Early detection of probable idiopathic Parkinson's disease: II. A prospective application of a diagnostic test battery.
Identifieur interne : 007135 ( Main/Merge ); précédent : 007134; suivant : 007136Early detection of probable idiopathic Parkinson's disease: II. A prospective application of a diagnostic test battery.
Auteurs : E B Montgomery [États-Unis] ; K. Lyons ; W C KollerSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2000.
English descriptors
- KwdEn :
- Adult, Aged, Aged, 80 and over, Diagnosis, Differential, Female, Humans, Male, Middle Aged, Neurologic Examination (statistics & numerical data), Parkinson Disease (diagnosis), Parkinson Disease (psychology), Personality Inventory (statistics & numerical data), Prospective Studies, Psychometrics, Reproducibility of Results.
- MESH :
- diagnosis : Parkinson Disease.
- psychology : Parkinson Disease.
- statistics & numerical data : Neurologic Examination, Personality Inventory.
- Adult, Aged, Aged, 80 and over, Diagnosis, Differential, Female, Humans, Male, Middle Aged, Prospective Studies, Psychometrics, Reproducibility of Results.
Abstract
We developed a battery of tests, incorporating motor function, olfaction, and mood, that distinguishes between early mild, probable idiopathic Parkinson's disease (iPD), and normal control subjects. Here, we determined the PD Battery's ability to prospectively identify which patients with symptoms and signs suggestive of, but not yet diagnostic of, iPD who would subsequently be diagnosed as having iPD. Of 212 enrolled patients, 194 have been followed for at least 1 year. Among these 194, 59 were diagnosed with iPD, 40 as neurologically normal, and the remaining 106 with other neurologic conditions such as essential tremor. The test battery was 92% specific and 68% sensitive for iPD. The area under the Receiver Operating Characteristics curve was 0.88 for predicting which participants would subsequently be diagnosed as having iPD or as being neurologically normal.
PubMed: 10830411
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pubmed:10830411Le document en format XML
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Lyons</name></author><author><name sortKey="Koller, W C" sort="Koller, W C" uniqKey="Koller W" first="W C" last="Koller">W C Koller</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2000">2000</date><idno type="RBID">pubmed:10830411</idno><idno type="pmid">10830411</idno><idno type="wicri:Area/PubMed/Corpus">003F81</idno><idno type="wicri:Area/PubMed/Curation">003F81</idno><idno type="wicri:Area/PubMed/Checkpoint">003F92</idno><idno type="wicri:Area/Ncbi/Merge">000270</idno><idno type="wicri:Area/Ncbi/Curation">000270</idno><idno type="wicri:Area/Ncbi/Checkpoint">000270</idno><idno type="wicri:doubleKey">0885-3185:2000:Montgomery E:early:detection:of</idno><idno type="wicri:Area/Main/Merge">007135</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Early detection of probable idiopathic Parkinson's disease: II. A prospective application of a diagnostic test battery.</title><author><name sortKey="Montgomery, E B" sort="Montgomery, E B" uniqKey="Montgomery E" first="E B" last="Montgomery">E B Montgomery</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, Lerner Research Institute, Cleveland Clinic Foundation, Ohio 44195, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurology, Lerner Research Institute, Cleveland Clinic Foundation, Ohio 44195</wicri:regionArea><wicri:noRegion>Ohio 44195</wicri:noRegion></affiliation></author><author><name sortKey="Lyons, K" sort="Lyons, K" uniqKey="Lyons K" first="K" last="Lyons">K. Lyons</name></author><author><name sortKey="Koller, W C" sort="Koller, W C" uniqKey="Koller W" first="W C" last="Koller">W C Koller</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="ISSN">0885-3185</idno><imprint><date when="2000" type="published">2000</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Diagnosis, Differential</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Neurologic Examination (statistics & numerical data)</term><term>Parkinson Disease (diagnosis)</term><term>Parkinson Disease (psychology)</term><term>Personality Inventory (statistics & numerical data)</term><term>Prospective Studies</term><term>Psychometrics</term><term>Reproducibility of Results</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Neurologic Examination</term><term>Personality Inventory</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Diagnosis, Differential</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Prospective Studies</term><term>Psychometrics</term><term>Reproducibility of Results</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We developed a battery of tests, incorporating motor function, olfaction, and mood, that distinguishes between early mild, probable idiopathic Parkinson's disease (iPD), and normal control subjects. Here, we determined the PD Battery's ability to prospectively identify which patients with symptoms and signs suggestive of, but not yet diagnostic of, iPD who would subsequently be diagnosed as having iPD. Of 212 enrolled patients, 194 have been followed for at least 1 year. Among these 194, 59 were diagnosed with iPD, 40 as neurologically normal, and the remaining 106 with other neurologic conditions such as essential tremor. The test battery was 92% specific and 68% sensitive for iPD. The area under the Receiver Operating Characteristics curve was 0.88 for predicting which participants would subsequently be diagnosed as having iPD or as being neurologically normal.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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