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Levodopa-induced sleepiness in the parkinson variant of multiple system atrophy

Identifieur interne : 004B26 ( Main/Merge ); précédent : 004B25; suivant : 004B27

Levodopa-induced sleepiness in the parkinson variant of multiple system atrophy

Auteurs : Klaus Seppi [Autriche] ; Birgit Högl [Autriche] ; Anja Diem [Autriche] ; Cecilia Peralta [Autriche] ; Gregor K. Wenning [Autriche] ; Werner Poewe [Autriche]

Source :

Movement disorders [ 0885-3185 ] ; 2006.

RBID : Pascal:06-0435117

Descripteurs français

Pascal (Inist)
- Système nerveux pathologie, Atrophie multisystématisée, Parkinson maladie, Lévodopa, Echelle d'évaluation.

English descriptors

KwdEn :
- Evaluation scale, Levodopa, Multiple system atrophy, Nervous system diseases, Parkinson disease.

Abstract

Recent observations suggest that levodopa can induce irresistible sleep onset in multiple system atrophy (MSA). Therefore, we assessed sleepiness during a levodopa challenge in 17 MSA compared with 23 Parkinson's disease (PD) patients using the Stanford Sleepiness Scale (SSS). SSS scores during the levodopa challenge compared with baseline were significantly increased in the MSA compared with the PD group. These findings suggest greater potential of levodopa to induce sleepiness in MSA compared with PD, which may be related to differences in basal ganglia and brainstem pathology between the two disorders.

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Pascal:06-0435117

Le document en format XML

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<front><div type="abstract" xml:lang="en">Recent observations suggest that levodopa can induce irresistible sleep onset in multiple system atrophy (MSA). Therefore, we assessed sleepiness during a levodopa challenge in 17 MSA compared with 23 Parkinson's disease (PD) patients using the Stanford Sleepiness Scale (SSS). SSS scores during the levodopa challenge compared with baseline were significantly increased in the MSA compared with the PD group. These findings suggest greater potential of levodopa to induce sleepiness in MSA compared with PD, which may be related to differences in basal ganglia and brainstem pathology between the two disorders.</div>
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	Movement Disorders (revue)
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Movement Disorders (revue)

Levodopa-induced sleepiness in the parkinson variant of multiple system atrophy

Levodopa-induced sleepiness in the parkinson variant of multiple system atrophy

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri