The current and projected economic burden of Parkinson's disease in the United States.
Identifieur interne : 003A63 ( Ncbi/Checkpoint ); précédent : 003A62; suivant : 003A64The current and projected economic burden of Parkinson's disease in the United States.
Auteurs : Stacey L. Kowal [États-Unis] ; Timothy M. Dall ; Ritashree Chakrabarti ; Michael V. Storm ; Anjali JainSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2013.
Descripteurs français
- Wicri :
- geographic : États-Unis.
English descriptors
- KwdEn :
- Adult, Age Factors, Aged, Aged, 80 and over, Cost of Illness, Disease Progression, Female, Health Care Costs (statistics & numerical data), Health Surveys, Humans, Male, Middle Aged, Parkinson Disease (economics), Parkinson Disease (epidemiology), Parkinson Disease (therapy), Prevalence, Retrospective Studies, Sex Factors, Time Factors, United States (epidemiology).
- MESH :
- geographic , epidemiology : United States.
- economics : Parkinson Disease.
- epidemiology : Parkinson Disease.
- statistics & numerical data : Health Care Costs.
- therapy : Parkinson Disease.
- Adult, Age Factors, Aged, Aged, 80 and over, Cost of Illness, Disease Progression, Female, Health Surveys, Humans, Male, Middle Aged, Prevalence, Retrospective Studies, Sex Factors, Time Factors.
Abstract
Parkinson's disease (PD), following Alzheimer's disease, is the second-most common neurodegenerative disorder in the United States. A lack of treatment options for changing the trajectory of disease progression, in combination with an increasing elderly population, portends a rising economic burden on patients and payers. This study combined information from nationally representative surveys to create a burden of PD model. The model estimates disease prevalence, excess healthcare use and medical costs, and nonmedical costs for each demographic group defined by age and sex. Estimated prevalence rates and costs were applied to the U.S. Census Bureau's 2010 to 2050 population data to estimate current and projected burden based on changing demographics. We estimate that approximately 630,000 people in the United States had diagnosed PD in 2010, with diagnosed prevalence likely to double by 2040. The national economic burden of PD exceeds $14.4 billion in 2010 (approximately $22,800 per patient). The population with PD incurred medical expenses of approximately $14 billion in 2010, $8.1 billion higher ($12,800 per capita) than expected for a similar population without PD. Indirect costs (e.g., reduced employment) are conservatively estimated at $6.3 billion (or close to $10,000 per person with PD). The burden of chronic conditions such as PD is projected to grow substantially over the next few decades as the size of the elderly population grows. Such projections give impetus to the need for innovative new treatments to prevent, delay onset, or alleviate symptoms of PD and other similar diseases.
DOI: 10.1002/mds.25292
PubMed: 23436720
Affiliations:
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Dall</name></author><author><name sortKey="Chakrabarti, Ritashree" sort="Chakrabarti, Ritashree" uniqKey="Chakrabarti R" first="Ritashree" last="Chakrabarti">Ritashree Chakrabarti</name></author><author><name sortKey="Storm, Michael V" sort="Storm, Michael V" uniqKey="Storm M" first="Michael V" last="Storm">Michael V. Storm</name></author><author><name sortKey="Jain, Anjali" sort="Jain, Anjali" uniqKey="Jain A" first="Anjali" last="Jain">Anjali Jain</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2013">2013</date><idno type="doi">10.1002/mds.25292</idno><idno type="RBID">pubmed:23436720</idno><idno type="pmid">23436720</idno><idno type="wicri:Area/PubMed/Corpus">000A18</idno><idno type="wicri:Area/PubMed/Curation">000A18</idno><idno type="wicri:Area/PubMed/Checkpoint">000768</idno><idno type="wicri:Area/Ncbi/Merge">003A63</idno><idno type="wicri:Area/Ncbi/Curation">003A63</idno><idno type="wicri:Area/Ncbi/Checkpoint">003A63</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">The current and projected economic burden of Parkinson's disease in the United States.</title><author><name sortKey="Kowal, Stacey L" sort="Kowal, Stacey L" uniqKey="Kowal S" first="Stacey L" last="Kowal">Stacey L. Kowal</name><affiliation wicri:level="2"><nlm:affiliation>IHS Global Inc., Washington, DC 20036, USA. Stacey.Kowal@ihs.com</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>IHS Global Inc., Washington, DC 20036</wicri:regionArea><placeName><region type="state">District de Columbia</region></placeName></affiliation></author><author><name sortKey="Dall, Timothy M" sort="Dall, Timothy M" uniqKey="Dall T" first="Timothy M" last="Dall">Timothy M. Dall</name></author><author><name sortKey="Chakrabarti, Ritashree" sort="Chakrabarti, Ritashree" uniqKey="Chakrabarti R" first="Ritashree" last="Chakrabarti">Ritashree Chakrabarti</name></author><author><name sortKey="Storm, Michael V" sort="Storm, Michael V" uniqKey="Storm M" first="Michael V" last="Storm">Michael V. Storm</name></author><author><name sortKey="Jain, Anjali" sort="Jain, Anjali" uniqKey="Jain A" first="Anjali" last="Jain">Anjali Jain</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="eISSN">1531-8257</idno><imprint><date when="2013" type="published">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Age Factors</term><term>Aged</term><term>Aged, 80 and over</term><term>Cost of Illness</term><term>Disease Progression</term><term>Female</term><term>Health Care Costs (statistics & numerical data)</term><term>Health Surveys</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Parkinson Disease (economics)</term><term>Parkinson Disease (epidemiology)</term><term>Parkinson Disease (therapy)</term><term>Prevalence</term><term>Retrospective Studies</term><term>Sex Factors</term><term>Time Factors</term><term>United States (epidemiology)</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>United States</term></keywords><keywords scheme="MESH" qualifier="economics" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Health Care Costs</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Age Factors</term><term>Aged</term><term>Aged, 80 and over</term><term>Cost of Illness</term><term>Disease Progression</term><term>Female</term><term>Health Surveys</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Prevalence</term><term>Retrospective Studies</term><term>Sex Factors</term><term>Time Factors</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>États-Unis</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Parkinson's disease (PD), following Alzheimer's disease, is the second-most common neurodegenerative disorder in the United States. A lack of treatment options for changing the trajectory of disease progression, in combination with an increasing elderly population, portends a rising economic burden on patients and payers. This study combined information from nationally representative surveys to create a burden of PD model. The model estimates disease prevalence, excess healthcare use and medical costs, and nonmedical costs for each demographic group defined by age and sex. Estimated prevalence rates and costs were applied to the U.S. Census Bureau's 2010 to 2050 population data to estimate current and projected burden based on changing demographics. We estimate that approximately 630,000 people in the United States had diagnosed PD in 2010, with diagnosed prevalence likely to double by 2040. The national economic burden of PD exceeds $14.4 billion in 2010 (approximately $22,800 per patient). The population with PD incurred medical expenses of approximately $14 billion in 2010, $8.1 billion higher ($12,800 per capita) than expected for a similar population without PD. Indirect costs (e.g., reduced employment) are conservatively estimated at $6.3 billion (or close to $10,000 per person with PD). The burden of chronic conditions such as PD is projected to grow substantially over the next few decades as the size of the elderly population grows. Such projections give impetus to the need for innovative new treatments to prevent, delay onset, or alleviate symptoms of PD and other similar diseases.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>District de Columbia</li></region></list><tree><noCountry><name sortKey="Chakrabarti, Ritashree" sort="Chakrabarti, Ritashree" uniqKey="Chakrabarti R" first="Ritashree" last="Chakrabarti">Ritashree Chakrabarti</name><name sortKey="Dall, Timothy M" sort="Dall, Timothy M" uniqKey="Dall T" first="Timothy M" last="Dall">Timothy M. Dall</name><name sortKey="Jain, Anjali" sort="Jain, Anjali" uniqKey="Jain A" first="Anjali" last="Jain">Anjali Jain</name><name sortKey="Storm, Michael V" sort="Storm, Michael V" uniqKey="Storm M" first="Michael V" last="Storm">Michael V. Storm</name></noCountry><country name="États-Unis"><region name="District de Columbia"><name sortKey="Kowal, Stacey L" sort="Kowal, Stacey L" uniqKey="Kowal S" first="Stacey L" last="Kowal">Stacey L. Kowal</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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