Factor analysis of the motor section of the unified Parkinson's disease rating scale during the off-state.
Identifieur interne : 000077 ( Ncbi/Checkpoint ); précédent : 000076; suivant : 000078Factor analysis of the motor section of the unified Parkinson's disease rating scale during the off-state.
Auteurs : G T Stebbins [États-Unis] ; C G Goetz ; A E Lang ; E. CuboSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 1999.
English descriptors
- KwdEn :
- MESH :
- diagnosis : Parkinson Disease.
- standards : Neurologic Examination, Psychometrics.
- Aged, Disease Progression, Factor Analysis, Statistical, Female, Humans, Male, Middle Aged, Reproducibility of Results, Severity of Illness Index.
Abstract
Determination of a scale's factor structure requires a two-part process: (1) an initial examination of the factor structure using a sample of individuals with the condition of interest, and (2) repeated examinations of the factor structure using the same analytic methods but applied to independent samples of individuals with the condition of interest who contribute unique variability to the scale measurement. In a previous study, we performed an initial investigation of the factor structure of the Motor Examination section of the Unified Parkinson's Disease Rating Scale (UPDRS). We used a sample of 294 consecutive patients with idiopathic Parkinson's disease (PD) assessed while in the on-state and identified six clinically distinct factors. In the present study, we performed a confirmatory investigation of the factor structure and analysis of the internal consistency of the UPDRS in a new sample of 200 consecutive PD patients who were assessed while in the off-state. Factor analysis again revealed six factors with identical item loadings as those obtained from examinations of patients in the on-state. Estimates of internal consistency were comparable in the off- and on-state examinations. These results indicate that the Motor Examination section of the UPDRS has a stable factor structure and high internal consistency across off- and on-state examinations.
PubMed: 10435494
Affiliations:
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pubmed:10435494Le document en format XML
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Cubo</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1999">1999</date><idno type="RBID">pubmed:10435494</idno><idno type="pmid">10435494</idno><idno type="wicri:Area/PubMed/Corpus">004174</idno><idno type="wicri:Area/PubMed/Curation">004174</idno><idno type="wicri:Area/PubMed/Checkpoint">004209</idno><idno type="wicri:Area/Ncbi/Merge">000077</idno><idno type="wicri:Area/Ncbi/Curation">000077</idno><idno type="wicri:Area/Ncbi/Checkpoint">000077</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Factor analysis of the motor section of the unified Parkinson's disease rating scale during the off-state.</title><author><name sortKey="Stebbins, G T" sort="Stebbins, G T" uniqKey="Stebbins G" first="G T" last="Stebbins">G T Stebbins</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurological Sciences, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois 60612, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurological Sciences, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois 60612</wicri:regionArea><wicri:noRegion>Illinois 60612</wicri:noRegion></affiliation></author><author><name sortKey="Goetz, C G" sort="Goetz, C G" uniqKey="Goetz C" first="C G" last="Goetz">C G Goetz</name></author><author><name sortKey="Lang, A E" sort="Lang, A E" uniqKey="Lang A" first="A E" last="Lang">A E Lang</name></author><author><name sortKey="Cubo, E" sort="Cubo, E" uniqKey="Cubo E" first="E" last="Cubo">E. Cubo</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="ISSN">0885-3185</idno><imprint><date when="1999" type="published">1999</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Disease Progression</term><term>Factor Analysis, Statistical</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Neurologic Examination (standards)</term><term>Parkinson Disease (diagnosis)</term><term>Psychometrics (standards)</term><term>Reproducibility of Results</term><term>Severity of Illness Index</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="standards" xml:lang="en"><term>Neurologic Examination</term><term>Psychometrics</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Disease Progression</term><term>Factor Analysis, Statistical</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Reproducibility of Results</term><term>Severity of Illness Index</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Determination of a scale's factor structure requires a two-part process: (1) an initial examination of the factor structure using a sample of individuals with the condition of interest, and (2) repeated examinations of the factor structure using the same analytic methods but applied to independent samples of individuals with the condition of interest who contribute unique variability to the scale measurement. In a previous study, we performed an initial investigation of the factor structure of the Motor Examination section of the Unified Parkinson's Disease Rating Scale (UPDRS). We used a sample of 294 consecutive patients with idiopathic Parkinson's disease (PD) assessed while in the on-state and identified six clinically distinct factors. In the present study, we performed a confirmatory investigation of the factor structure and analysis of the internal consistency of the UPDRS in a new sample of 200 consecutive PD patients who were assessed while in the off-state. Factor analysis again revealed six factors with identical item loadings as those obtained from examinations of patients in the on-state. Estimates of internal consistency were comparable in the off- and on-state examinations. These results indicate that the Motor Examination section of the UPDRS has a stable factor structure and high internal consistency across off- and on-state examinations.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country></list><tree><noCountry><name sortKey="Cubo, E" sort="Cubo, E" uniqKey="Cubo E" first="E" last="Cubo">E. Cubo</name><name sortKey="Goetz, C G" sort="Goetz, C G" uniqKey="Goetz C" first="C G" last="Goetz">C G Goetz</name><name sortKey="Lang, A E" sort="Lang, A E" uniqKey="Lang A" first="A E" last="Lang">A E Lang</name></noCountry><country name="États-Unis"><noRegion><name sortKey="Stebbins, G T" sort="Stebbins, G T" uniqKey="Stebbins G" first="G T" last="Stebbins">G T Stebbins</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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