Longitudinal evolution of prefrontal leucotomy in Tourette's syndrome.
Identifieur interne : 004734 ( Ncbi/Checkpoint ); précédent : 004733; suivant : 004735Longitudinal evolution of prefrontal leucotomy in Tourette's syndrome.
Auteurs : J. Kulisevsky [Espagne] ; M L Berthier ; A. AvilaSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 1995.
English descriptors
- KwdEn :
- MESH :
- physiology : Dominance, Cerebral.
- physiopathology : Prefrontal Cortex, Tourette Syndrome.
- surgery : Prefrontal Cortex, Tourette Syndrome.
- Aged, Brain Mapping, Humans, Longitudinal Studies, Male, Psychosurgery, Treatment Outcome.
Abstract
We report the case of a 69-year-old man with severe Tourette's syndrome (TS) who underwent a bilateral prefrontal leucotomy at the age of 29 years to alleviate coprolalia, copropraxia, and obsessive-compulsive disorder. No improvement was observed during the 5 years after the leucotomy. Tics and associated behavioral abnormalities disappeared thereafter, to recur at age 67. Long-term follow-up of single cases can help to estimate the role of neurosurgery in the treatment of TS.
DOI: 10.1002/mds.870100320
PubMed: 7651455
Affiliations:
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pubmed:7651455Le document en format XML
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<author><name sortKey="Kulisevsky, J" sort="Kulisevsky, J" uniqKey="Kulisevsky J" first="J" last="Kulisevsky">J. Kulisevsky</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, Sant Pau Hospital, Autonomous University of Barcelona, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
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<wicri:noRegion>Autonomous University of Barcelona</wicri:noRegion>
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<author><name sortKey="Berthier, M L" sort="Berthier, M L" uniqKey="Berthier M" first="M L" last="Berthier">M L Berthier</name>
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<author><name sortKey="Avila, A" sort="Avila, A" uniqKey="Avila A" first="A" last="Avila">A. Avila</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Longitudinal evolution of prefrontal leucotomy in Tourette's syndrome.</title>
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<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
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<term>Longitudinal Studies</term>
<term>Male</term>
<term>Prefrontal Cortex (physiopathology)</term>
<term>Prefrontal Cortex (surgery)</term>
<term>Psychosurgery</term>
<term>Tourette Syndrome (physiopathology)</term>
<term>Tourette Syndrome (surgery)</term>
<term>Treatment Outcome</term>
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<front><div type="abstract" xml:lang="en">We report the case of a 69-year-old man with severe Tourette's syndrome (TS) who underwent a bilateral prefrontal leucotomy at the age of 29 years to alleviate coprolalia, copropraxia, and obsessive-compulsive disorder. No improvement was observed during the 5 years after the leucotomy. Tics and associated behavioral abnormalities disappeared thereafter, to recur at age 67. Long-term follow-up of single cases can help to estimate the role of neurosurgery in the treatment of TS.</div>
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