Movement Disorders (revue)

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Focal pathological startle following pontine infarction.

Identifieur interne : 000683 ( Ncbi/Curation ); précédent : 000682; suivant : 000684

Focal pathological startle following pontine infarction.

Auteurs : Shaun R D. Watson [Australie] ; James G. Colebatch

Source :

RBID : pubmed:11835470

English descriptors

Abstract

A 36-year-old male developed an acute right-sided weakness due to left-sided pontine infarction. Two months later, he first noticed sudden right elbow flexion in response to a loud unexpected noise. Detailed electrophysiological assessment was performed. A large, short-latency (median 39 msec), synchronous electromyographic discharge occurred in the right biceps brachii electrodes following a 50-msec, 120-dB 1-kHz tone burst, with habituation only with very short (30-second) interstimulus intervals. Less synchronous activity at longer latencies was present both in a number of right-sided arm muscles at rest and on the clinically unaffected side during a tonic voluntary contraction. We discuss possible underlying mechanisms and our reasons for considering this a focally enhanced startle response. Our report broadens the range of expression of acquired startle disorders.

PubMed: 11835470

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pubmed:11835470

Le document en format XML

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<nlm:affiliation>Institute of Neurological Sciences, Department of Neurology and Clinical School, Prince of Wales Hospital, Randwick, Sydney 2031, Australia.</nlm:affiliation>
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<term>Evoked Potentials, Auditory, Brain Stem</term>
<term>Evoked Potentials, Somatosensory</term>
<term>Humans</term>
<term>Magnetic Resonance Imaging</term>
<term>Male</term>
<term>Muscle Weakness (diagnosis)</term>
<term>Muscle Weakness (etiology)</term>
<term>Pons (blood supply)</term>
<term>Pons (pathology)</term>
<term>Reflex, Startle (physiology)</term>
<term>Videotape Recording</term>
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<term>Muscle Weakness</term>
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<term>Reflex, Startle</term>
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<div type="abstract" xml:lang="en">A 36-year-old male developed an acute right-sided weakness due to left-sided pontine infarction. Two months later, he first noticed sudden right elbow flexion in response to a loud unexpected noise. Detailed electrophysiological assessment was performed. A large, short-latency (median 39 msec), synchronous electromyographic discharge occurred in the right biceps brachii electrodes following a 50-msec, 120-dB 1-kHz tone burst, with habituation only with very short (30-second) interstimulus intervals. Less synchronous activity at longer latencies was present both in a number of right-sided arm muscles at rest and on the clinically unaffected side during a tonic voluntary contraction. We discuss possible underlying mechanisms and our reasons for considering this a focally enhanced startle response. Our report broadens the range of expression of acquired startle disorders.</div>
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