Movement Disorders (revue)

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Smoking-responsive juvenile-onset Parkinsonism.

Identifieur interne : 001920 ( Ncbi/Curation ); précédent : 001919; suivant : 001921

Smoking-responsive juvenile-onset Parkinsonism.

Auteurs : Hasmet Ayhan Hanagasi [Turquie] ; Andrew Lees ; Janel O. Johnson ; Andrew Singleton ; Murat Emre

Source :

RBID : pubmed:17080433

English descriptors

Abstract

We describe a patient with juvenile levodopa-responsive Parkinsonism who reported a dramatic response to cigarette smoking with transient but marked improvement of motor symptoms associated with oculogyric crises and psychotic behavior. His beta-CIT single-photon emission computed tomography scan showed a complete absence of presynaptic dopaminergic nerve terminals.

DOI: 10.1002/mds.21177
PubMed: 17080433

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pubmed:17080433

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<title xml:lang="en">Smoking-responsive juvenile-onset Parkinsonism.</title>
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<name sortKey="Hanagasi, Hasmet Ayhan" sort="Hanagasi, Hasmet Ayhan" uniqKey="Hanagasi H" first="Hasmet Ayhan" last="Hanagasi">Hasmet Ayhan Hanagasi</name>
<affiliation wicri:level="1">
<nlm:affiliation>Department of Neurology, Behavioral Neurology and Movement Disorders Unit, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey. hasmet@yahoo.com</nlm:affiliation>
<country xml:lang="fr">Turquie</country>
<wicri:regionArea>Department of Neurology, Behavioral Neurology and Movement Disorders Unit, Istanbul Faculty of Medicine, Istanbul University, Istanbul</wicri:regionArea>
<wicri:noRegion>Istanbul</wicri:noRegion>
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<name sortKey="Lees, Andrew" sort="Lees, Andrew" uniqKey="Lees A" first="Andrew" last="Lees">Andrew Lees</name>
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<name sortKey="Johnson, Janel O" sort="Johnson, Janel O" uniqKey="Johnson J" first="Janel O" last="Johnson">Janel O. Johnson</name>
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<name sortKey="Singleton, Andrew" sort="Singleton, Andrew" uniqKey="Singleton A" first="Andrew" last="Singleton">Andrew Singleton</name>
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<name sortKey="Emre, Murat" sort="Emre, Murat" uniqKey="Emre M" first="Murat" last="Emre">Murat Emre</name>
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<name sortKey="Lees, Andrew" sort="Lees, Andrew" uniqKey="Lees A" first="Andrew" last="Lees">Andrew Lees</name>
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<name sortKey="Johnson, Janel O" sort="Johnson, Janel O" uniqKey="Johnson J" first="Janel O" last="Johnson">Janel O. Johnson</name>
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<name sortKey="Singleton, Andrew" sort="Singleton, Andrew" uniqKey="Singleton A" first="Andrew" last="Singleton">Andrew Singleton</name>
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<name sortKey="Emre, Murat" sort="Emre, Murat" uniqKey="Emre M" first="Murat" last="Emre">Murat Emre</name>
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<title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
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<term>Adult</term>
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<term>Male</term>
<term>Nicotine (therapeutic use)</term>
<term>Nicotinic Agonists (therapeutic use)</term>
<term>Parkinsonian Disorders (drug therapy)</term>
<term>Parkinsonian Disorders (radionuclide imaging)</term>
<term>Smoking</term>
<term>Tomography, Emission-Computed, Single-Photon</term>
<term>Tropanes (pharmacokinetics)</term>
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<term>Tropanes</term>
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<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en">
<term>Nicotine</term>
<term>Nicotinic Agonists</term>
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<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en">
<term>Parkinsonian Disorders</term>
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<keywords scheme="MESH" qualifier="radionuclide imaging" xml:lang="en">
<term>Parkinsonian Disorders</term>
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<keywords scheme="MESH" xml:lang="en">
<term>Adult</term>
<term>Humans</term>
<term>Male</term>
<term>Smoking</term>
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<div type="abstract" xml:lang="en">We describe a patient with juvenile levodopa-responsive Parkinsonism who reported a dramatic response to cigarette smoking with transient but marked improvement of motor symptoms associated with oculogyric crises and psychotic behavior. His beta-CIT single-photon emission computed tomography scan showed a complete absence of presynaptic dopaminergic nerve terminals.</div>
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