MovDisordV3, Main, Merge, bibRecord, 005872

Punding in Parkinson's disease: Its relation to the dopamine dysregulation syndrome

Identifieur interne : 005872 ( Main/Merge ); précédent : 005871; suivant : 005873

Punding in Parkinson's disease: Its relation to the dopamine dysregulation syndrome

Auteurs : Andrew H. Evans [Royaume-Uni] ; Regina Katzenschlager [Royaume-Uni] ; Dominic Paviour [Royaume-Uni] ; John D. O'Sullivan [Australie] ; Silke Appel [Royaume-Uni] ; Andrew D. Lawrence [Royaume-Uni] ; Andrew Lees (neurologue) [Royaume-Uni]

Source :

Movement disorders [ 0885-3185 ] ; 2004.

RBID : Pascal:04-0261629

Descripteurs français

Pascal (Inist)
- Parkinson maladie, Dopamine, Système nerveux pathologie, Catécholamine, Stimulant dopaminergique.

English descriptors

KwdEn :
- Catecholamine, Dopamine, Dopamine agonist, Nervous system diseases, Parkinson disease.

Abstract

Punding is a term that was coined originally to describe complex prolonged, purposeless, and stereotyped behaviour in chronic amphetamine users. A structured interview of 50 patients with higher dopamine replacement therapy requirements (>800 levodopa equivalent units/day) from 123 unselected patients with Parkinson's disease (PD) from a PD clinic identified 17 (14%) patients with punding. Punding was acknowledged as disruptive and unproductive by the patients themselves, but forcible attempts by family to interrupt the behaviour led to irritability and dysphoria. Punding was associated with very high doses of dopamine replacement therapy often related to a pattern of chronic inappropriate overuse of dopaminergic medication. We believe that this is an underreported, socially disabling phenomenon that is commonly associated with the syndrome of dopamine dysregulation and is phenomenologically distinct from both obsessive-compulsive disorder and mania.

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Pascal:04-0261629

Le document en format XML

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<term>Parkinson disease</term>
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<keywords scheme="Pascal" xml:lang="fr"><term>Parkinson maladie</term>
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<front><div type="abstract" xml:lang="en">Punding is a term that was coined originally to describe complex prolonged, purposeless, and stereotyped behaviour in chronic amphetamine users. A structured interview of 50 patients with higher dopamine replacement therapy requirements (>800 levodopa equivalent units/day) from 123 unselected patients with Parkinson's disease (PD) from a PD clinic identified 17 (14%) patients with punding. Punding was acknowledged as disruptive and unproductive by the patients themselves, but forcible attempts by family to interrupt the behaviour led to irritability and dysphoria. Punding was associated with very high doses of dopamine replacement therapy often related to a pattern of chronic inappropriate overuse of dopaminergic medication. We believe that this is an underreported, socially disabling phenomenon that is commonly associated with the syndrome of dopamine dysregulation and is phenomenologically distinct from both obsessive-compulsive disorder and mania.</div>
</front>
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<name sortKey="Evans, Andrew H" sort="Evans, Andrew H" uniqKey="Evans A" first="Andrew H." last="Evans">Andrew H. Evans</name>
<name sortKey="Katzenschlager, Regina" sort="Katzenschlager, Regina" uniqKey="Katzenschlager R" first="Regina" last="Katzenschlager">Regina Katzenschlager</name>
<name sortKey="Katzenschlager, Regina" sort="Katzenschlager, Regina" uniqKey="Katzenschlager R" first="Regina" last="Katzenschlager">Regina Katzenschlager</name>
<name sortKey="Lawrence, Andrew D" sort="Lawrence, Andrew D" uniqKey="Lawrence A" first="Andrew D." last="Lawrence">Andrew D. Lawrence</name>
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<name sortKey="Paviour, Dominic" sort="Paviour, Dominic" uniqKey="Paviour D" first="Dominic" last="Paviour">Dominic Paviour</name>
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<country name="Australie"><noRegion><name sortKey="O Sullivan, John D" sort="O Sullivan, John D" uniqKey="O Sullivan J" first="John D." last="O'Sullivan">John D. O'Sullivan</name>
</noRegion>
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   |texte=   Punding in Parkinson's disease: Its relation to the dopamine dysregulation syndrome
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	Movement Disorders (revue)
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Movement Disorders (revue)

Punding in Parkinson's disease: Its relation to the dopamine dysregulation syndrome

Punding in Parkinson's disease: Its relation to the dopamine dysregulation syndrome

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