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Usefulness of the Montreal Cognitive Assessment (MoCA) in Huntington’s disease

Identifieur interne : 003C12 ( Ncbi/Checkpoint ); précédent : 003C11; suivant : 003C13

Usefulness of the Montreal Cognitive Assessment (MoCA) in Huntington’s disease

Auteurs : Shea Gluhm [États-Unis] ; Jody Goldstein [États-Unis] ; Daniel Brown [États-Unis] ; Charles Van Liew [États-Unis] ; Paul E. Gilbert [États-Unis] ; Jody Corey-Bloom [États-Unis]

Source :

Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2013.

RBID : PMC:4347861

English descriptors

KwdEn :
- Adult, Aged, Cognition, Cognition Disorders (complications), Cognition Disorders (diagnosis), Cognition Disorders (psychology), Executive Function, Female, Humans, Huntington Disease (complications), Huntington Disease (psychology), Male, Middle Aged, Neuropsychological Tests.
MESH :
- complications : Cognition Disorders, Huntington Disease.
- diagnosis : Cognition Disorders.
- psychology : Cognition Disorders, Huntington Disease.
- Adult, Aged, Cognition, Executive Function, Female, Humans, Male, Middle Aged, Neuropsychological Tests.

Abstract

The Montreal Cognitive Assessment (MoCA) is a brief screening instrument for dementia that is sensitive to executive dysfunction. This study examined its usefulness for assessing cognitive performance in mild, moderate, and severe Huntington’s disease (HD), as compared to the MMSE. We compared MoCA and MMSE total scores and the number of correct answers in five cognitive-specific domains in 104 manifest HD patients and 100 matched controls. For the total HD sample, and for the moderate and severe patients, significant differences between both MoCA and MMSE total scores and almost all cognitive-specific domains emerged. Even mild HD subjects showed significant differences with regard to total score and several cognitive domains on both instruments. We conclude that the MoCA, although not necessarily superior to the MMSE, is a useful instrument for assessing cognitive performance over a broad level of functioning in HD.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347861

DOI: 10.1002/mds.25578
PubMed: 23798501
PubMed Central: 4347861

Affiliations:

Links to Exploration step

PMC:4347861

Le document en format XML

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<front><div type="abstract" xml:lang="en"><p id="P2">The Montreal Cognitive Assessment (MoCA) is a brief screening instrument for dementia that is sensitive to executive dysfunction. This study examined its usefulness for assessing cognitive performance in mild, moderate, and severe Huntington’s disease (HD), as compared to the MMSE. We compared MoCA and MMSE total scores and the number of correct answers in five cognitive-specific domains in 104 manifest HD patients and 100 matched controls. For the total HD sample, and for the moderate and severe patients, significant differences between both MoCA and MMSE total scores and almost all cognitive-specific domains emerged. Even mild HD subjects showed significant differences with regard to total score and several cognitive domains on both instruments. We conclude that the MoCA, although not necessarily superior to the MMSE, is a useful instrument for assessing cognitive performance over a broad level of functioning in HD.</p>
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Movement Disorders (revue)

Usefulness of the Montreal Cognitive Assessment (MoCA) in Huntington’s disease

Usefulness of the Montreal Cognitive Assessment (MoCA) in Huntington’s disease

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English descriptors

Abstract

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	Movement Disorders (revue)
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