Holmes tremor: Application of modern neuroimaging techniques.
Identifieur interne : 001867 ( Ncbi/Curation ); précédent : 001866; suivant : 001868Holmes tremor: Application of modern neuroimaging techniques.
Auteurs : Dominic C. Paviour [Royaume-Uni] ; H Rolf J Ger ; Leonora Wilkinson ; Marjan Jahanshahi ; Andrew J. LeesSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2006.
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Abstract
Holmes tremor has a characteristic rest, intention, and postural component. The syndrome arises as a consequence of a lesion in the upper brainstem and cerebral peduncles, which, it is postulated, interrupts the cerebello-rubrothalamic pathway. Ataxia, ophthalmoplegia, and bradykinesia are associated features. We present a case of Holmes tremor secondary to a midbrain cavernoma. Modern neuroimaging techniques in this case confirm that a combination of damage to the cerebello-rubrothalamic pathway and the nigrostriatal pathway is required for the full Holmes tremor syndrome to occur.
DOI: 10.1002/mds.20981
PubMed: 17013902
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