Burden of illness in Parkinson's disease
Identifieur interne : 005393 ( Main/Merge ); précédent : 005392; suivant : 005394Burden of illness in Parkinson's disease
Auteurs : Daniel M. Huse [États-Unis] ; Kathy Schulman [États-Unis] ; Lucinda Orsini [États-Unis] ; Jane Castelli-Haley [États-Unis] ; Sean Kennedy [États-Unis] ; Gregory Lenhart [États-Unis]Source :
- Movement disorders [ 0885-3185 ] ; 2005.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
This study quantifies direct medical care costs for individual patients with Parkinson's disease (PD) and projects total national costs of PD. Anonymous, patient-level data on health care utilization and cost were obtained from Medstat's MarketScan Research Databases. Patients were selected for study if they had either two instances of a diagnosis of PD or one diagnosis and two or more prescriptions for PD-related medication. A control group of persons without PD was selected for comparison. Total annual health care utilization and costs were calculated for both PD patients and controls. A total of 20,016 patients with PD were identified and followed up for an average of 853 days. The mean age of the patients was 73.6 years, and 51.2% were women. Total annual direct costs were $23,101 (SD 27,529) per patient with PD versus $11,247 (SD 16,486) for controls. The regression-adjusted incremental direct cost of PD versus control was $10,349 (95% confidence interval, 9,053, 11,645). Adding $25,326 in indirect costs, and multiplying by 645,000 cases of PD in the United States, the total cost to the nation is projected to be $23 billion annually. This estimate is higher than most previous studies, with important implications for health care delivery systems worldwide.
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Pascal:06-0077736Le document en format XML
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Huse</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Thomson Medstat</s1><s2>Cambridge, Massachusetts</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Schulman, Kathy" sort="Schulman, Kathy" uniqKey="Schulman K" first="Kathy" last="Schulman">Kathy Schulman</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Thomson Medstat</s1><s2>Cambridge, Massachusetts</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Orsini, Lucinda" sort="Orsini, Lucinda" uniqKey="Orsini L" first="Lucinda" last="Orsini">Lucinda Orsini</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Thomson Medstat</s1><s2>Cambridge, Massachusetts</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Castelli Haley, Jane" sort="Castelli Haley, Jane" uniqKey="Castelli Haley J" first="Jane" last="Castelli-Haley">Jane Castelli-Haley</name><affiliation wicri:level="2"><inist:fA14 i1="02"><s1>Teva Neuroscience</s1><s2>Kansas City, Missouri</s2><s3>USA</s3><sZ>4 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Missouri (État)</region></placeName></affiliation></author><author><name sortKey="Kennedy, Sean" sort="Kennedy, Sean" uniqKey="Kennedy S" first="Sean" last="Kennedy">Sean Kennedy</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Thomson Medstat</s1><s2>Cambridge, Massachusetts</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Lenhart, Gregory" sort="Lenhart, Gregory" uniqKey="Lenhart G" first="Gregory" last="Lenhart">Gregory Lenhart</name><affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Thomson Medstat</s1><s2>Cambridge, Massachusetts</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Massachusetts</region></placeName></affiliation></author></analytic><series><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno><imprint><date when="2005">2005</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Costs</term><term>Nervous system diseases</term><term>Parkinson disease</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Système nerveux pathologie</term><term>Parkinson maladie</term><term>Coût</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">This study quantifies direct medical care costs for individual patients with Parkinson's disease (PD) and projects total national costs of PD. Anonymous, patient-level data on health care utilization and cost were obtained from Medstat's MarketScan Research Databases. Patients were selected for study if they had either two instances of a diagnosis of PD or one diagnosis and two or more prescriptions for PD-related medication. A control group of persons without PD was selected for comparison. Total annual health care utilization and costs were calculated for both PD patients and controls. A total of 20,016 patients with PD were identified and followed up for an average of 853 days. The mean age of the patients was 73.6 years, and 51.2% were women. Total annual direct costs were $23,101 (SD 27,529) per patient with PD versus $11,247 (SD 16,486) for controls. The regression-adjusted incremental direct cost of PD versus control was $10,349 (95% confidence interval, 9,053, 11,645). Adding $25,326 in indirect costs, and multiplying by 645,000 cases of PD in the United States, the total cost to the nation is projected to be $23 billion annually. This estimate is higher than most previous studies, with important implications for health care delivery systems worldwide.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Massachusetts</li><li>Missouri (État)</li></region></list><tree><country name="États-Unis"><region name="Massachusetts"><name sortKey="Huse, Daniel M" sort="Huse, Daniel M" uniqKey="Huse D" first="Daniel M." last="Huse">Daniel M. Huse</name></region><name sortKey="Castelli Haley, Jane" sort="Castelli Haley, Jane" uniqKey="Castelli Haley J" first="Jane" last="Castelli-Haley">Jane Castelli-Haley</name><name sortKey="Kennedy, Sean" sort="Kennedy, Sean" uniqKey="Kennedy S" first="Sean" last="Kennedy">Sean Kennedy</name><name sortKey="Lenhart, Gregory" sort="Lenhart, Gregory" uniqKey="Lenhart G" first="Gregory" last="Lenhart">Gregory Lenhart</name><name sortKey="Orsini, Lucinda" sort="Orsini, Lucinda" uniqKey="Orsini L" first="Lucinda" last="Orsini">Lucinda Orsini</name><name sortKey="Schulman, Kathy" sort="Schulman, Kathy" uniqKey="Schulman K" first="Kathy" last="Schulman">Kathy Schulman</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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