Smoking-responsive juvenile-onset Parkinsonism.
Identifieur interne : 001920 ( Ncbi/Curation ); précédent : 001919; suivant : 001921Smoking-responsive juvenile-onset Parkinsonism.
Auteurs : Hasmet Ayhan Hanagasi [Turquie] ; Andrew Lees ; Janel O. Johnson ; Andrew Singleton ; Murat EmreSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2007.
English descriptors
- KwdEn :
- MESH :
- chemical , pharmacokinetics : Tropanes.
- chemical , therapeutic use : Nicotine, Nicotinic Agonists.
- drug therapy : Parkinsonian Disorders.
- radionuclide imaging : Parkinsonian Disorders.
- Adult, Humans, Male, Smoking, Tomography, Emission-Computed, Single-Photon.
Abstract
We describe a patient with juvenile levodopa-responsive Parkinsonism who reported a dramatic response to cigarette smoking with transient but marked improvement of motor symptoms associated with oculogyric crises and psychotic behavior. His beta-CIT single-photon emission computed tomography scan showed a complete absence of presynaptic dopaminergic nerve terminals.
DOI: 10.1002/mds.21177
PubMed: 17080433
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pubmed:17080433Le document en format XML
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<author><name sortKey="Hanagasi, Hasmet Ayhan" sort="Hanagasi, Hasmet Ayhan" uniqKey="Hanagasi H" first="Hasmet Ayhan" last="Hanagasi">Hasmet Ayhan Hanagasi</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, Behavioral Neurology and Movement Disorders Unit, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey. hasmet@yahoo.com</nlm:affiliation>
<country xml:lang="fr">Turquie</country>
<wicri:regionArea>Department of Neurology, Behavioral Neurology and Movement Disorders Unit, Istanbul Faculty of Medicine, Istanbul University, Istanbul</wicri:regionArea>
<wicri:noRegion>Istanbul</wicri:noRegion>
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<author><name sortKey="Lees, Andrew" sort="Lees, Andrew" uniqKey="Lees A" first="Andrew" last="Lees">Andrew Lees</name>
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<author><name sortKey="Johnson, Janel O" sort="Johnson, Janel O" uniqKey="Johnson J" first="Janel O" last="Johnson">Janel O. Johnson</name>
</author>
<author><name sortKey="Singleton, Andrew" sort="Singleton, Andrew" uniqKey="Singleton A" first="Andrew" last="Singleton">Andrew Singleton</name>
</author>
<author><name sortKey="Emre, Murat" sort="Emre, Murat" uniqKey="Emre M" first="Murat" last="Emre">Murat Emre</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Smoking-responsive juvenile-onset Parkinsonism.</title>
<author><name sortKey="Hanagasi, Hasmet Ayhan" sort="Hanagasi, Hasmet Ayhan" uniqKey="Hanagasi H" first="Hasmet Ayhan" last="Hanagasi">Hasmet Ayhan Hanagasi</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, Behavioral Neurology and Movement Disorders Unit, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey. hasmet@yahoo.com</nlm:affiliation>
<country xml:lang="fr">Turquie</country>
<wicri:regionArea>Department of Neurology, Behavioral Neurology and Movement Disorders Unit, Istanbul Faculty of Medicine, Istanbul University, Istanbul</wicri:regionArea>
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<author><name sortKey="Lees, Andrew" sort="Lees, Andrew" uniqKey="Lees A" first="Andrew" last="Lees">Andrew Lees</name>
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<author><name sortKey="Johnson, Janel O" sort="Johnson, Janel O" uniqKey="Johnson J" first="Janel O" last="Johnson">Janel O. Johnson</name>
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<author><name sortKey="Singleton, Andrew" sort="Singleton, Andrew" uniqKey="Singleton A" first="Andrew" last="Singleton">Andrew Singleton</name>
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<author><name sortKey="Emre, Murat" sort="Emre, Murat" uniqKey="Emre M" first="Murat" last="Emre">Murat Emre</name>
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<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
<idno type="ISSN">0885-3185</idno>
<imprint><date when="2007" type="published">2007</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Humans</term>
<term>Male</term>
<term>Nicotine (therapeutic use)</term>
<term>Nicotinic Agonists (therapeutic use)</term>
<term>Parkinsonian Disorders (drug therapy)</term>
<term>Parkinsonian Disorders (radionuclide imaging)</term>
<term>Smoking</term>
<term>Tomography, Emission-Computed, Single-Photon</term>
<term>Tropanes (pharmacokinetics)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="pharmacokinetics" xml:lang="en"><term>Tropanes</term>
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<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Nicotine</term>
<term>Nicotinic Agonists</term>
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<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Parkinsonian Disorders</term>
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<keywords scheme="MESH" qualifier="radionuclide imaging" xml:lang="en"><term>Parkinsonian Disorders</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Humans</term>
<term>Male</term>
<term>Smoking</term>
<term>Tomography, Emission-Computed, Single-Photon</term>
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<front><div type="abstract" xml:lang="en">We describe a patient with juvenile levodopa-responsive Parkinsonism who reported a dramatic response to cigarette smoking with transient but marked improvement of motor symptoms associated with oculogyric crises and psychotic behavior. His beta-CIT single-photon emission computed tomography scan showed a complete absence of presynaptic dopaminergic nerve terminals.</div>
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