Five-year follow-up study of hyperechogenicity of the substantia nigra in Parkinson's disease.
Identifieur interne : 001072 ( Ncbi/Checkpoint ); précédent : 001071; suivant : 001073Five-year follow-up study of hyperechogenicity of the substantia nigra in Parkinson's disease.
Auteurs : Daniela Berg [Allemagne] ; Berthold Merz ; Karlheinz Reiners ; Markus Naumann ; Georg BeckerSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2005.
English descriptors
- KwdEn :
- MESH :
- ultrasonography : Parkinson Disease, Substantia Nigra.
- Adult, Aged, Female, Follow-Up Studies, Humans, Male, Middle Aged, Severity of Illness Index.
Abstract
Using transcranial sonography, an area of hyperechogenicity at the substantia nigra (SN) may be detected as a typical marker in patients with Parkinson's disease (PD) as well as in approximately 9% of healthy subjects vulnerable to nigrostriatal impairment. In this longitudinal study, we provide evidence that the area of SN hyperechogenicity does not change in the course of PD. In conjunction with earlier findings in children and adolescents, this evidence indicates that, from late adolescence onward, this ultrasound finding is a trait marker for nigrostriatal vulnerability.
DOI: 10.1002/mds.20311
PubMed: 15486999
Affiliations:
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In this longitudinal study, we provide evidence that the area of SN hyperechogenicity does not change in the course of PD. In conjunction with earlier findings in children and adolescents, this evidence indicates that, from late adolescence onward, this ultrasound finding is a trait marker for nigrostriatal vulnerability.</div></front></TEI><affiliations><list><country><li>Allemagne</li></country><region><li>Bade-Wurtemberg</li><li>District de Tübingen</li></region><settlement><li>Tübingen</li></settlement></list><tree><noCountry><name sortKey="Becker, Georg" sort="Becker, Georg" uniqKey="Becker G" first="Georg" last="Becker">Georg Becker</name><name sortKey="Merz, Berthold" sort="Merz, Berthold" uniqKey="Merz B" first="Berthold" last="Merz">Berthold Merz</name><name sortKey="Naumann, Markus" sort="Naumann, Markus" uniqKey="Naumann M" first="Markus" last="Naumann">Markus Naumann</name><name sortKey="Reiners, Karlheinz" sort="Reiners, Karlheinz" uniqKey="Reiners K" first="Karlheinz" last="Reiners">Karlheinz Reiners</name></noCountry><country name="Allemagne"><region name="Bade-Wurtemberg"><name sortKey="Berg, Daniela" sort="Berg, Daniela" uniqKey="Berg D" first="Daniela" last="Berg">Daniela Berg</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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