Asymmetrical ventricular enlargement in Parkinson's disease.
Identifieur interne : 001D47 ( Ncbi/Curation ); précédent : 001D46; suivant : 001D48Asymmetrical ventricular enlargement in Parkinson's disease.
Auteurs : Xuemei Huang [Canada] ; Yueh Z. Lee ; Martin Mckeown ; Guido Gerig ; Hongbin Gu ; Weili Lin ; Mechelle M. Lewis ; Sutapa Ford ; Alexander I. Tröster ; Daniel R. Weinberger ; Martin StynerSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2007.
English descriptors
- KwdEn :
- MESH :
Abstract
Parkinson's disease (PD) typically manifests with asymmetric motor symptom onset. Ventricular enlargement, a nonspecific measure of brain atrophy, has been associated with cognitive decline in PD, but not with motor symptom asymmetry. Asymmetrical ventricular enlargement on magnetic resonance images was explored in a monozygotic twin pair discordant for PD and in nine healthy monozygotic twin pairs. The left-right lateral ventricular volumetric difference of the PD-twin was greater than that of his twin and all other healthy twins, with the larger ventricle observed contralateral to the more symptomatic side. Moreover, the lateral ventricle asymmetry difference between twin pairs was significantly higher for the discordant PD-twin pair than for the healthy twin pairs. This is the first report to suggest the presence of asymmetrical ventricular enlargement in PD, findings that may be worthy of further study.
DOI: 10.1002/mds.21626
PubMed: 17588238
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :002612
- to stream PubMed, to step Curation: Pour aller vers cette notice dans l'étape Curation :002612
- to stream PubMed, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :002963
- to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :001D47
Links to Exploration step
pubmed:17588238Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Asymmetrical ventricular enlargement in Parkinson's disease.</title><author><name sortKey="Huang, Xuemei" sort="Huang, Xuemei" uniqKey="Huang X" first="Xuemei" last="Huang">Xuemei Huang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, School of Medicine, University of North Carolina, Chapel Hill, North Carolina 27599-7025, USA, and University Hospital, Vancouver, British Columbia, Canada. xuemei@med.unc.edu</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Neurology, School of Medicine, University of North Carolina, Chapel Hill, North Carolina 27599-7025, USA, and University Hospital, Vancouver, British Columbia</wicri:regionArea><wicri:noRegion>British Columbia</wicri:noRegion></affiliation></author><author><name sortKey="Lee, Yueh Z" sort="Lee, Yueh Z" uniqKey="Lee Y" first="Yueh Z" last="Lee">Yueh Z. Lee</name></author><author><name sortKey="Mckeown, Martin" sort="Mckeown, Martin" uniqKey="Mckeown M" first="Martin" last="Mckeown">Martin Mckeown</name></author><author><name sortKey="Gerig, Guido" sort="Gerig, Guido" uniqKey="Gerig G" first="Guido" last="Gerig">Guido Gerig</name></author><author><name sortKey="Gu, Hongbin" sort="Gu, Hongbin" uniqKey="Gu H" first="Hongbin" last="Gu">Hongbin Gu</name></author><author><name sortKey="Lin, Weili" sort="Lin, Weili" uniqKey="Lin W" first="Weili" last="Lin">Weili Lin</name></author><author><name sortKey="Lewis, Mechelle M" sort="Lewis, Mechelle M" uniqKey="Lewis M" first="Mechelle M" last="Lewis">Mechelle M. Lewis</name></author><author><name sortKey="Ford, Sutapa" sort="Ford, Sutapa" uniqKey="Ford S" first="Sutapa" last="Ford">Sutapa Ford</name></author><author><name sortKey="Troster, Alexander I" sort="Troster, Alexander I" uniqKey="Troster A" first="Alexander I" last="Tröster">Alexander I. Tröster</name></author><author><name sortKey="Weinberger, Daniel R" sort="Weinberger, Daniel R" uniqKey="Weinberger D" first="Daniel R" last="Weinberger">Daniel R. Weinberger</name></author><author><name sortKey="Styner, Martin" sort="Styner, Martin" uniqKey="Styner M" first="Martin" last="Styner">Martin Styner</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2007">2007</date><idno type="doi">10.1002/mds.21626</idno><idno type="RBID">pubmed:17588238</idno><idno type="pmid">17588238</idno><idno type="wicri:Area/PubMed/Corpus">002612</idno><idno type="wicri:Area/PubMed/Curation">002612</idno><idno type="wicri:Area/PubMed/Checkpoint">002963</idno><idno type="wicri:Area/Ncbi/Merge">001D47</idno><idno type="wicri:Area/Ncbi/Curation">001D47</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Asymmetrical ventricular enlargement in Parkinson's disease.</title><author><name sortKey="Huang, Xuemei" sort="Huang, Xuemei" uniqKey="Huang X" first="Xuemei" last="Huang">Xuemei Huang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, School of Medicine, University of North Carolina, Chapel Hill, North Carolina 27599-7025, USA, and University Hospital, Vancouver, British Columbia, Canada. xuemei@med.unc.edu</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Neurology, School of Medicine, University of North Carolina, Chapel Hill, North Carolina 27599-7025, USA, and University Hospital, Vancouver, British Columbia</wicri:regionArea><wicri:noRegion>British Columbia</wicri:noRegion></affiliation></author><author><name sortKey="Lee, Yueh Z" sort="Lee, Yueh Z" uniqKey="Lee Y" first="Yueh Z" last="Lee">Yueh Z. Lee</name></author><author><name sortKey="Mckeown, Martin" sort="Mckeown, Martin" uniqKey="Mckeown M" first="Martin" last="Mckeown">Martin Mckeown</name></author><author><name sortKey="Gerig, Guido" sort="Gerig, Guido" uniqKey="Gerig G" first="Guido" last="Gerig">Guido Gerig</name></author><author><name sortKey="Gu, Hongbin" sort="Gu, Hongbin" uniqKey="Gu H" first="Hongbin" last="Gu">Hongbin Gu</name></author><author><name sortKey="Lin, Weili" sort="Lin, Weili" uniqKey="Lin W" first="Weili" last="Lin">Weili Lin</name></author><author><name sortKey="Lewis, Mechelle M" sort="Lewis, Mechelle M" uniqKey="Lewis M" first="Mechelle M" last="Lewis">Mechelle M. Lewis</name></author><author><name sortKey="Ford, Sutapa" sort="Ford, Sutapa" uniqKey="Ford S" first="Sutapa" last="Ford">Sutapa Ford</name></author><author><name sortKey="Troster, Alexander I" sort="Troster, Alexander I" uniqKey="Troster A" first="Alexander I" last="Tröster">Alexander I. Tröster</name></author><author><name sortKey="Weinberger, Daniel R" sort="Weinberger, Daniel R" uniqKey="Weinberger D" first="Daniel R" last="Weinberger">Daniel R. Weinberger</name></author><author><name sortKey="Styner, Martin" sort="Styner, Martin" uniqKey="Styner M" first="Martin" last="Styner">Martin Styner</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="ISSN">0885-3185</idno><imprint><date when="2007" type="published">2007</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Cerebral Ventricles (pathology)</term><term>Diseases in Twins</term><term>Female</term><term>Humans</term><term>Magnetic Resonance Imaging</term><term>Male</term><term>Middle Aged</term><term>Parkinson Disease (pathology)</term><term>Twin Studies as Topic</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Cerebral Ventricles</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Diseases in Twins</term><term>Female</term><term>Humans</term><term>Magnetic Resonance Imaging</term><term>Male</term><term>Middle Aged</term><term>Twin Studies as Topic</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Parkinson's disease (PD) typically manifests with asymmetric motor symptom onset. Ventricular enlargement, a nonspecific measure of brain atrophy, has been associated with cognitive decline in PD, but not with motor symptom asymmetry. Asymmetrical ventricular enlargement on magnetic resonance images was explored in a monozygotic twin pair discordant for PD and in nine healthy monozygotic twin pairs. The left-right lateral ventricular volumetric difference of the PD-twin was greater than that of his twin and all other healthy twins, with the larger ventricle observed contralateral to the more symptomatic side. Moreover, the lateral ventricle asymmetry difference between twin pairs was significantly higher for the discordant PD-twin pair than for the healthy twin pairs. This is the first report to suggest the presence of asymmetrical ventricular enlargement in PD, findings that may be worthy of further study.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Ncbi/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001D47 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd -nk 001D47 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= Ncbi
|étape= Curation
|type= RBID
|clé= pubmed:17588238
|texte= Asymmetrical ventricular enlargement in Parkinson's disease.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/RBID.i -Sk "pubmed:17588238" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd \
| NlmPubMed2Wicri -a MovDisordV3
| This area was generated with Dilib version V0.6.23. |  |