Development of Parkinson's disease in patients with blepharospasm.
Identifieur interne : 000F35 ( Ncbi/Curation ); précédent : 000F34; suivant : 000F36Development of Parkinson's disease in patients with blepharospasm.
Auteurs : Federico Micheli [Argentine] ; María Clara Scorticati ; Silvia Folgar ; Emilia GattoSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2004.
English descriptors
- KwdEn :
- Aged, Aged, 80 and over, Botulinum Toxins, Type A (therapeutic use), Brain (pathology), Brain (physiopathology), Brain (radiography), Disease Progression, Female, Humans, Magnetic Resonance Imaging, Male, Meige Syndrome (diagnosis), Meige Syndrome (drug therapy), Meige Syndrome (epidemiology), Neuromuscular Agents (therapeutic use), Parkinson Disease (diagnosis), Parkinson Disease (epidemiology), Parkinson Disease (physiopathology), Severity of Illness Index, Tomography, X-Ray Computed.
- MESH :
- chemical , therapeutic use : Botulinum Toxins, Type A, Neuromuscular Agents.
- diagnosis : Meige Syndrome, Parkinson Disease.
- drug therapy : Meige Syndrome.
- epidemiology : Meige Syndrome, Parkinson Disease.
- pathology : Brain.
- physiopathology : Brain, Parkinson Disease.
- radiography : Brain.
- Aged, Aged, 80 and over, Disease Progression, Female, Humans, Magnetic Resonance Imaging, Male, Severity of Illness Index, Tomography, X-Ray Computed.
Abstract
The liability to develop parkinsonian symptoms was evaluated in 105 outpatients with idiopathic blepharospasm (IBS; 54 cases) or IBS associated to oromandibular dystonia (Meige's syndrome; 51 cases) mean age 70.3 +/- 9.6 years, and compared with an age- and sex-matched population. Eleven patients developed Parkinson's disease in the blepharospasm group, whereas only 2 of 105 patients were affected in the control group. Our results suggest that patients with IBS either isolated or associated with oromandibular dystonia are more prone to develop parkinsonian symptoms.
DOI: 10.1002/mds.20084
PubMed: 15372598
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pubmed:15372598Le document en format XML
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<author><name sortKey="Micheli, Federico" sort="Micheli, Federico" uniqKey="Micheli F" first="Federico" last="Micheli">Federico Micheli</name>
<affiliation wicri:level="1"><nlm:affiliation>Programa de Parkinson y Movimientos Anormales, Instituto de Neurociencias, Hospital de Clínicas José de San Martín, Buenos Aires, Argentina. fmicheli@fibertel.com.ar</nlm:affiliation>
<country xml:lang="fr">Argentine</country>
<wicri:regionArea>Programa de Parkinson y Movimientos Anormales, Instituto de Neurociencias, Hospital de Clínicas José de San Martín, Buenos Aires</wicri:regionArea>
<wicri:noRegion>Buenos Aires</wicri:noRegion>
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<author><name sortKey="Scorticati, Maria Clara" sort="Scorticati, Maria Clara" uniqKey="Scorticati M" first="María Clara" last="Scorticati">María Clara Scorticati</name>
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<author><name sortKey="Folgar, Silvia" sort="Folgar, Silvia" uniqKey="Folgar S" first="Silvia" last="Folgar">Silvia Folgar</name>
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<author><name sortKey="Gatto, Emilia" sort="Gatto, Emilia" uniqKey="Gatto E" first="Emilia" last="Gatto">Emilia Gatto</name>
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<author><name sortKey="Scorticati, Maria Clara" sort="Scorticati, Maria Clara" uniqKey="Scorticati M" first="María Clara" last="Scorticati">María Clara Scorticati</name>
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<author><name sortKey="Folgar, Silvia" sort="Folgar, Silvia" uniqKey="Folgar S" first="Silvia" last="Folgar">Silvia Folgar</name>
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<author><name sortKey="Gatto, Emilia" sort="Gatto, Emilia" uniqKey="Gatto E" first="Emilia" last="Gatto">Emilia Gatto</name>
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<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
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<term>Brain (physiopathology)</term>
<term>Brain (radiography)</term>
<term>Disease Progression</term>
<term>Female</term>
<term>Humans</term>
<term>Magnetic Resonance Imaging</term>
<term>Male</term>
<term>Meige Syndrome (diagnosis)</term>
<term>Meige Syndrome (drug therapy)</term>
<term>Meige Syndrome (epidemiology)</term>
<term>Neuromuscular Agents (therapeutic use)</term>
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<term>Severity of Illness Index</term>
<term>Tomography, X-Ray Computed</term>
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<term>Neuromuscular Agents</term>
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<term>Parkinson Disease</term>
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<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Meige Syndrome</term>
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<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Meige Syndrome</term>
<term>Parkinson Disease</term>
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<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Brain</term>
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<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Brain</term>
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<term>Disease Progression</term>
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<term>Magnetic Resonance Imaging</term>
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<front><div type="abstract" xml:lang="en">The liability to develop parkinsonian symptoms was evaluated in 105 outpatients with idiopathic blepharospasm (IBS; 54 cases) or IBS associated to oromandibular dystonia (Meige's syndrome; 51 cases) mean age 70.3 +/- 9.6 years, and compared with an age- and sex-matched population. Eleven patients developed Parkinson's disease in the blepharospasm group, whereas only 2 of 105 patients were affected in the control group. Our results suggest that patients with IBS either isolated or associated with oromandibular dystonia are more prone to develop parkinsonian symptoms.</div>
</front>
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