Test–retest reliability of UPDRS‐III, dyskinesia scales, and timed motor tests in patients with advanced Parkinson's disease: An argument against multiple baseline assessments
Identifieur interne : 005468 ( Main/Merge ); précédent : 005467; suivant : 005469Test–retest reliability of UPDRS‐III, dyskinesia scales, and timed motor tests in patients with advanced Parkinson's disease: An argument against multiple baseline assessments
Auteurs : Leo Verhagen Metman [États-Unis] ; Brian Myre [États-Unis] ; Niek Verwey [États-Unis] ; Sharon Hassin-Baer [Israël] ; Jean Arzbaecher [États-Unis] ; Diane Sierens [États-Unis] ; Roy Bakay [États-Unis]Source :
- Movement Disorders [ 0885-3185 ] ; 2004-09.
English descriptors
- KwdEn :
- MESH :
- complications : Parkinson Disease.
- diagnosis : Dyskinesias, Parkinson Disease.
- Female, Humans, Male, Middle Aged, Psychomotor Performance, Questionnaires, Reproducibility of Results, Time Factors.
Abstract
The primary objective of this study was to assess the intra‐rater reliability of the motor section of the Unified Parkinson's Disease Rating Scale (UPDRS‐III) in patients with advanced Parkinson's disease (PD). The secondary objective was to assess the intra‐rater reliability of standard timed motor tests and dyskinesia scales to determine the necessity of multiple baseline core evaluations before surgery for PD. We carried out two standardized preoperative core evaluations of patients with advanced PD scheduled to undergo deep brain stimulation. Patients were examined in the defined off and on conditions by the same rater. UPDRS‐III, timed tests, and dyskinesia scores from the two evaluations were compared using Wilcoxon Signed Ranks tests and intraclass correlation coefficients (ICC). Differences in UPDRS‐III scores for the two visits were clinically and statistically nonsignificant, and the ICC was 0.9. Similarly, there were no significant differences in timed motor tests or dyskinesia scores, with a median ICC of 0.8. The results indicate that previous findings of high test–retest reliability of UPDRS‐III in early untreated PD patients can now be extended to those with advanced disease complicated by motor fluctuations. In addition, test–retest reliability of dyskinesia scales and timed motor tests was high. Taken together, these findings challenge the need for multiple baseline assessments as currently stipulated in core assessment protocols for surgical intervention in PD. © 2004 Movement Disorder Society
Url:
DOI: 10.1002/mds.20101
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 001907
- to stream Istex, to step Curation: 001907
- to stream Istex, to step Checkpoint: 002491
- to stream PubMed, to step Corpus: 003350
- to stream PubMed, to step Curation: 003350
- to stream PubMed, to step Checkpoint: 003286
- to stream Ncbi, to step Merge: 000F38
- to stream Ncbi, to step Curation: 000F38
- to stream Ncbi, to step Checkpoint: 000F38
Links to Exploration step
ISTEX:486DDEEC3D4B55800E3CC8D678506F1F22E5377ALe document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Test–retest reliability of UPDRS‐III, dyskinesia scales, and timed motor tests in patients with advanced Parkinson's disease: An argument against multiple baseline assessments</title><author><name sortKey="Metman, Leo Verhagen" sort="Metman, Leo Verhagen" uniqKey="Metman L" first="Leo Verhagen" last="Metman">Leo Verhagen Metman</name></author><author><name sortKey="Myre, Brian" sort="Myre, Brian" uniqKey="Myre B" first="Brian" last="Myre">Brian Myre</name></author><author><name sortKey="Verwey, Niek" sort="Verwey, Niek" uniqKey="Verwey N" first="Niek" last="Verwey">Niek Verwey</name></author><author><name sortKey="Hassin Aer, Sharon" sort="Hassin Aer, Sharon" uniqKey="Hassin Aer S" first="Sharon" last="Hassin-Baer">Sharon Hassin-Baer</name></author><author><name sortKey="Arzbaecher, Jean" sort="Arzbaecher, Jean" uniqKey="Arzbaecher J" first="Jean" last="Arzbaecher">Jean Arzbaecher</name></author><author><name sortKey="Sierens, Diane" sort="Sierens, Diane" uniqKey="Sierens D" first="Diane" last="Sierens">Diane Sierens</name></author><author><name sortKey="Bakay, Roy" sort="Bakay, Roy" uniqKey="Bakay R" first="Roy" last="Bakay">Roy Bakay</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:486DDEEC3D4B55800E3CC8D678506F1F22E5377A</idno><date when="2004" year="2004">2004</date><idno type="doi">10.1002/mds.20101</idno><idno type="url">https://api.istex.fr/document/486DDEEC3D4B55800E3CC8D678506F1F22E5377A/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">001907</idno><idno type="wicri:Area/Istex/Curation">001907</idno><idno type="wicri:Area/Istex/Checkpoint">002491</idno><idno type="wicri:doubleKey">0885-3185:2004:Metman L:test:retest:reliability</idno><idno type="wicri:source">PubMed</idno><idno type="RBID">pubmed:15372601</idno><idno type="wicri:Area/PubMed/Corpus">003350</idno><idno type="wicri:Area/PubMed/Curation">003350</idno><idno type="wicri:Area/PubMed/Checkpoint">003286</idno><idno type="wicri:Area/Ncbi/Merge">000F38</idno><idno type="wicri:Area/Ncbi/Curation">000F38</idno><idno type="wicri:Area/Ncbi/Checkpoint">000F38</idno><idno type="wicri:doubleKey">0885-3185:2004:Metman L:test:retest:reliability</idno><idno type="wicri:Area/Main/Merge">005468</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Test–retest reliability of UPDRS‐III, dyskinesia scales, and timed motor tests in patients with advanced Parkinson's disease: An argument against multiple baseline assessments</title><author><name sortKey="Metman, Leo Verhagen" sort="Metman, Leo Verhagen" uniqKey="Metman L" first="Leo Verhagen" last="Metman">Leo Verhagen Metman</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Myre, Brian" sort="Myre, Brian" uniqKey="Myre B" first="Brian" last="Myre">Brian Myre</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Verwey, Niek" sort="Verwey, Niek" uniqKey="Verwey N" first="Niek" last="Verwey">Niek Verwey</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Hassin Aer, Sharon" sort="Hassin Aer, Sharon" uniqKey="Hassin Aer S" first="Sharon" last="Hassin-Baer">Sharon Hassin-Baer</name><affiliation wicri:level="1"><country xml:lang="fr">Israël</country><wicri:regionArea>Department of Neurology, Chaim Sheba Medical Center, Tel‐Hashomer</wicri:regionArea><wicri:noRegion>Tel‐Hashomer</wicri:noRegion></affiliation></author><author><name sortKey="Arzbaecher, Jean" sort="Arzbaecher, Jean" uniqKey="Arzbaecher J" first="Jean" last="Arzbaecher">Jean Arzbaecher</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Chicago Institute of Neurosurgery and Neuroresearch, Chicago, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Sierens, Diane" sort="Sierens, Diane" uniqKey="Sierens D" first="Diane" last="Sierens">Diane Sierens</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Chicago Institute of Neurosurgery and Neuroresearch, Chicago, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Bakay, Roy" sort="Bakay, Roy" uniqKey="Bakay R" first="Roy" last="Bakay">Roy Bakay</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Chicago Institute of Neurosurgery and Neuroresearch, Chicago, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2004-09">2004-09</date><biblScope unit="vol">19</biblScope><biblScope unit="issue">9</biblScope><biblScope unit="page" from="1079">1079</biblScope><biblScope unit="page" to="1084">1084</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">486DDEEC3D4B55800E3CC8D678506F1F22E5377A</idno><idno type="DOI">10.1002/mds.20101</idno><idno type="ArticleID">MDS20101</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>CAPIT</term><term>CAPSIT</term><term>Dyskinesias (diagnosis)</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Parkinson Disease (complications)</term><term>Parkinson Disease (diagnosis)</term><term>Parkinson's disease</term><term>Psychomotor Performance</term><term>Questionnaires</term><term>Reproducibility of Results</term><term>Time Factors</term><term>UPDRS</term><term>test–retest reliability</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Dyskinesias</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Psychomotor Performance</term><term>Questionnaires</term><term>Reproducibility of Results</term><term>Time Factors</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The primary objective of this study was to assess the intra‐rater reliability of the motor section of the Unified Parkinson's Disease Rating Scale (UPDRS‐III) in patients with advanced Parkinson's disease (PD). The secondary objective was to assess the intra‐rater reliability of standard timed motor tests and dyskinesia scales to determine the necessity of multiple baseline core evaluations before surgery for PD. We carried out two standardized preoperative core evaluations of patients with advanced PD scheduled to undergo deep brain stimulation. Patients were examined in the defined off and on conditions by the same rater. UPDRS‐III, timed tests, and dyskinesia scores from the two evaluations were compared using Wilcoxon Signed Ranks tests and intraclass correlation coefficients (ICC). Differences in UPDRS‐III scores for the two visits were clinically and statistically nonsignificant, and the ICC was 0.9. Similarly, there were no significant differences in timed motor tests or dyskinesia scores, with a median ICC of 0.8. The results indicate that previous findings of high test–retest reliability of UPDRS‐III in early untreated PD patients can now be extended to those with advanced disease complicated by motor fluctuations. In addition, test–retest reliability of dyskinesia scales and timed motor tests was high. Taken together, these findings challenge the need for multiple baseline assessments as currently stipulated in core assessment protocols for surgical intervention in PD. © 2004 Movement Disorder Society</div></front></TEI><double doi="10.1002/mds.20101"><ISTEX><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Test–retest reliability of UPDRS‐III, dyskinesia scales, and timed motor tests in patients with advanced Parkinson's disease: An argument against multiple baseline assessments</title><author><name sortKey="Metman, Leo Verhagen" sort="Metman, Leo Verhagen" uniqKey="Metman L" first="Leo Verhagen" last="Metman">Leo Verhagen Metman</name></author><author><name sortKey="Myre, Brian" sort="Myre, Brian" uniqKey="Myre B" first="Brian" last="Myre">Brian Myre</name></author><author><name sortKey="Verwey, Niek" sort="Verwey, Niek" uniqKey="Verwey N" first="Niek" last="Verwey">Niek Verwey</name></author><author><name sortKey="Hassin Aer, Sharon" sort="Hassin Aer, Sharon" uniqKey="Hassin Aer S" first="Sharon" last="Hassin-Baer">Sharon Hassin-Baer</name></author><author><name sortKey="Arzbaecher, Jean" sort="Arzbaecher, Jean" uniqKey="Arzbaecher J" first="Jean" last="Arzbaecher">Jean Arzbaecher</name></author><author><name sortKey="Sierens, Diane" sort="Sierens, Diane" uniqKey="Sierens D" first="Diane" last="Sierens">Diane Sierens</name></author><author><name sortKey="Bakay, Roy" sort="Bakay, Roy" uniqKey="Bakay R" first="Roy" last="Bakay">Roy Bakay</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:486DDEEC3D4B55800E3CC8D678506F1F22E5377A</idno><date when="2004" year="2004">2004</date><idno type="doi">10.1002/mds.20101</idno><idno type="url">https://api.istex.fr/document/486DDEEC3D4B55800E3CC8D678506F1F22E5377A/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">001907</idno><idno type="wicri:Area/Istex/Curation">001907</idno><idno type="wicri:Area/Istex/Checkpoint">002491</idno><idno type="wicri:doubleKey">0885-3185:2004:Metman L:test:retest:reliability</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Test–retest reliability of UPDRS‐III, dyskinesia scales, and timed motor tests in patients with advanced Parkinson's disease: An argument against multiple baseline assessments</title><author><name sortKey="Metman, Leo Verhagen" sort="Metman, Leo Verhagen" uniqKey="Metman L" first="Leo Verhagen" last="Metman">Leo Verhagen Metman</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Myre, Brian" sort="Myre, Brian" uniqKey="Myre B" first="Brian" last="Myre">Brian Myre</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Verwey, Niek" sort="Verwey, Niek" uniqKey="Verwey N" first="Niek" last="Verwey">Niek Verwey</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Hassin Aer, Sharon" sort="Hassin Aer, Sharon" uniqKey="Hassin Aer S" first="Sharon" last="Hassin-Baer">Sharon Hassin-Baer</name><affiliation wicri:level="1"><country xml:lang="fr">Israël</country><wicri:regionArea>Department of Neurology, Chaim Sheba Medical Center, Tel‐Hashomer</wicri:regionArea><wicri:noRegion>Tel‐Hashomer</wicri:noRegion></affiliation></author><author><name sortKey="Arzbaecher, Jean" sort="Arzbaecher, Jean" uniqKey="Arzbaecher J" first="Jean" last="Arzbaecher">Jean Arzbaecher</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Chicago Institute of Neurosurgery and Neuroresearch, Chicago, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Sierens, Diane" sort="Sierens, Diane" uniqKey="Sierens D" first="Diane" last="Sierens">Diane Sierens</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Chicago Institute of Neurosurgery and Neuroresearch, Chicago, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Bakay, Roy" sort="Bakay, Roy" uniqKey="Bakay R" first="Roy" last="Bakay">Roy Bakay</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Chicago Institute of Neurosurgery and Neuroresearch, Chicago, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2004-09">2004-09</date><biblScope unit="vol">19</biblScope><biblScope unit="issue">9</biblScope><biblScope unit="page" from="1079">1079</biblScope><biblScope unit="page" to="1084">1084</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">486DDEEC3D4B55800E3CC8D678506F1F22E5377A</idno><idno type="DOI">10.1002/mds.20101</idno><idno type="ArticleID">MDS20101</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>CAPIT</term><term>CAPSIT</term><term>Parkinson's disease</term><term>UPDRS</term><term>test–retest reliability</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The primary objective of this study was to assess the intra‐rater reliability of the motor section of the Unified Parkinson's Disease Rating Scale (UPDRS‐III) in patients with advanced Parkinson's disease (PD). The secondary objective was to assess the intra‐rater reliability of standard timed motor tests and dyskinesia scales to determine the necessity of multiple baseline core evaluations before surgery for PD. We carried out two standardized preoperative core evaluations of patients with advanced PD scheduled to undergo deep brain stimulation. Patients were examined in the defined off and on conditions by the same rater. UPDRS‐III, timed tests, and dyskinesia scores from the two evaluations were compared using Wilcoxon Signed Ranks tests and intraclass correlation coefficients (ICC). Differences in UPDRS‐III scores for the two visits were clinically and statistically nonsignificant, and the ICC was 0.9. Similarly, there were no significant differences in timed motor tests or dyskinesia scores, with a median ICC of 0.8. The results indicate that previous findings of high test–retest reliability of UPDRS‐III in early untreated PD patients can now be extended to those with advanced disease complicated by motor fluctuations. In addition, test–retest reliability of dyskinesia scales and timed motor tests was high. Taken together, these findings challenge the need for multiple baseline assessments as currently stipulated in core assessment protocols for surgical intervention in PD. © 2004 Movement Disorder Society</div></front></TEI></ISTEX><PubMed><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Test-retest reliability of UPDRS-III, dyskinesia scales, and timed motor tests in patients with advanced Parkinson's disease: an argument against multiple baseline assessments.</title><author><name sortKey="Metman, Leo Verhagen" sort="Metman, Leo Verhagen" uniqKey="Metman L" first="Leo Verhagen" last="Metman">Leo Verhagen Metman</name><affiliation wicri:level="2"><nlm:affiliation>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA. lverhage@rush.edu</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Myre, Brian" sort="Myre, Brian" uniqKey="Myre B" first="Brian" last="Myre">Brian Myre</name></author><author><name sortKey="Verwey, Niek" sort="Verwey, Niek" uniqKey="Verwey N" first="Niek" last="Verwey">Niek Verwey</name></author><author><name sortKey="Hassin Baer, Sharon" sort="Hassin Baer, Sharon" uniqKey="Hassin Baer S" first="Sharon" last="Hassin-Baer">Sharon Hassin-Baer</name></author><author><name sortKey="Arzbaecher, Jean" sort="Arzbaecher, Jean" uniqKey="Arzbaecher J" first="Jean" last="Arzbaecher">Jean Arzbaecher</name></author><author><name sortKey="Sierens, Diane" sort="Sierens, Diane" uniqKey="Sierens D" first="Diane" last="Sierens">Diane Sierens</name></author><author><name sortKey="Bakay, Roy" sort="Bakay, Roy" uniqKey="Bakay R" first="Roy" last="Bakay">Roy Bakay</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2004">2004</date><idno type="RBID">pubmed:15372601</idno><idno type="pmid">15372601</idno><idno type="doi">10.1002/mds.20101</idno><idno type="wicri:Area/PubMed/Corpus">003350</idno><idno type="wicri:Area/PubMed/Curation">003350</idno><idno type="wicri:Area/PubMed/Checkpoint">003286</idno><idno type="wicri:Area/Ncbi/Merge">000F38</idno><idno type="wicri:Area/Ncbi/Curation">000F38</idno><idno type="wicri:Area/Ncbi/Checkpoint">000F38</idno><idno type="wicri:doubleKey">0885-3185:2004:Metman L:test:retest:reliability</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Test-retest reliability of UPDRS-III, dyskinesia scales, and timed motor tests in patients with advanced Parkinson's disease: an argument against multiple baseline assessments.</title><author><name sortKey="Metman, Leo Verhagen" sort="Metman, Leo Verhagen" uniqKey="Metman L" first="Leo Verhagen" last="Metman">Leo Verhagen Metman</name><affiliation wicri:level="2"><nlm:affiliation>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA. lverhage@rush.edu</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Myre, Brian" sort="Myre, Brian" uniqKey="Myre B" first="Brian" last="Myre">Brian Myre</name></author><author><name sortKey="Verwey, Niek" sort="Verwey, Niek" uniqKey="Verwey N" first="Niek" last="Verwey">Niek Verwey</name></author><author><name sortKey="Hassin Baer, Sharon" sort="Hassin Baer, Sharon" uniqKey="Hassin Baer S" first="Sharon" last="Hassin-Baer">Sharon Hassin-Baer</name></author><author><name sortKey="Arzbaecher, Jean" sort="Arzbaecher, Jean" uniqKey="Arzbaecher J" first="Jean" last="Arzbaecher">Jean Arzbaecher</name></author><author><name sortKey="Sierens, Diane" sort="Sierens, Diane" uniqKey="Sierens D" first="Diane" last="Sierens">Diane Sierens</name></author><author><name sortKey="Bakay, Roy" sort="Bakay, Roy" uniqKey="Bakay R" first="Roy" last="Bakay">Roy Bakay</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="ISSN">0885-3185</idno><imprint><date when="2004" type="published">2004</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Dyskinesias (diagnosis)</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Parkinson Disease (complications)</term><term>Parkinson Disease (diagnosis)</term><term>Psychomotor Performance</term><term>Questionnaires</term><term>Reproducibility of Results</term><term>Time Factors</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Dyskinesias</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Psychomotor Performance</term><term>Questionnaires</term><term>Reproducibility of Results</term><term>Time Factors</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The primary objective of this study was to assess the intra-rater reliability of the motor section of the Unified Parkinson's Disease Rating Scale (UPDRS-III) in patients with advanced Parkinson's disease (PD). The secondary objective was to assess the intra-rater reliability of standard timed motor tests and dyskinesia scales to determine the necessity of multiple baseline core evaluations before surgery for PD. We carried out two standardized preoperative core evaluations of patients with advanced PD scheduled to undergo deep brain stimulation. Patients were examined in the defined off and on conditions by the same rater. UPDRS-III, timed tests, and dyskinesia scores from the two evaluations were compared using Wilcoxon Signed Ranks tests and intraclass correlation coefficients (ICC). Differences in UPDRS-III scores for the two visits were clinically and statistically nonsignificant, and the ICC was 0.9. Similarly, there were no significant differences in timed motor tests or dyskinesia scores, with a median ICC of 0.8. The results indicate that previous findings of high test-retest reliability of UPDRS-III in early untreated PD patients can now be extended to those with advanced disease complicated by motor fluctuations. In addition, test-retest reliability of dyskinesia scales and timed motor tests was high. Taken together, these findings challenge the need for multiple baseline assessments as currently stipulated in core assessment protocols for surgical intervention in PD.</div></front></TEI></PubMed></double></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 005468 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 005468 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= Main
|étape= Merge
|type= RBID
|clé= ISTEX:486DDEEC3D4B55800E3CC8D678506F1F22E5377A
|texte= Test–retest reliability of UPDRS‐III, dyskinesia scales, and timed motor tests in patients with advanced Parkinson's disease: An argument against multiple baseline assessments
}}
| This area was generated with Dilib version V0.6.23. |  |