Anticholinergic-induced chorea in the treatment of focal dystonia.
Identifieur interne : 004659 ( Ncbi/Checkpoint ); précédent : 004658; suivant : 004660Anticholinergic-induced chorea in the treatment of focal dystonia.
Auteurs : M. Nomoto [Royaume-Uni] ; P D Thompson ; M P Sheehy ; N P Quinn ; C D MarsdenSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 1987.
English descriptors
- KwdEn :
- MESH :
- chemical , administration & dosage : Trihexyphenidyl.
- chemical , adverse effects : Trihexyphenidyl.
- chemically induced : Chorea.
- drug therapy : Dystonia.
- Adult, Aged, Drug Administration Schedule, Female, Humans, Male, Middle Aged.
Abstract
The occurrence of chorea, induced by trihexyphenidyl (benzhexol hydrochloride) during the treatment of five adult patients who had focal or segmental dystonia, is described. The dose at which chorea appeared ranged from 15 to 60 mg/day (mean 31.7 mg/day). All but one patient had developed common adverse effects of this drug (dry mouth, blurred vision, and confusion) at lower doses (mean 21.8 mg per day). There was an inverse relationship between the age of the patient and the dose of trihexyphenidyl at which chorea developed.
DOI: 10.1002/mds.870020107
PubMed: 3504259
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 005079
- to stream PubMed, to step Curation: 005079
- to stream PubMed, to step Checkpoint: 005090
- to stream Ncbi, to step Merge: 004659
- to stream Ncbi, to step Curation: 004659
Links to Exploration step
pubmed:3504259Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Anticholinergic-induced chorea in the treatment of focal dystonia.</title><author><name sortKey="Nomoto, M" sort="Nomoto, M" uniqKey="Nomoto M" first="M" last="Nomoto">M. Nomoto</name><affiliation wicri:level="2"><nlm:affiliation>University Department of Neurology, Institute of Psychiatry, Denmark Hill, London, England.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Angleterre</region></placeName><wicri:cityArea>University Department of Neurology, Institute of Psychiatry, Denmark Hill, London</wicri:cityArea></affiliation></author><author><name sortKey="Thompson, P D" sort="Thompson, P D" uniqKey="Thompson P" first="P D" last="Thompson">P D Thompson</name></author><author><name sortKey="Sheehy, M P" sort="Sheehy, M P" uniqKey="Sheehy M" first="M P" last="Sheehy">M P Sheehy</name></author><author><name sortKey="Quinn, N P" sort="Quinn, N P" uniqKey="Quinn N" first="N P" last="Quinn">N P Quinn</name></author><author><name sortKey="Marsden, C D" sort="Marsden, C D" uniqKey="Marsden C" first="C D" last="Marsden">C D Marsden</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1987">1987</date><idno type="RBID">pubmed:3504259</idno><idno type="pmid">3504259</idno><idno type="doi">10.1002/mds.870020107</idno><idno type="wicri:Area/PubMed/Corpus">005079</idno><idno type="wicri:Area/PubMed/Curation">005079</idno><idno type="wicri:Area/PubMed/Checkpoint">005090</idno><idno type="wicri:Area/Ncbi/Merge">004659</idno><idno type="wicri:Area/Ncbi/Curation">004659</idno><idno type="wicri:Area/Ncbi/Checkpoint">004659</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Anticholinergic-induced chorea in the treatment of focal dystonia.</title><author><name sortKey="Nomoto, M" sort="Nomoto, M" uniqKey="Nomoto M" first="M" last="Nomoto">M. Nomoto</name><affiliation wicri:level="2"><nlm:affiliation>University Department of Neurology, Institute of Psychiatry, Denmark Hill, London, England.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Angleterre</region></placeName><wicri:cityArea>University Department of Neurology, Institute of Psychiatry, Denmark Hill, London</wicri:cityArea></affiliation></author><author><name sortKey="Thompson, P D" sort="Thompson, P D" uniqKey="Thompson P" first="P D" last="Thompson">P D Thompson</name></author><author><name sortKey="Sheehy, M P" sort="Sheehy, M P" uniqKey="Sheehy M" first="M P" last="Sheehy">M P Sheehy</name></author><author><name sortKey="Quinn, N P" sort="Quinn, N P" uniqKey="Quinn N" first="N P" last="Quinn">N P Quinn</name></author><author><name sortKey="Marsden, C D" sort="Marsden, C D" uniqKey="Marsden C" first="C D" last="Marsden">C D Marsden</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="ISSN">0885-3185</idno><imprint><date when="1987" type="published">1987</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Chorea (chemically induced)</term><term>Drug Administration Schedule</term><term>Dystonia (drug therapy)</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Trihexyphenidyl (administration & dosage)</term><term>Trihexyphenidyl (adverse effects)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Trihexyphenidyl</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Trihexyphenidyl</term></keywords><keywords scheme="MESH" qualifier="chemically induced" xml:lang="en"><term>Chorea</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Dystonia</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Drug Administration Schedule</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The occurrence of chorea, induced by trihexyphenidyl (benzhexol hydrochloride) during the treatment of five adult patients who had focal or segmental dystonia, is described. The dose at which chorea appeared ranged from 15 to 60 mg/day (mean 31.7 mg/day). All but one patient had developed common adverse effects of this drug (dry mouth, blurred vision, and confusion) at lower doses (mean 21.8 mg per day). There was an inverse relationship between the age of the patient and the dose of trihexyphenidyl at which chorea developed.</div></front></TEI><affiliations><list><country><li>Royaume-Uni</li></country><region><li>Angleterre</li></region></list><tree><noCountry><name sortKey="Marsden, C D" sort="Marsden, C D" uniqKey="Marsden C" first="C D" last="Marsden">C D Marsden</name><name sortKey="Quinn, N P" sort="Quinn, N P" uniqKey="Quinn N" first="N P" last="Quinn">N P Quinn</name><name sortKey="Sheehy, M P" sort="Sheehy, M P" uniqKey="Sheehy M" first="M P" last="Sheehy">M P Sheehy</name><name sortKey="Thompson, P D" sort="Thompson, P D" uniqKey="Thompson P" first="P D" last="Thompson">P D Thompson</name></noCountry><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Nomoto, M" sort="Nomoto, M" uniqKey="Nomoto M" first="M" last="Nomoto">M. Nomoto</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Ncbi/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 004659 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Checkpoint/biblio.hfd -nk 004659 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= Ncbi
|étape= Checkpoint
|type= RBID
|clé= pubmed:3504259
|texte= Anticholinergic-induced chorea in the treatment of focal dystonia.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Checkpoint/RBID.i -Sk "pubmed:3504259" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Checkpoint/biblio.hfd \
| NlmPubMed2Wicri -a MovDisordV3
| This area was generated with Dilib version V0.6.23. |  |