Movement Disorders (revue)

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Irresistible onset of sleep during acute levodopa challenge in a patient with multiple system atrophy: Placebo-controlled, polysomnographic case report

Identifieur interne : 006E70 ( Main/Merge ); précédent : 006E69; suivant : 006E71

Irresistible onset of sleep during acute levodopa challenge in a patient with multiple system atrophy: Placebo-controlled, polysomnographic case report

Auteurs : Birgit Högl [Autriche] ; Md. Klaus Seppi [Autriche] ; Elisabeth Brandauer [Autriche] ; Gregor Wenning [Autriche] ; Werner Poewe [Autriche]

Source :

RBID : Pascal:02-0176261

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English descriptors

Abstract

A 67-year-old male patient with clinically probable multiple system atrophy developed severe reproducible sleepiness and irresistible onset of sleep during an acute levodopa (L-dopa) challenge. In a placebo-controlled, double-blind study of acute L-dopa challenge, videopolysomnography revealed multiple episodes of non-rapid eye movement sleep 60 minutes after L-dopa and none following placebo. These observations suggest the irresistible sleep can also he induced by L-dopa and also in patients with atypical parkinsonism. Disorder Society.

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Pascal:02-0176261

Le document en format XML

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<div type="abstract" xml:lang="en">A 67-year-old male patient with clinically probable multiple system atrophy developed severe reproducible sleepiness and irresistible onset of sleep during an acute levodopa (L-dopa) challenge. In a placebo-controlled, double-blind study of acute L-dopa challenge, videopolysomnography revealed multiple episodes of non-rapid eye movement sleep 60 minutes after L-dopa and none following placebo. These observations suggest the irresistible sleep can also he induced by L-dopa and also in patients with atypical parkinsonism. Disorder Society.</div>
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