Treatment of dystonic clenched fist with botulinum toxin
Identifieur interne : 006B43 ( Main/Merge ); précédent : 006B42; suivant : 006B44Treatment of dystonic clenched fist with botulinum toxin
Auteurs : Carla Cordivari [Royaume-Uni] ; V. Peter Misra [Royaume-Uni] ; Santiago Catania [Royaume-Uni] ; Andrew Lees (neurologue) [Royaume-Uni]Source :
- Movement Disorders [ 0885-3185 ] ; 2001-09.
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Abstract
Fourteen patients with “dystonic clenched fist” (three with Corticobasal Ganglionic Degeneration, seven with Parkinson's disease, and four with Dystonic‐Complex Regional Pain Syndrome) were treated with botulinum toxin A (BTXA, Dysport®). The muscles involved were identified by the hand posture and EMG activity recorded at rest and during active and passive flexion/extension movements of the finger and wrist. EMG was useful in distinguishing between muscle contraction and underlying contractures and to determine the dosage of BTX. All patients had some degree of flexion at the proximal metacarpophalangeal joints and required injections into the lumbricals. The response in patients depended on the severity of the deformity and the degree of contracture. All patients had significant benefit to pain, with accompanying muscle relaxation, and palmar infection, when present, was eradicated. Four patients with Parkinson's disease and one patient with Dystonia‐Complex Regional Pain Syndrome obtained functional benefit. © 2001 Movement Disorder Society.
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DOI: 10.1002/mds.1186
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Peter Misra</name></author><author><name sortKey="Catania, Santiago" sort="Catania, Santiago" uniqKey="Catania S" first="Santiago" last="Catania">Santiago Catania</name></author><author><name sortKey="Lees, Andrew J" sort="Lees, Andrew J" uniqKey="Lees A" first="Andrew J." last="Lees">Andrew Lees (neurologue)</name><affiliation><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName><orgName>National Hospital for Neurology and Neurosurgery</orgName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:1BED386F4239A9E11E29C52CAFF1728B02CF06AE</idno><date when="2001" year="2001">2001</date><idno type="doi">10.1002/mds.1186</idno><idno type="url">https://api.istex.fr/document/1BED386F4239A9E11E29C52CAFF1728B02CF06AE/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">001E43</idno><idno type="wicri:Area/Istex/Curation">001E43</idno><idno type="wicri:Area/Istex/Checkpoint">002E88</idno><idno type="wicri:doubleKey">0885-3185:2001:Cordivari C:treatment:of:dystonic</idno><idno type="wicri:Area/Main/Merge">006B43</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Treatment of dystonic clenched fist with botulinum toxin</title><author><name sortKey="Cordivari, Carla" sort="Cordivari, Carla" uniqKey="Cordivari C" first="Carla" last="Cordivari">Carla Cordivari</name><affiliation wicri:level="3"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Clinical Neurophysiology, The National Hospital for Neurology and Neurosurgery, Queen Square, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Reta Lila Weston Institute of Neurological Studies, University College of London</wicri:regionArea><wicri:noRegion>University College of London</wicri:noRegion></affiliation></author><author><name sortKey="Misra, V Peter" sort="Misra, V Peter" uniqKey="Misra V" first="V. 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Peter Misra</name><affiliation wicri:level="3"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Clinical Neurophysiology, The National Hospital for Neurology and Neurosurgery, Queen Square, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Catania, Santiago" sort="Catania, Santiago" uniqKey="Catania S" first="Santiago" last="Catania">Santiago Catania</name><affiliation wicri:level="3"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Clinical Neurophysiology, The National Hospital for Neurology and Neurosurgery, Queen Square, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Lees, Andrew J" sort="Lees, Andrew J" uniqKey="Lees A" first="Andrew J." last="Lees">Andrew Lees (neurologue)</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Reta Lila Weston Institute of Neurological Studies, University College of London</wicri:regionArea><wicri:noRegion>University College of London</wicri:noRegion><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName><orgName>National Hospital for Neurology and Neurosurgery</orgName></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>John Wiley & Sons, Inc.</publisher><pubPlace>New York</pubPlace><date type="published" when="2001-09">2001-09</date><biblScope unit="vol">16</biblScope><biblScope unit="issue">5</biblScope><biblScope unit="page" from="907">907</biblScope><biblScope unit="page" to="913">913</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">1BED386F4239A9E11E29C52CAFF1728B02CF06AE</idno><idno type="DOI">10.1002/mds.1186</idno><idno type="ArticleID">MDS1186</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>EMG</term><term>Parkinson's disease</term><term>botulinum toxin</term><term>corticobasal degeneration</term><term>dystonia associated with complex regional pain syndrome</term><term>dystonic clenched fist</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Fourteen patients with “dystonic clenched fist” (three with Corticobasal Ganglionic Degeneration, seven with Parkinson's disease, and four with Dystonic‐Complex Regional Pain Syndrome) were treated with botulinum toxin A (BTXA, Dysport®). The muscles involved were identified by the hand posture and EMG activity recorded at rest and during active and passive flexion/extension movements of the finger and wrist. EMG was useful in distinguishing between muscle contraction and underlying contractures and to determine the dosage of BTX. All patients had some degree of flexion at the proximal metacarpophalangeal joints and required injections into the lumbricals. The response in patients depended on the severity of the deformity and the degree of contracture. All patients had significant benefit to pain, with accompanying muscle relaxation, and palmar infection, when present, was eradicated. Four patients with Parkinson's disease and one patient with Dystonia‐Complex Regional Pain Syndrome obtained functional benefit. © 2001 Movement Disorder Society.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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