A comparison of two brief screening measures of cognitive impairment in Huntington's disease.
Identifieur interne : 002D97 ( Ncbi/Checkpoint ); précédent : 002D96; suivant : 002D98A comparison of two brief screening measures of cognitive impairment in Huntington's disease.
Auteurs : Laura Mickes [États-Unis] ; Mark Jacobson ; Guerry Peavy ; John T. Wixted ; Stephanie Lessig ; Jody L. Goldstein ; Jody Corey-BloomSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2010.
English descriptors
- KwdEn :
- MESH :
- complications : Huntington Disease.
- diagnosis : Cognition Disorders.
- etiology : Cognition Disorders.
- physiology : Executive Function.
- Adult, Area Under Curve, Female, Humans, Male, Mental Status Schedule, Middle Aged, Neuropsychological Tests, ROC Curve.
Abstract
The goal of this study was to explore whether the Montreal Cognitive Assessment (MoCA), a new screening instrument, would be more sensitive to mild to moderate cognitive impairment in Huntington's disease (HD) than an established screening measure, the Mini Mental State Exam (MMSE). Our reasoning for this query is that the MoCA includes a broader range of test items and an additional assessment of executive functioning and attention compared with the MMSE. Using the receiver operating characteristic (ROC) analysis to examine performance of HD and control groups on both tests on overall scores and scores from various subdomains (i.e., visuospatial abilities) revealed that the MoCA achieved higher sensitivity without sacrificing specificity in many domains relative to the MMSE.
DOI: 10.1002/mds.23181
PubMed: 20721924
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">A comparison of two brief screening measures of cognitive impairment in Huntington's disease.</title><author><name sortKey="Mickes, Laura" sort="Mickes, Laura" uniqKey="Mickes L" first="Laura" last="Mickes">Laura Mickes</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychology, University of California, San Diego, La Jolla, California 92093-0109, USA. lmickes@ucsd.edu</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychology, University of California, San Diego, La Jolla, California 92093-0109</wicri:regionArea><wicri:noRegion>California 92093-0109</wicri:noRegion></affiliation></author><author><name sortKey="Jacobson, Mark" sort="Jacobson, Mark" uniqKey="Jacobson M" first="Mark" last="Jacobson">Mark Jacobson</name></author><author><name sortKey="Peavy, Guerry" sort="Peavy, Guerry" uniqKey="Peavy G" first="Guerry" last="Peavy">Guerry Peavy</name></author><author><name sortKey="Wixted, John T" sort="Wixted, John T" uniqKey="Wixted J" first="John T" last="Wixted">John T. Wixted</name></author><author><name sortKey="Lessig, Stephanie" sort="Lessig, Stephanie" uniqKey="Lessig S" first="Stephanie" last="Lessig">Stephanie Lessig</name></author><author><name sortKey="Goldstein, Jody L" sort="Goldstein, Jody L" uniqKey="Goldstein J" first="Jody L" last="Goldstein">Jody L. Goldstein</name></author><author><name sortKey="Corey Bloom, Jody" sort="Corey Bloom, Jody" uniqKey="Corey Bloom J" first="Jody" last="Corey-Bloom">Jody Corey-Bloom</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2010">2010</date><idno type="doi">10.1002/mds.23181</idno><idno type="RBID">pubmed:20721924</idno><idno type="pmid">20721924</idno><idno type="wicri:Area/PubMed/Corpus">001620</idno><idno type="wicri:Area/PubMed/Curation">001620</idno><idno type="wicri:Area/PubMed/Checkpoint">001A82</idno><idno type="wicri:Area/Ncbi/Merge">002D97</idno><idno type="wicri:Area/Ncbi/Curation">002D97</idno><idno type="wicri:Area/Ncbi/Checkpoint">002D97</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">A comparison of two brief screening measures of cognitive impairment in Huntington's disease.</title><author><name sortKey="Mickes, Laura" sort="Mickes, Laura" uniqKey="Mickes L" first="Laura" last="Mickes">Laura Mickes</name><affiliation wicri:level="1"><nlm:affiliation>Department of Psychology, University of California, San Diego, La Jolla, California 92093-0109, USA. lmickes@ucsd.edu</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Psychology, University of California, San Diego, La Jolla, California 92093-0109</wicri:regionArea><wicri:noRegion>California 92093-0109</wicri:noRegion></affiliation></author><author><name sortKey="Jacobson, Mark" sort="Jacobson, Mark" uniqKey="Jacobson M" first="Mark" last="Jacobson">Mark Jacobson</name></author><author><name sortKey="Peavy, Guerry" sort="Peavy, Guerry" uniqKey="Peavy G" first="Guerry" last="Peavy">Guerry Peavy</name></author><author><name sortKey="Wixted, John T" sort="Wixted, John T" uniqKey="Wixted J" first="John T" last="Wixted">John T. Wixted</name></author><author><name sortKey="Lessig, Stephanie" sort="Lessig, Stephanie" uniqKey="Lessig S" first="Stephanie" last="Lessig">Stephanie Lessig</name></author><author><name sortKey="Goldstein, Jody L" sort="Goldstein, Jody L" uniqKey="Goldstein J" first="Jody L" last="Goldstein">Jody L. Goldstein</name></author><author><name sortKey="Corey Bloom, Jody" sort="Corey Bloom, Jody" uniqKey="Corey Bloom J" first="Jody" last="Corey-Bloom">Jody Corey-Bloom</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="eISSN">1531-8257</idno><imprint><date when="2010" type="published">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Area Under Curve</term><term>Cognition Disorders (diagnosis)</term><term>Cognition Disorders (etiology)</term><term>Executive Function (physiology)</term><term>Female</term><term>Humans</term><term>Huntington Disease (complications)</term><term>Male</term><term>Mental Status Schedule</term><term>Middle Aged</term><term>Neuropsychological Tests</term><term>ROC Curve</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Huntington Disease</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Cognition Disorders</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Cognition Disorders</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Executive Function</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Area Under Curve</term><term>Female</term><term>Humans</term><term>Male</term><term>Mental Status Schedule</term><term>Middle Aged</term><term>Neuropsychological Tests</term><term>ROC Curve</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The goal of this study was to explore whether the Montreal Cognitive Assessment (MoCA), a new screening instrument, would be more sensitive to mild to moderate cognitive impairment in Huntington's disease (HD) than an established screening measure, the Mini Mental State Exam (MMSE). Our reasoning for this query is that the MoCA includes a broader range of test items and an additional assessment of executive functioning and attention compared with the MMSE. Using the receiver operating characteristic (ROC) analysis to examine performance of HD and control groups on both tests on overall scores and scores from various subdomains (i.e., visuospatial abilities) revealed that the MoCA achieved higher sensitivity without sacrificing specificity in many domains relative to the MMSE.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country></list><tree><noCountry><name sortKey="Corey Bloom, Jody" sort="Corey Bloom, Jody" uniqKey="Corey Bloom J" first="Jody" last="Corey-Bloom">Jody Corey-Bloom</name><name sortKey="Goldstein, Jody L" sort="Goldstein, Jody L" uniqKey="Goldstein J" first="Jody L" last="Goldstein">Jody L. Goldstein</name><name sortKey="Jacobson, Mark" sort="Jacobson, Mark" uniqKey="Jacobson M" first="Mark" last="Jacobson">Mark Jacobson</name><name sortKey="Lessig, Stephanie" sort="Lessig, Stephanie" uniqKey="Lessig S" first="Stephanie" last="Lessig">Stephanie Lessig</name><name sortKey="Peavy, Guerry" sort="Peavy, Guerry" uniqKey="Peavy G" first="Guerry" last="Peavy">Guerry Peavy</name><name sortKey="Wixted, John T" sort="Wixted, John T" uniqKey="Wixted J" first="John T" last="Wixted">John T. Wixted</name></noCountry><country name="États-Unis"><noRegion><name sortKey="Mickes, Laura" sort="Mickes, Laura" uniqKey="Mickes L" first="Laura" last="Mickes">Laura Mickes</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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