Microelectrode recordings in the pallidum.
Identifieur interne : 000772 ( Ncbi/Curation ); précédent : 000771; suivant : 000773Microelectrode recordings in the pallidum.
Auteurs : Andres M. Lozano [Canada] ; William D. HutchisonSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2002.
English descriptors
- KwdEn :
- MESH :
- instrumentation : Monitoring, Intraoperative.
- methods : Brain Mapping, Monitoring, Intraoperative.
- physiology : Neurons.
- physiopathology : Globus Pallidus.
- surgery : Dystonia, Globus Pallidus, Parkinson Disease.
- Humans, Microelectrodes, Stereotaxic Techniques.
Abstract
The internal segment of the globus pallidus (GPi) is being targeted in neurosurgical procedures to treat Parkinson's disease and dystonia. Precise targeting of the pallidal complex is important in determining the efficacy of the surgical intervention and for the avoidance of adverse effects. Intraoperative microelectrode recording can be used to characterize the patterns of activity and receptive field properties of single pallidal neurons and to identify important bordering structures, including the optic tract and internal capsule. Because the clinical features of movement disorders can be differentially affected as a function of location within the pallidal complex, further refinements in intraoperative targeting may become important.
PubMed: 11948770
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pubmed:11948770Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Microelectrode recordings in the pallidum.</title>
<author><name sortKey="Lozano, Andres M" sort="Lozano, Andres M" uniqKey="Lozano A" first="Andres M" last="Lozano">Andres M. Lozano</name>
<affiliation wicri:level="4"><nlm:affiliation>Division of Neurosurgery, University of Toronto, The Toronto Hospital, Western Division, Toronto, Ontario, Canada. lozano@uhnres.utoronto.ca</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Division of Neurosurgery, University of Toronto, The Toronto Hospital, Western Division, Toronto, Ontario</wicri:regionArea>
<orgName type="university">Université de Toronto</orgName>
<placeName><settlement type="city">Toronto</settlement>
<region type="state">Ontario</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hutchison, William D" sort="Hutchison, William D" uniqKey="Hutchison W" first="William D" last="Hutchison">William D. Hutchison</name>
</author>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Microelectrode recordings in the pallidum.</title>
<author><name sortKey="Lozano, Andres M" sort="Lozano, Andres M" uniqKey="Lozano A" first="Andres M" last="Lozano">Andres M. Lozano</name>
<affiliation wicri:level="4"><nlm:affiliation>Division of Neurosurgery, University of Toronto, The Toronto Hospital, Western Division, Toronto, Ontario, Canada. lozano@uhnres.utoronto.ca</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Division of Neurosurgery, University of Toronto, The Toronto Hospital, Western Division, Toronto, Ontario</wicri:regionArea>
<orgName type="university">Université de Toronto</orgName>
<placeName><settlement type="city">Toronto</settlement>
<region type="state">Ontario</region>
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<author><name sortKey="Hutchison, William D" sort="Hutchison, William D" uniqKey="Hutchison W" first="William D" last="Hutchison">William D. Hutchison</name>
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<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
<idno type="ISSN">0885-3185</idno>
<imprint><date when="2002" type="published">2002</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Brain Mapping (methods)</term>
<term>Dystonia (surgery)</term>
<term>Globus Pallidus (physiopathology)</term>
<term>Globus Pallidus (surgery)</term>
<term>Humans</term>
<term>Microelectrodes</term>
<term>Monitoring, Intraoperative (instrumentation)</term>
<term>Monitoring, Intraoperative (methods)</term>
<term>Neurons (physiology)</term>
<term>Parkinson Disease (surgery)</term>
<term>Stereotaxic Techniques</term>
</keywords>
<keywords scheme="MESH" qualifier="instrumentation" xml:lang="en"><term>Monitoring, Intraoperative</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Brain Mapping</term>
<term>Monitoring, Intraoperative</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Neurons</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Globus Pallidus</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Dystonia</term>
<term>Globus Pallidus</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Humans</term>
<term>Microelectrodes</term>
<term>Stereotaxic Techniques</term>
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<front><div type="abstract" xml:lang="en">The internal segment of the globus pallidus (GPi) is being targeted in neurosurgical procedures to treat Parkinson's disease and dystonia. Precise targeting of the pallidal complex is important in determining the efficacy of the surgical intervention and for the avoidance of adverse effects. Intraoperative microelectrode recording can be used to characterize the patterns of activity and receptive field properties of single pallidal neurons and to identify important bordering structures, including the optic tract and internal capsule. Because the clinical features of movement disorders can be differentially affected as a function of location within the pallidal complex, further refinements in intraoperative targeting may become important.</div>
</front>
</TEI>
</record>
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