><term>Male</term><term>Neurologic Examination</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A fourteen-year-old right-handed male with a history of attention deficit hyperactivity disorder (ADHD) presented with alternating hemichorea. Laboratory findings included elevated anticardiolipin IgG and anti-beta(2)-glycoprotein I IgG, which were consistent with primary antiphospholipid antibody syndrome. Positron emission tomography (PET) imaging revealed altered striatal metabolism in his left putamen while he was exhibiting right-sided hemichorea. His symptoms resolved on prednisone; however, his antiphospholipid antibody profile remained markedly abnormal despite being symptom-free for 26 months.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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