MovDisordV3, Ncbi, Curation, bibRecord, 001684

Minor depression and brain perfusion images in Parkinson's disease.

Identifieur interne : 001684 ( Ncbi/Curation ); précédent : 001683; suivant : 001685

Minor depression and brain perfusion images in Parkinson's disease.

Auteurs : Hideaki Matsui [Japon] ; Kazuto Nishinaka ; Masaya Oda ; Kenichi Komatsu ; Tamotsu Kubori ; Fukashi Udaka

Source :

Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2006.

RBID : pubmed:16685687

English descriptors

KwdEn :
- Aged, Brain (pathology), Brain Mapping, Functional Laterality, Humans, Magnetic Resonance Imaging (methods), Middle Aged, Parkinson Disease (pathology), Parkinson Disease (physiopathology), Reproducibility of Results, Sensitivity and Specificity.
MESH :
- methods : Magnetic Resonance Imaging.
- pathology : Brain, Parkinson Disease.
- physiopathology : Parkinson Disease.
- Aged, Brain Mapping, Functional Laterality, Humans, Middle Aged, Reproducibility of Results, Sensitivity and Specificity.

Abstract

Depression is common in individuals with Parkinson's disease. However, the pathophysiology of depression in Parkinson's disease remains obscure. Here we compared brain perfusion images of Parkinson's disease patients with and without depression to investigate correlations between depression and brain perfusion images in Parkinson's disease. We divided 40 consecutive patients with Parkinson's disease into two groups: patients with minor depression (n = 22) and patients without depression (n = 18). We then compared brain perfusion images between the two groups. As a result, hypoperfusion of the left superior and inferior frontal gyrus was demonstrated in depressed patients. These results were partially in agreement with previous studies on de novo and parkinsonian major depression. We could not conclude on whether pathophysiological mechanisms differed between de novo depression and depression with Parkinson's disease, and between major and minor depressions.

DOI: 10.1002/mds.20923
PubMed: 16685687

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Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Minor depression and brain perfusion images in Parkinson's disease.</title>
<author><name sortKey="Matsui, Hideaki" sort="Matsui, Hideaki" uniqKey="Matsui H" first="Hideaki" last="Matsui">Hideaki Matsui</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, Sumitomo Hospital, Osaka, Japan. matsui-hideaki@sumitomo-hp.or.jp</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Neurology, Sumitomo Hospital, Osaka</wicri:regionArea>
<wicri:noRegion>Osaka</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Nishinaka, Kazuto" sort="Nishinaka, Kazuto" uniqKey="Nishinaka K" first="Kazuto" last="Nishinaka">Kazuto Nishinaka</name>
</author>
<author><name sortKey="Oda, Masaya" sort="Oda, Masaya" uniqKey="Oda M" first="Masaya" last="Oda">Masaya Oda</name>
</author>
<author><name sortKey="Komatsu, Kenichi" sort="Komatsu, Kenichi" uniqKey="Komatsu K" first="Kenichi" last="Komatsu">Kenichi Komatsu</name>
</author>
<author><name sortKey="Kubori, Tamotsu" sort="Kubori, Tamotsu" uniqKey="Kubori T" first="Tamotsu" last="Kubori">Tamotsu Kubori</name>
</author>
<author><name sortKey="Udaka, Fukashi" sort="Udaka, Fukashi" uniqKey="Udaka F" first="Fukashi" last="Udaka">Fukashi Udaka</name>
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<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2006">2006</date>
<idno type="doi">10.1002/mds.20923</idno>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Minor depression and brain perfusion images in Parkinson's disease.</title>
<author><name sortKey="Matsui, Hideaki" sort="Matsui, Hideaki" uniqKey="Matsui H" first="Hideaki" last="Matsui">Hideaki Matsui</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, Sumitomo Hospital, Osaka, Japan. matsui-hideaki@sumitomo-hp.or.jp</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Neurology, Sumitomo Hospital, Osaka</wicri:regionArea>
<wicri:noRegion>Osaka</wicri:noRegion>
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<author><name sortKey="Nishinaka, Kazuto" sort="Nishinaka, Kazuto" uniqKey="Nishinaka K" first="Kazuto" last="Nishinaka">Kazuto Nishinaka</name>
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<author><name sortKey="Oda, Masaya" sort="Oda, Masaya" uniqKey="Oda M" first="Masaya" last="Oda">Masaya Oda</name>
</author>
<author><name sortKey="Komatsu, Kenichi" sort="Komatsu, Kenichi" uniqKey="Komatsu K" first="Kenichi" last="Komatsu">Kenichi Komatsu</name>
</author>
<author><name sortKey="Kubori, Tamotsu" sort="Kubori, Tamotsu" uniqKey="Kubori T" first="Tamotsu" last="Kubori">Tamotsu Kubori</name>
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<author><name sortKey="Udaka, Fukashi" sort="Udaka, Fukashi" uniqKey="Udaka F" first="Fukashi" last="Udaka">Fukashi Udaka</name>
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<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
<idno type="ISSN">0885-3185</idno>
<imprint><date when="2006" type="published">2006</date>
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<term>Brain Mapping</term>
<term>Functional Laterality</term>
<term>Humans</term>
<term>Magnetic Resonance Imaging (methods)</term>
<term>Middle Aged</term>
<term>Parkinson Disease (pathology)</term>
<term>Parkinson Disease (physiopathology)</term>
<term>Reproducibility of Results</term>
<term>Sensitivity and Specificity</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Magnetic Resonance Imaging</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Brain</term>
<term>Parkinson Disease</term>
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<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Brain Mapping</term>
<term>Functional Laterality</term>
<term>Humans</term>
<term>Middle Aged</term>
<term>Reproducibility of Results</term>
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<front><div type="abstract" xml:lang="en">Depression is common in individuals with Parkinson's disease. However, the pathophysiology of depression in Parkinson's disease remains obscure. Here we compared brain perfusion images of Parkinson's disease patients with and without depression to investigate correlations between depression and brain perfusion images in Parkinson's disease. We divided 40 consecutive patients with Parkinson's disease into two groups: patients with minor depression (n = 22) and patients without depression (n = 18). We then compared brain perfusion images between the two groups. As a result, hypoperfusion of the left superior and inferior frontal gyrus was demonstrated in depressed patients. These results were partially in agreement with previous studies on de novo and parkinsonian major depression. We could not conclude on whether pathophysiological mechanisms differed between de novo depression and depression with Parkinson's disease, and between major and minor depressions.</div>
</front>
</TEI>
</record>

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	Movement Disorders (revue)
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Movement Disorders (revue)

Minor depression and brain perfusion images in Parkinson's disease.

Minor depression and brain perfusion images in Parkinson's disease.

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki