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Topiramate therapy for paroxysmal kinesigenic choreoathetosis

Identifieur interne : 005164 ( Main/Merge ); précédent : 005163; suivant : 005165

Topiramate therapy for paroxysmal kinesigenic choreoathetosis

Auteurs : Yuan-Gui Huang [République populaire de Chine] ; Yun-Chun Chen [République populaire de Chine] ; FANG DU [République populaire de Chine] ; RUI LI [République populaire de Chine] ; Ge-Lin Xu [République populaire de Chine] ; WEN JIANG [République populaire de Chine] ; JING HUANG [République populaire de Chine]

Source :

Movement disorders [ 0885-3185 ] ; 2005.

RBID : Pascal:05-0173015

Descripteurs français

Pascal (Inist)
- Système nerveux pathologie, Topiramate, Traitement, Choréoathétose, Contrôle moteur.

English descriptors

KwdEn :
- Choreoathetosis, Motor control, Nervous system diseases, Topiramate, Treatment.

Abstract

We observed the clinical efficacy of topiramate for paroxysmal kinesigenic choreoathetosis (PKC). Topiramate was administered as a monotherapy with titrated dosages to 8 patients with PKC. Target daily dose of topiramate was 100 to 200 mg; the follow-up period ranged from 8 months to 2 years. All of the patients became attack-free, and side effects were mild. The results show that topiramate is effective as a monotherapy for treating patients with PKC. The response to topiramate indicates that the disease may be caused by an ion channel defect.

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Pascal:05-0173015

Le document en format XML

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<author><name sortKey="Fang Du" sort="Fang Du" uniqKey="Fang Du" last="Fang Du">FANG DU</name>
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<author><name sortKey="Jing Huang" sort="Jing Huang" uniqKey="Jing Huang" last="Jing Huang">JING HUANG</name>
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<author><name sortKey="Jing Huang" sort="Jing Huang" uniqKey="Jing Huang" last="Jing Huang">JING HUANG</name>
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<series><title level="j" type="main">Movement disorders</title>
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<seriesStmt><title level="j" type="main">Movement disorders</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Choreoathetosis</term>
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<term>Treatment</term>
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<keywords scheme="Pascal" xml:lang="fr"><term>Système nerveux pathologie</term>
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<term>Contrôle moteur</term>
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<front><div type="abstract" xml:lang="en">We observed the clinical efficacy of topiramate for paroxysmal kinesigenic choreoathetosis (PKC). Topiramate was administered as a monotherapy with titrated dosages to 8 patients with PKC. Target daily dose of topiramate was 100 to 200 mg; the follow-up period ranged from 8 months to 2 years. All of the patients became attack-free, and side effects were mild. The results show that topiramate is effective as a monotherapy for treating patients with PKC. The response to topiramate indicates that the disease may be caused by an ion channel defect.</div>
</front>
</TEI>
<affiliations><list><country><li>République populaire de Chine</li>
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<name sortKey="Wen Jiang" sort="Wen Jiang" uniqKey="Wen Jiang" last="Wen Jiang">WEN JIANG</name>
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	Movement Disorders (revue)
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Movement Disorders (revue)

Topiramate therapy for paroxysmal kinesigenic choreoathetosis

Topiramate therapy for paroxysmal kinesigenic choreoathetosis

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri