Stiff leg syndrome: case report.
Identifieur interne : 006939 ( Main/Merge ); précédent : 006938; suivant : 006940Stiff leg syndrome: case report.
Auteurs : M E Gürol [Turquie] ; M. Ertas ; H A Hanagasi ; H A Sahin ; G. Gürsoy ; M. EmreSource :
- Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2001.
English descriptors
- KwdEn :
- Adult, Autoantibodies (blood), Diabetes Mellitus, Type 1 (complications), Electric Stimulation, Electromyography, Female, Glutamate Decarboxylase (immunology), Humans, Hyperthyroidism (complications), Leg (physiopathology), Muscle Spasticity (etiology), Muscle Spasticity (physiopathology), Stiff-Person Syndrome (diagnosis), Stiff-Person Syndrome (physiopathology).
- MESH :
- chemical , blood : Autoantibodies.
- complications : Diabetes Mellitus, Type 1, Hyperthyroidism.
- diagnosis : Stiff-Person Syndrome.
- etiology : Muscle Spasticity.
- chemical , immunology : Glutamate Decarboxylase.
- physiopathology : Leg, Muscle Spasticity, Stiff-Person Syndrome.
- Adult, Electric Stimulation, Electromyography, Female, Humans.
Abstract
We report on a 28-year-old woman with insulin-resistant diabetes mellitus with a 5-year history of progressive stiffness and painful spasms of the right leg, exaggerated by sudden auditory and tactile stimuli or by emotional stress. There were no signs of truncal rigidity or exaggerated lumbar lordosis. Anti-glutamic acid decarboxylase antibodies were positive in her serum. She improved substantially with clonazepam 4 mg/day. She presented with electrophysiological findings not previously reported in stiff leg syndrome, which may suggest increased inhibition in the uninvolved upper extremities.
PubMed: 11748762
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pubmed:11748762Le document en format XML
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Ertas</name></author><author><name sortKey="Hanagasi, H A" sort="Hanagasi, H A" uniqKey="Hanagasi H" first="H A" last="Hanagasi">H A Hanagasi</name></author><author><name sortKey="Sahin, H A" sort="Sahin, H A" uniqKey="Sahin H" first="H A" last="Sahin">H A Sahin</name></author><author><name sortKey="Gursoy, G" sort="Gursoy, G" uniqKey="Gursoy G" first="G" last="Gürsoy">G. Gürsoy</name></author><author><name sortKey="Emre, M" sort="Emre, M" uniqKey="Emre M" first="M" last="Emre">M. 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Ertas</name></author><author><name sortKey="Hanagasi, H A" sort="Hanagasi, H A" uniqKey="Hanagasi H" first="H A" last="Hanagasi">H A Hanagasi</name></author><author><name sortKey="Sahin, H A" sort="Sahin, H A" uniqKey="Sahin H" first="H A" last="Sahin">H A Sahin</name></author><author><name sortKey="Gursoy, G" sort="Gursoy, G" uniqKey="Gursoy G" first="G" last="Gürsoy">G. Gürsoy</name></author><author><name sortKey="Emre, M" sort="Emre, M" uniqKey="Emre M" first="M" last="Emre">M. Emre</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="ISSN">0885-3185</idno><imprint><date when="2001" type="published">2001</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Autoantibodies (blood)</term><term>Diabetes Mellitus, Type 1 (complications)</term><term>Electric Stimulation</term><term>Electromyography</term><term>Female</term><term>Glutamate Decarboxylase (immunology)</term><term>Humans</term><term>Hyperthyroidism (complications)</term><term>Leg (physiopathology)</term><term>Muscle Spasticity (etiology)</term><term>Muscle Spasticity (physiopathology)</term><term>Stiff-Person Syndrome (diagnosis)</term><term>Stiff-Person Syndrome (physiopathology)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Autoantibodies</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Diabetes Mellitus, Type 1</term><term>Hyperthyroidism</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Stiff-Person Syndrome</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Muscle Spasticity</term></keywords><keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>Glutamate Decarboxylase</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Leg</term><term>Muscle Spasticity</term><term>Stiff-Person Syndrome</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Electric Stimulation</term><term>Electromyography</term><term>Female</term><term>Humans</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We report on a 28-year-old woman with insulin-resistant diabetes mellitus with a 5-year history of progressive stiffness and painful spasms of the right leg, exaggerated by sudden auditory and tactile stimuli or by emotional stress. There were no signs of truncal rigidity or exaggerated lumbar lordosis. Anti-glutamic acid decarboxylase antibodies were positive in her serum. She improved substantially with clonazepam 4 mg/day. She presented with electrophysiological findings not previously reported in stiff leg syndrome, which may suggest increased inhibition in the uninvolved upper extremities.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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