Essential tremor centralized brain repository: Diagnostic validity and clinical characteristics of a highly selected group of essential tremor cases
Identifieur interne : 005014 ( Main/Merge ); précédent : 005013; suivant : 005015Essential tremor centralized brain repository: Diagnostic validity and clinical characteristics of a highly selected group of essential tremor cases
Auteurs : Elan D. Louis [États-Unis] ; Sarah Borden [États-Unis] ; Carol B. Moskowitz [États-Unis]Source :
- Movement Disorders [ 0885-3185 ] ; 2005-10.
English descriptors
- KwdEn :
- Age of Onset, Aged, Brain (physiopathology), Chin (physiopathology), Diagnosis, Differential, Dystonia (diagnosis), Dystonia (epidemiology), Dystonia (physiopathology), Essential Tremor (diagnosis), Essential Tremor (epidemiology), Essential Tremor (physiopathology), Face (physiopathology), Female, Hearing Aids, Hearing Disorders (epidemiology), Hearing Disorders (therapy), Humans, Male, Neck (physiopathology), Parkinson Disease (diagnosis), Parkinson Disease (epidemiology), Parkinson Disease (physiopathology), Severity of Illness Index, Tongue (physiopathology), Voice Disorders (epidemiology), Voice Disorders (physiopathology), brain bank, clinical characteristics, epidemiology, essential tremor.
- MESH :
- diagnosis : Dystonia, Essential Tremor, Parkinson Disease.
- epidemiology : Dystonia, Essential Tremor, Hearing Disorders, Parkinson Disease, Voice Disorders.
- physiopathology : Brain, Chin, Dystonia, Essential Tremor, Face, Neck, Parkinson Disease, Tongue, Voice Disorders.
- therapy : Hearing Disorders.
- Age of Onset, Aged, Diagnosis, Differential, Female, Hearing Aids, Humans, Male, Severity of Illness Index.
Abstract
We studied essential tremor (ET) cases enrolled in the Essential Tremor Centralized Brain Repository to (1) assess the validity of their diagnoses and (2) characterize the clinical features in a group of highly selected cases who might reflect a far end of the disease spectrum. Our over‐arching goal was to provide a perspective of ET that complements that derived from population‐based and clinic‐based studies. Based on a history and videotaped examination, 94 of 100 ET cases had their diagnoses confirmed; most of the remainder had Parkinson's disease. When compared with ET cases ascertained through populations and clinics, a large proportion had been prescribed medication for tremor (87.2%), had a family history of tremor (88.3%), had rest tremor (33.0%), or had neck tremor (60.6%). One patient had facial tremor, which has not been reported previously. As has been reported once before, a large proportion wore hearing aids (26.9% of the 67 participants age ≥ 70). In summary, diagnostic validity was high. In terms of their clinical characteristics, the high proportion of cases with severe tremor and varied disease manifestations (neck tremor, rest tremor) make these cases a valuable resource in pathological studies; the high proportion with familial tremor would provide an enriched sample for genetic studies. © 2005 Movement Disorder Society
Url:
DOI: 10.1002/mds.20583
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Louis</name><affiliation wicri:level="3"><country>États-Unis</country><placeName><settlement type="city">New York</settlement><region type="state">État de New York</region></placeName><wicri:orgArea>Gertude H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York</wicri:orgArea></affiliation><affiliation wicri:level="3"><country>États-Unis</country><placeName><settlement type="city">New York</settlement><region type="state">État de New York</region></placeName><wicri:orgArea>Department of Neurology, College of Physicians and Surgeons, Columbia University, New York</wicri:orgArea></affiliation><affiliation wicri:level="3"><country>États-Unis</country><placeName><settlement type="city">New York</settlement><region type="state">État de New York</region></placeName><wicri:orgArea>Taub Institute for Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York</wicri:orgArea></affiliation></author><author><name sortKey="Borden, Sarah" sort="Borden, Sarah" uniqKey="Borden S" first="Sarah" last="Borden">Sarah Borden</name><affiliation wicri:level="3"><country>États-Unis</country><placeName><settlement type="city">New York</settlement><region type="state">État de New York</region></placeName><wicri:orgArea>Gertude H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York</wicri:orgArea></affiliation></author><author><name sortKey="Moskowitz, Carol B" sort="Moskowitz, Carol B" uniqKey="Moskowitz C" first="Carol B." last="Moskowitz">Carol B. Moskowitz</name><affiliation wicri:level="3"><country>États-Unis</country><placeName><settlement type="city">New York</settlement><region type="state">État de New York</region></placeName><wicri:orgArea>Department of Neurology, College of Physicians and Surgeons, Columbia University, New York</wicri:orgArea></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2005-10">2005-10</date><biblScope unit="vol">20</biblScope><biblScope unit="issue">10</biblScope><biblScope unit="page" from="1361">1361</biblScope><biblScope unit="page" to="1365">1365</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">BF09DE4B0E2C9C625A2661E13C07FDBB52818629</idno><idno type="DOI">10.1002/mds.20583</idno><idno type="ArticleID">MDS20583</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Age of Onset</term><term>Aged</term><term>Brain (physiopathology)</term><term>Chin (physiopathology)</term><term>Diagnosis, Differential</term><term>Dystonia (diagnosis)</term><term>Dystonia (epidemiology)</term><term>Dystonia (physiopathology)</term><term>Essential Tremor (diagnosis)</term><term>Essential Tremor (epidemiology)</term><term>Essential Tremor (physiopathology)</term><term>Face (physiopathology)</term><term>Female</term><term>Hearing Aids</term><term>Hearing Disorders (epidemiology)</term><term>Hearing Disorders (therapy)</term><term>Humans</term><term>Male</term><term>Neck (physiopathology)</term><term>Parkinson Disease (diagnosis)</term><term>Parkinson Disease (epidemiology)</term><term>Parkinson Disease (physiopathology)</term><term>Severity of Illness Index</term><term>Tongue (physiopathology)</term><term>Voice Disorders (epidemiology)</term><term>Voice Disorders (physiopathology)</term><term>brain bank</term><term>clinical characteristics</term><term>epidemiology</term><term>essential tremor</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Dystonia</term><term>Essential Tremor</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Dystonia</term><term>Essential Tremor</term><term>Hearing Disorders</term><term>Parkinson Disease</term><term>Voice Disorders</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Brain</term><term>Chin</term><term>Dystonia</term><term>Essential Tremor</term><term>Face</term><term>Neck</term><term>Parkinson Disease</term><term>Tongue</term><term>Voice Disorders</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Hearing Disorders</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Age of Onset</term><term>Aged</term><term>Diagnosis, Differential</term><term>Female</term><term>Hearing Aids</term><term>Humans</term><term>Male</term><term>Severity of Illness Index</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="fr">We studied essential tremor (ET) cases enrolled in the Essential Tremor Centralized Brain Repository to (1) assess the validity of their diagnoses and (2) characterize the clinical features in a group of highly selected cases who might reflect a far end of the disease spectrum. Our over‐arching goal was to provide a perspective of ET that complements that derived from population‐based and clinic‐based studies. Based on a history and videotaped examination, 94 of 100 ET cases had their diagnoses confirmed; most of the remainder had Parkinson's disease. When compared with ET cases ascertained through populations and clinics, a large proportion had been prescribed medication for tremor (87.2%), had a family history of tremor (88.3%), had rest tremor (33.0%), or had neck tremor (60.6%). One patient had facial tremor, which has not been reported previously. As has been reported once before, a large proportion wore hearing aids (26.9% of the 67 participants age ≥ 70). In summary, diagnostic validity was high. In terms of their clinical characteristics, the high proportion of cases with severe tremor and varied disease manifestations (neck tremor, rest tremor) make these cases a valuable resource in pathological studies; the high proportion with familial tremor would provide an enriched sample for genetic studies. © 2005 Movement Disorder Society</div></front></TEI><double doi="10.1002/mds.20583"><ISTEX><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Essential tremor centralized brain repository: Diagnostic validity and clinical characteristics of a highly selected group of essential tremor cases</title><author><name sortKey="Louis, Elan D" sort="Louis, Elan D" uniqKey="Louis E" first="Elan D." last="Louis">Elan D. Louis</name></author><author><name sortKey="Borden, Sarah" sort="Borden, Sarah" uniqKey="Borden S" first="Sarah" last="Borden">Sarah Borden</name></author><author><name sortKey="Moskowitz, Carol B" sort="Moskowitz, Carol B" uniqKey="Moskowitz C" first="Carol B." last="Moskowitz">Carol B. Moskowitz</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:BF09DE4B0E2C9C625A2661E13C07FDBB52818629</idno><date when="2005" year="2005">2005</date><idno type="doi">10.1002/mds.20583</idno><idno type="url">https://api.istex.fr/document/BF09DE4B0E2C9C625A2661E13C07FDBB52818629/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">001709</idno><idno type="wicri:Area/Istex/Curation">001709</idno><idno type="wicri:Area/Istex/Checkpoint">002337</idno><idno type="wicri:doubleKey">0885-3185:2005:Louis E:essential:tremor:centralized</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Essential tremor centralized brain repository: Diagnostic validity and clinical characteristics of a highly selected group of essential tremor cases</title><author><name sortKey="Louis, Elan D" sort="Louis, Elan D" uniqKey="Louis E" first="Elan D." last="Louis">Elan D. Louis</name><affiliation wicri:level="3"><country>États-Unis</country><placeName><settlement type="city">New York</settlement><region type="state">État de New York</region></placeName><wicri:orgArea>Gertude H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York</wicri:orgArea></affiliation><affiliation wicri:level="3"><country>États-Unis</country><placeName><settlement type="city">New York</settlement><region type="state">État de New York</region></placeName><wicri:orgArea>Department of Neurology, College of Physicians and Surgeons, Columbia University, New York</wicri:orgArea></affiliation><affiliation wicri:level="3"><country>États-Unis</country><placeName><settlement type="city">New York</settlement><region type="state">État de New York</region></placeName><wicri:orgArea>Taub Institute for Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York</wicri:orgArea></affiliation></author><author><name sortKey="Borden, Sarah" sort="Borden, Sarah" uniqKey="Borden S" first="Sarah" last="Borden">Sarah Borden</name><affiliation wicri:level="3"><country>États-Unis</country><placeName><settlement type="city">New York</settlement><region type="state">État de New York</region></placeName><wicri:orgArea>Gertude H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York</wicri:orgArea></affiliation></author><author><name sortKey="Moskowitz, Carol B" sort="Moskowitz, Carol B" uniqKey="Moskowitz C" first="Carol B." last="Moskowitz">Carol B. Moskowitz</name><affiliation wicri:level="3"><country>États-Unis</country><placeName><settlement type="city">New York</settlement><region type="state">État de New York</region></placeName><wicri:orgArea>Department of Neurology, College of Physicians and Surgeons, Columbia University, New York</wicri:orgArea></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2005-10">2005-10</date><biblScope unit="vol">20</biblScope><biblScope unit="issue">10</biblScope><biblScope unit="page" from="1361">1361</biblScope><biblScope unit="page" to="1365">1365</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">BF09DE4B0E2C9C625A2661E13C07FDBB52818629</idno><idno type="DOI">10.1002/mds.20583</idno><idno type="ArticleID">MDS20583</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>brain bank</term><term>clinical characteristics</term><term>epidemiology</term><term>essential tremor</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="fr">We studied essential tremor (ET) cases enrolled in the Essential Tremor Centralized Brain Repository to (1) assess the validity of their diagnoses and (2) characterize the clinical features in a group of highly selected cases who might reflect a far end of the disease spectrum. Our over‐arching goal was to provide a perspective of ET that complements that derived from population‐based and clinic‐based studies. Based on a history and videotaped examination, 94 of 100 ET cases had their diagnoses confirmed; most of the remainder had Parkinson's disease. When compared with ET cases ascertained through populations and clinics, a large proportion had been prescribed medication for tremor (87.2%), had a family history of tremor (88.3%), had rest tremor (33.0%), or had neck tremor (60.6%). One patient had facial tremor, which has not been reported previously. As has been reported once before, a large proportion wore hearing aids (26.9% of the 67 participants age ≥ 70). In summary, diagnostic validity was high. In terms of their clinical characteristics, the high proportion of cases with severe tremor and varied disease manifestations (neck tremor, rest tremor) make these cases a valuable resource in pathological studies; the high proportion with familial tremor would provide an enriched sample for genetic studies. © 2005 Movement Disorder Society</div></front></TEI></ISTEX><PubMed><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Essential tremor centralized brain repository: diagnostic validity and clinical characteristics of a highly selected group of essential tremor cases.</title><author><name sortKey="Louis, Elan D" sort="Louis, Elan D" uniqKey="Louis E" first="Elan D" last="Louis">Elan D. Louis</name><affiliation wicri:level="4"><nlm:affiliation>Gertude H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA. EDL2@columbia.edu</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Gertude H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, New York 10032</wicri:regionArea><orgName type="university">Université Columbia</orgName><placeName><settlement type="city">New York</settlement><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Borden, Sarah" sort="Borden, Sarah" uniqKey="Borden S" first="Sarah" last="Borden">Sarah Borden</name></author><author><name sortKey="Moskowitz, Carol B" sort="Moskowitz, Carol B" uniqKey="Moskowitz C" first="Carol B" last="Moskowitz">Carol B. Moskowitz</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2005">2005</date><idno type="doi">10.1002/mds.20583</idno><idno type="RBID">pubmed:16001407</idno><idno type="pmid">16001407</idno><idno type="wicri:Area/PubMed/Corpus">003007</idno><idno type="wicri:Area/PubMed/Curation">003007</idno><idno type="wicri:Area/PubMed/Checkpoint">003141</idno><idno type="wicri:Area/Ncbi/Merge">001305</idno><idno type="wicri:Area/Ncbi/Curation">001305</idno><idno type="wicri:Area/Ncbi/Checkpoint">001305</idno><idno type="wicri:doubleKey">0885-3185:2005:Louis E:essential:tremor:centralized</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Essential tremor centralized brain repository: diagnostic validity and clinical characteristics of a highly selected group of essential tremor cases.</title><author><name sortKey="Louis, Elan D" sort="Louis, Elan D" uniqKey="Louis E" first="Elan D" last="Louis">Elan D. Louis</name><affiliation wicri:level="4"><nlm:affiliation>Gertude H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA. EDL2@columbia.edu</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Gertude H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, New York 10032</wicri:regionArea><orgName type="university">Université Columbia</orgName><placeName><settlement type="city">New York</settlement><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Borden, Sarah" sort="Borden, Sarah" uniqKey="Borden S" first="Sarah" last="Borden">Sarah Borden</name></author><author><name sortKey="Moskowitz, Carol B" sort="Moskowitz, Carol B" uniqKey="Moskowitz C" first="Carol B" last="Moskowitz">Carol B. Moskowitz</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="ISSN">0885-3185</idno><imprint><date when="2005" type="published">2005</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Age of Onset</term><term>Aged</term><term>Brain (physiopathology)</term><term>Chin (physiopathology)</term><term>Diagnosis, Differential</term><term>Dystonia (diagnosis)</term><term>Dystonia (epidemiology)</term><term>Dystonia (physiopathology)</term><term>Essential Tremor (diagnosis)</term><term>Essential Tremor (epidemiology)</term><term>Essential Tremor (physiopathology)</term><term>Face (physiopathology)</term><term>Female</term><term>Hearing Aids</term><term>Hearing Disorders (epidemiology)</term><term>Hearing Disorders (therapy)</term><term>Humans</term><term>Male</term><term>Neck (physiopathology)</term><term>Parkinson Disease (diagnosis)</term><term>Parkinson Disease (epidemiology)</term><term>Parkinson Disease (physiopathology)</term><term>Severity of Illness Index</term><term>Tongue (physiopathology)</term><term>Voice Disorders (epidemiology)</term><term>Voice Disorders (physiopathology)</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Dystonia</term><term>Essential Tremor</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Dystonia</term><term>Essential Tremor</term><term>Hearing Disorders</term><term>Parkinson Disease</term><term>Voice Disorders</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Brain</term><term>Chin</term><term>Dystonia</term><term>Essential Tremor</term><term>Face</term><term>Neck</term><term>Parkinson Disease</term><term>Tongue</term><term>Voice Disorders</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Hearing Disorders</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Age of Onset</term><term>Aged</term><term>Diagnosis, Differential</term><term>Female</term><term>Hearing Aids</term><term>Humans</term><term>Male</term><term>Severity of Illness Index</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We studied essential tremor (ET) cases enrolled in the Essential Tremor Centralized Brain Repository to (1) assess the validity of their diagnoses and (2) characterize the clinical features in a group of highly selected cases who might reflect a far end of the disease spectrum. Our over-arching goal was to provide a perspective of ET that complements that derived from population-based and clinic-based studies. Based on a history and videotaped examination, 94 of 100 ET cases had their diagnoses confirmed; most of the remainder had Parkinson's disease. When compared with ET cases ascertained through populations and clinics, a large proportion had been prescribed medication for tremor (87.2%), had a family history of tremor (88.3%), had rest tremor (33.0%), or had neck tremor (60.6%). One patient had facial tremor, which has not been reported previously. As has been reported once before, a large proportion wore hearing aids (26.9% of the 67 participants age>or=70). In summary, diagnostic validity was high. In terms of their clinical characteristics, the high proportion of cases with severe tremor and varied disease manifestations (neck tremor, rest tremor) make these cases a valuable resource in pathological studies; the high proportion with familial tremor would provide an enriched sample for genetic studies.</div></front></TEI></PubMed></double></record>Pour manipuler ce document sous Unix (Dilib)
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