Movement Disorders (revue)

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Eyelid movements during blinking in patients with Parkinson's disease.

Identifieur interne : 001686 ( Ncbi/Checkpoint ); précédent : 001685; suivant : 001687

Eyelid movements during blinking in patients with Parkinson's disease.

Auteurs : Marko Korosec [Slovénie] ; Ignac Zidar ; Dik Reits ; Craig Evinger ; Frans Vanderwerf

Source :

RBID : pubmed:16685691

English descriptors

Abstract

We examined eyelid movements during spontaneous, voluntary, and trigeminal reflex blinks in 16 patients with mild to moderate Parkinson's disease (PD) off medication and 14 controls. Voluntary and reflex blink amplitudes tended to be smaller than normal for PD patients, whereas eyelid kinematics (amplitude-maximum velocity relationship) for all three blink types were normal. Spontaneous blink rate was less than normal for 10 patients and abnormally high for 6 patients. A significant positive correlation between spontaneous blink amplitude and blink rate was found. These observations suggest that PD modifies the gain of a premotor blink circuit shared by spontaneous, voluntary, and reflex blinks.

DOI: 10.1002/mds.20930
PubMed: 16685691


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pubmed:16685691

Le document en format XML

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<div type="abstract" xml:lang="en">We examined eyelid movements during spontaneous, voluntary, and trigeminal reflex blinks in 16 patients with mild to moderate Parkinson's disease (PD) off medication and 14 controls. Voluntary and reflex blink amplitudes tended to be smaller than normal for PD patients, whereas eyelid kinematics (amplitude-maximum velocity relationship) for all three blink types were normal. Spontaneous blink rate was less than normal for 10 patients and abnormally high for 6 patients. A significant positive correlation between spontaneous blink amplitude and blink rate was found. These observations suggest that PD modifies the gain of a premotor blink circuit shared by spontaneous, voluntary, and reflex blinks.</div>
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