Medical Decision-Making Capacity in Cognitively Impaired Parkinson's Disease Patients Without Dementia
Identifieur interne : 002296 ( Ncbi/Checkpoint ); précédent : 002295; suivant : 002297Medical Decision-Making Capacity in Cognitively Impaired Parkinson's Disease Patients Without Dementia
Auteurs : Roy C. Martin [États-Unis] ; Ozioma C. Okonkwo [États-Unis] ; Joni Hill [États-Unis] ; H. Randall Griffith [États-Unis] ; Kristen Triebel [États-Unis] ; Alfred Bartolucci [États-Unis] ; Anthony P. Nicholas [États-Unis] ; Ray L. Watts [États-Unis] ; Natividad Stover [États-Unis] ; Lindy E. Harrell [États-Unis] ; David Clark [États-Unis] ; Daniel C. Marson [États-Unis]Source :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2008.
English descriptors
- KwdEn :
- Aged, Case-Control Studies, Cognition Disorders (complications), Cognition Disorders (psychology), Decision Making (physiology), Dementia (complications), Female, Humans, Informed Consent (psychology), Informed Consent (standards), Male, Mental Competency, Middle Aged, Neuropsychological Tests, Parkinson Disease (complications), Parkinson Disease (psychology), Physician-Patient Relations, Retrospective Studies.
- MESH :
- complications : Cognition Disorders, Dementia, Parkinson Disease.
- physiology : Decision Making.
- psychology : Cognition Disorders, Informed Consent, Parkinson Disease.
- standards : Informed Consent.
- Aged, Case-Control Studies, Female, Humans, Male, Mental Competency, Middle Aged, Neuropsychological Tests, Physician-Patient Relations, Retrospective Studies.
Abstract
Little is currently known about the higher order functional skills of patients with Parkinson disease and cognitive impairment. Medical decision-making capacity (MDC) was assessed in patients with Parkinson's disease (PD) with cognitive impairment and dementia. Participants were 16 patients with PD and cognitive impairment without dementia (PD-CIND), 16 patients with PD dementia (PDD), and 22 healthy older adults. All participants were administered the Capacity to Consent to Treatment Instrument (CCTI), a standardized capacity instrument assessing MDC under five different consent standards. Parametric and non-parametric statistical analyses were utilized to examine capacity performance on the consent standards. In addition, capacity outcomes (capable, marginally capable, or incapable outcomes) on the standards were identified for the two patient groups. Relative to controls, PD-CIND patients demonstrated significant impairment on the understanding treatment consent standard, clinically the most stringent CCTI standard. Relative to controls and PD-CIND patients, patients with PDD patients were impaired on the three clinical standards of
Url:
DOI: 10.1002/mds.22170
PubMed: 18759361
PubMed Central: 2579319
Affiliations:
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Martin</name><affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation></author><author><name sortKey="Okonkwo, Ozioma C" sort="Okonkwo, Ozioma C" uniqKey="Okonkwo O" first="Ozioma C." last="Okonkwo">Ozioma C. Okonkwo</name><affiliation wicri:level="2"><nlm:aff id="A3"> Department of Psychology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Department of Psychology, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation></author><author><name sortKey="Hill, Joni" sort="Hill, Joni" uniqKey="Hill J" first="Joni" last="Hill">Joni Hill</name><affiliation wicri:level="2"><nlm:aff id="A3"> Department of Psychology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Department of Psychology, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation></author><author><name sortKey="Griffith, H Randall" sort="Griffith, H Randall" uniqKey="Griffith H" first="H. Randall" last="Griffith">H. Randall Griffith</name><affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation></author><author><name sortKey="Triebel, Kristen" sort="Triebel, Kristen" uniqKey="Triebel K" first="Kristen" last="Triebel">Kristen Triebel</name><affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation></author><author><name sortKey="Bartolucci, Alfred" sort="Bartolucci, Alfred" uniqKey="Bartolucci A" first="Alfred" last="Bartolucci">Alfred Bartolucci</name><affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A4"> Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Department of Biostatistics, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation></author><author><name sortKey="Nicholas, Anthony P" sort="Nicholas, Anthony P" uniqKey="Nicholas A" first="Anthony P." last="Nicholas">Anthony P. Nicholas</name><affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A5"> Veterans Administration Medical Center, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Veterans Administration Medical Center, Birmingham</wicri:cityArea></affiliation></author><author><name sortKey="Watts, Ray L" sort="Watts, Ray L" uniqKey="Watts R" first="Ray L." last="Watts">Ray L. Watts</name><affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation></author><author><name sortKey="Stover, Natividad" sort="Stover, Natividad" uniqKey="Stover N" first="Natividad" last="Stover">Natividad Stover</name><affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation></author><author><name sortKey="Harrell, Lindy E" sort="Harrell, Lindy E" uniqKey="Harrell L" first="Lindy E." last="Harrell">Lindy E. Harrell</name><affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A4"> Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Department of Biostatistics, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A5"> Veterans Administration Medical Center, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Veterans Administration Medical Center, Birmingham</wicri:cityArea></affiliation></author><author><name sortKey="Clark, David" sort="Clark, David" uniqKey="Clark D" first="David" last="Clark">David Clark</name><affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A4"> Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Department of Biostatistics, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A5"> Veterans Administration Medical Center, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Veterans Administration Medical Center, Birmingham</wicri:cityArea></affiliation></author><author><name sortKey="Marson, Daniel C" sort="Marson, Daniel C" uniqKey="Marson D" first="Daniel C." last="Marson">Daniel C. Marson</name><affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">18759361</idno><idno type="pmc">2579319</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579319</idno><idno type="RBID">PMC:2579319</idno><idno type="doi">10.1002/mds.22170</idno><date when="2008">2008</date><idno type="wicri:Area/Pmc/Corpus">000034</idno><idno type="wicri:Area/Pmc/Curation">000034</idno><idno type="wicri:Area/Pmc/Checkpoint">000442</idno><idno type="wicri:source">PubMed</idno><idno type="wicri:Area/PubMed/Corpus">002067</idno><idno type="wicri:Area/PubMed/Curation">002067</idno><idno type="wicri:Area/PubMed/Checkpoint">002223</idno><idno type="wicri:Area/Ncbi/Merge">002296</idno><idno type="wicri:Area/Ncbi/Curation">002296</idno><idno type="wicri:Area/Ncbi/Checkpoint">002296</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Medical Decision-Making Capacity in Cognitively Impaired Parkinson's Disease Patients Without Dementia</title><author><name sortKey="Martin, Roy C" sort="Martin, Roy C" uniqKey="Martin R" first="Roy C." last="Martin">Roy C. Martin</name><affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation></author><author><name sortKey="Okonkwo, Ozioma C" sort="Okonkwo, Ozioma C" uniqKey="Okonkwo O" first="Ozioma C." last="Okonkwo">Ozioma C. Okonkwo</name><affiliation wicri:level="2"><nlm:aff id="A3"> Department of Psychology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Department of Psychology, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation></author><author><name sortKey="Hill, Joni" sort="Hill, Joni" uniqKey="Hill J" first="Joni" last="Hill">Joni Hill</name><affiliation wicri:level="2"><nlm:aff id="A3"> Department of Psychology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Department of Psychology, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation></author><author><name sortKey="Griffith, H Randall" sort="Griffith, H Randall" uniqKey="Griffith H" first="H. Randall" last="Griffith">H. Randall Griffith</name><affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation></author><author><name sortKey="Triebel, Kristen" sort="Triebel, Kristen" uniqKey="Triebel K" first="Kristen" last="Triebel">Kristen Triebel</name><affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation></author><author><name sortKey="Bartolucci, Alfred" sort="Bartolucci, Alfred" uniqKey="Bartolucci A" first="Alfred" last="Bartolucci">Alfred Bartolucci</name><affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A4"> Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Department of Biostatistics, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation></author><author><name sortKey="Nicholas, Anthony P" sort="Nicholas, Anthony P" uniqKey="Nicholas A" first="Anthony P." last="Nicholas">Anthony P. Nicholas</name><affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A5"> Veterans Administration Medical Center, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Veterans Administration Medical Center, Birmingham</wicri:cityArea></affiliation></author><author><name sortKey="Watts, Ray L" sort="Watts, Ray L" uniqKey="Watts R" first="Ray L." last="Watts">Ray L. Watts</name><affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation></author><author><name sortKey="Stover, Natividad" sort="Stover, Natividad" uniqKey="Stover N" first="Natividad" last="Stover">Natividad Stover</name><affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation></author><author><name sortKey="Harrell, Lindy E" sort="Harrell, Lindy E" uniqKey="Harrell L" first="Lindy E." last="Harrell">Lindy E. Harrell</name><affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A4"> Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Department of Biostatistics, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A5"> Veterans Administration Medical Center, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Veterans Administration Medical Center, Birmingham</wicri:cityArea></affiliation></author><author><name sortKey="Clark, David" sort="Clark, David" uniqKey="Clark D" first="David" last="Clark">David Clark</name><affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A4"> Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Department of Biostatistics, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A5"> Veterans Administration Medical Center, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Veterans Administration Medical Center, Birmingham</wicri:cityArea></affiliation></author><author><name sortKey="Marson, Daniel C" sort="Marson, Daniel C" uniqKey="Marson D" first="Daniel C." last="Marson">Daniel C. Marson</name><affiliation wicri:level="2"><nlm:aff id="A1"> Department of Neurology, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Department of Neurology, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A2"> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham, AL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Alabama</region></placeName><wicri:cityArea> Alzheimer's Disease Research Center, University of Alabama at Birmingham, Birmingham</wicri:cityArea></affiliation></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><date when="2008">2008</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Case-Control Studies</term><term>Cognition Disorders (complications)</term><term>Cognition Disorders (psychology)</term><term>Decision Making (physiology)</term><term>Dementia (complications)</term><term>Female</term><term>Humans</term><term>Informed Consent (psychology)</term><term>Informed Consent (standards)</term><term>Male</term><term>Mental Competency</term><term>Middle Aged</term><term>Neuropsychological Tests</term><term>Parkinson Disease (complications)</term><term>Parkinson Disease (psychology)</term><term>Physician-Patient Relations</term><term>Retrospective Studies</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Cognition Disorders</term><term>Dementia</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Decision Making</term></keywords><keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Cognition Disorders</term><term>Informed Consent</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="standards" xml:lang="en"><term>Informed Consent</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Case-Control Studies</term><term>Female</term><term>Humans</term><term>Male</term><term>Mental Competency</term><term>Middle Aged</term><term>Neuropsychological Tests</term><term>Physician-Patient Relations</term><term>Retrospective Studies</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">Little is currently known about the higher order functional skills of patients with Parkinson disease and cognitive impairment. Medical decision-making capacity (MDC) was assessed in patients with Parkinson's disease (PD) with cognitive impairment and dementia. Participants were 16 patients with PD and cognitive impairment without dementia (PD-CIND), 16 patients with PD dementia (PDD), and 22 healthy older adults. All participants were administered the Capacity to Consent to Treatment Instrument (CCTI), a standardized capacity instrument assessing MDC under five different consent standards. Parametric and non-parametric statistical analyses were utilized to examine capacity performance on the consent standards. In addition, capacity outcomes (capable, marginally capable, or incapable outcomes) on the standards were identified for the two patient groups. Relative to controls, PD-CIND patients demonstrated significant impairment on the understanding treatment consent standard, clinically the most stringent CCTI standard. Relative to controls and PD-CIND patients, patients with PDD patients were impaired on the three clinical standards of <italic>understanding</italic>, <italic>reasoning</italic>, and <italic>appreciation</italic>. The findings suggest that impairment in decisional capacity is already present in cognitively impaired PD patients without dementia, and increases as these patients develop dementia. Clinicians and researchers should carefully assess decisional capacity in all PD patients with cognitive impairment.</p></div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Alabama</li></region></list><tree><country name="États-Unis"><region name="Alabama"><name sortKey="Martin, Roy C" sort="Martin, Roy C" uniqKey="Martin R" first="Roy C." last="Martin">Roy C. Martin</name></region><name sortKey="Bartolucci, Alfred" sort="Bartolucci, Alfred" uniqKey="Bartolucci A" first="Alfred" last="Bartolucci">Alfred Bartolucci</name><name sortKey="Bartolucci, Alfred" sort="Bartolucci, Alfred" uniqKey="Bartolucci A" first="Alfred" last="Bartolucci">Alfred Bartolucci</name><name sortKey="Clark, David" sort="Clark, David" uniqKey="Clark D" first="David" last="Clark">David Clark</name><name sortKey="Clark, David" sort="Clark, David" uniqKey="Clark D" first="David" last="Clark">David Clark</name><name sortKey="Clark, David" sort="Clark, David" uniqKey="Clark D" first="David" last="Clark">David Clark</name><name sortKey="Griffith, H Randall" sort="Griffith, H Randall" uniqKey="Griffith H" first="H. Randall" last="Griffith">H. Randall Griffith</name><name sortKey="Griffith, H Randall" sort="Griffith, H Randall" uniqKey="Griffith H" first="H. Randall" last="Griffith">H. Randall Griffith</name><name sortKey="Harrell, Lindy E" sort="Harrell, Lindy E" uniqKey="Harrell L" first="Lindy E." last="Harrell">Lindy E. Harrell</name><name sortKey="Harrell, Lindy E" sort="Harrell, Lindy E" uniqKey="Harrell L" first="Lindy E." last="Harrell">Lindy E. Harrell</name><name sortKey="Harrell, Lindy E" sort="Harrell, Lindy E" uniqKey="Harrell L" first="Lindy E." last="Harrell">Lindy E. Harrell</name><name sortKey="Hill, Joni" sort="Hill, Joni" uniqKey="Hill J" first="Joni" last="Hill">Joni Hill</name><name sortKey="Marson, Daniel C" sort="Marson, Daniel C" uniqKey="Marson D" first="Daniel C." last="Marson">Daniel C. Marson</name><name sortKey="Marson, Daniel C" sort="Marson, Daniel C" uniqKey="Marson D" first="Daniel C." last="Marson">Daniel C. Marson</name><name sortKey="Martin, Roy C" sort="Martin, Roy C" uniqKey="Martin R" first="Roy C." last="Martin">Roy C. Martin</name><name sortKey="Nicholas, Anthony P" sort="Nicholas, Anthony P" uniqKey="Nicholas A" first="Anthony P." last="Nicholas">Anthony P. Nicholas</name><name sortKey="Nicholas, Anthony P" sort="Nicholas, Anthony P" uniqKey="Nicholas A" first="Anthony P." last="Nicholas">Anthony P. Nicholas</name><name sortKey="Nicholas, Anthony P" sort="Nicholas, Anthony P" uniqKey="Nicholas A" first="Anthony P." last="Nicholas">Anthony P. Nicholas</name><name sortKey="Okonkwo, Ozioma C" sort="Okonkwo, Ozioma C" uniqKey="Okonkwo O" first="Ozioma C." last="Okonkwo">Ozioma C. Okonkwo</name><name sortKey="Stover, Natividad" sort="Stover, Natividad" uniqKey="Stover N" first="Natividad" last="Stover">Natividad Stover</name><name sortKey="Triebel, Kristen" sort="Triebel, Kristen" uniqKey="Triebel K" first="Kristen" last="Triebel">Kristen Triebel</name><name sortKey="Triebel, Kristen" sort="Triebel, Kristen" uniqKey="Triebel K" first="Kristen" last="Triebel">Kristen Triebel</name><name sortKey="Watts, Ray L" sort="Watts, Ray L" uniqKey="Watts R" first="Ray L." last="Watts">Ray L. Watts</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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