Clinical diagnostic criteria for dementia associated with parkinson's disease
Identifieur interne : 004333 ( Main/Merge ); précédent : 004332; suivant : 004334Clinical diagnostic criteria for dementia associated with parkinson's disease
Auteurs : Murat Emre [Turquie] ; Dag Aarsland [Norvège] ; Richard Brown [Royaume-Uni] ; David J. Burn [Royaume-Uni] ; Charles Duyckaerts [France] ; Yoshikino Mizuno [Japon] ; Gerald Anthony Broe [Australie] ; Jeffrey Cummings [États-Unis] ; Dennis W. Dickson [États-Unis] ; Serge Gauthier [Canada] ; Jennifer Goldman [États-Unis] ; Christopher Goetz [États-Unis] ; Amos Korczyn [Israël] ; Andrew Lees (neurologue) [Royaume-Uni] ; Richard Levy [France] ; Irene Litvan [États-Unis] ; Ian Mckeith [Royaume-Uni] ; Warren Olanow [États-Unis] ; Werner Poewe [Autriche] ; Niall Quinn [Royaume-Uni] ; Christina Sampaio [Portugal] ; Eduardo Tolosa [Espagne] ; Bruno Dubois [France]Source :
- Movement disorders [ 0885-3185 ] ; 2007.
Descripteurs français
- Pascal (Inist)
English descriptors
Abstract
Dementia has been increasingly more recognized to be a common feature in patients with Parkinson's disease (PD), especially in old age. Specific criteria for the clinical diagnosis of dementia associated with PD (PD-D), however, have been lacking. A Task Force, organized by the Movement Disorder Study, was charged with the development of clinical diagnostic criteria for PD-D. The Task Force members were assigned to sub-committees and performed a systematic review of the literature, based on pre-defined selection criteria, in order to identify the epidemiological, clinical, auxiliary, and pathological features of PD-D. Clinical diagnostic criteria were then developed based on these findings and group consensus. The incidence of dementia in PD is increased up to six times, point-prevelance is close to 30%, older age and akinetic-rigid form are associated with higher risk. PD-D is characterized by impairment in attention, memory, executive and visuo-spatial functions, behavioral symptoms such as affective changes, hallucinations, and apathy are frequent. There are no specific ancillary investigations for the diagnosis; the main pathological correlate is Lewy body-type degeneration in cerebral cortex and limbic structures. Based on the characteristic features associated with this condition, clinical diagnostic criteria for probable and possible PD-D are proposed.
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Clinical diagnostic criteria for dementia associated with parkinson's disease</title><author><name sortKey="Emre, Murat" sort="Emre, Murat" uniqKey="Emre M" first="Murat" last="Emre">Murat Emre</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Behavioral Neurology and Movement Disorders Unit, Istanbul Faculty of Medicine, Istanbul University</s1><s2>Istanbul</s2><s3>TUR</s3><sZ>1 aut.</sZ></inist:fA14><country>Turquie</country><wicri:noRegion>Istanbul</wicri:noRegion></affiliation></author><author><name sortKey="Aarsland, Dag" sort="Aarsland, Dag" uniqKey="Aarsland D" first="Dag" last="Aarsland">Dag Aarsland</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Norwegian Centre for Movement Disorders, Stavanger University Hospital</s1><s2>Stavanger</s2><s3>NOR</s3><sZ>2 aut.</sZ></inist:fA14><country>Norvège</country><wicri:noRegion>Stavanger</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>School of Medicine, University of Bergen</s1><s3>NOR</s3><sZ>2 aut.</sZ></inist:fA14><country>Norvège</country><wicri:noRegion>School of Medicine, University of Bergen</wicri:noRegion></affiliation></author><author><name sortKey="Brown, Richard" sort="Brown, Richard" uniqKey="Brown R" first="Richard" last="Brown">Richard Brown</name><affiliation wicri:level="3"><inist:fA14 i1="04"><s1>King's College, MRC Centre for Neurodegeneration Research, Institute of Psychiatry</s1><s2>London</s2><s3>GBR</s3><sZ>3 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Burn, David J" sort="Burn, David J" uniqKey="Burn D" first="David J." last="Burn">David J. Burn</name><affiliation wicri:level="1"><inist:fA14 i1="05"><s1>Institute for Ageing and Health, Newcastle University, Wolfson Research Centre</s1><s2>Newcastle upon Tyne</s2><s3>GBR</s3><sZ>4 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Newcastle upon Tyne</wicri:noRegion></affiliation></author><author><name sortKey="Duyckaerts, Charles" sort="Duyckaerts, Charles" uniqKey="Duyckaerts C" first="Charles" last="Duyckaerts">Charles Duyckaerts</name><affiliation wicri:level="1"><inist:fA14 i1="06"><s1>Neuropathology Laboratory, La Salpetriere Hospital, Paris VI Pierre et Marie Curie University, Inserm U679</s1><s2>Paris</s2><s3>FRA</s3><sZ>5 aut.</sZ></inist:fA14><country>France</country><placeName><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Mizuno, Yoshikino" sort="Mizuno, Yoshikino" uniqKey="Mizuno Y" first="Yoshikino" last="Mizuno">Yoshikino Mizuno</name><affiliation wicri:level="3"><inist:fA14 i1="07"><s1>Department of Neurology, Juntendo University School of Medicine</s1><s2>Bunkyo-ku, Tokyo</s2><s3>JPN</s3><sZ>6 aut.</sZ></inist:fA14><country>Japon</country><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="08"><s1>Research Institute for Diseases of Old Ages, Juntendo University School of Medicine</s1><s2>Bunkyo-ku, Tokyo</s2><s3>JPN</s3><sZ>6 aut.</sZ></inist:fA14><country>Japon</country><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation></author><author><name sortKey="Broe, Gerald Anthony" sort="Broe, Gerald Anthony" uniqKey="Broe G" first="Gerald Anthony" last="Broe">Gerald Anthony Broe</name><affiliation wicri:level="1"><inist:fA14 i1="09"><s1>Ageing Research Centre, Prince of Wales Hospital</s1><s2>Randwick, New South Wales</s2><s3>AUS</s3><sZ>7 aut.</sZ></inist:fA14><country>Australie</country><wicri:noRegion>Randwick, New South Wales</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="10"><s1>Faculty of Medicine, Prince of Wales Medical Research Institute, University of New South Wales</s1><s2>Randwick, New South Wales</s2><s3>AUS</s3><sZ>7 aut.</sZ></inist:fA14><country>Australie</country><wicri:noRegion>Randwick, New South Wales</wicri:noRegion></affiliation></author><author><name sortKey="Cummings, Jeffrey" sort="Cummings, Jeffrey" uniqKey="Cummings J" first="Jeffrey" last="Cummings">Jeffrey Cummings</name><affiliation wicri:level="2"><inist:fA14 i1="11"><s1>Department of Neurology, David Geffen School of Medicine at UCLA</s1><s2>Los Angeles, California</s2><s3>USA</s3><sZ>8 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Dickson, Dennis W" sort="Dickson, Dennis W" uniqKey="Dickson D" first="Dennis W." last="Dickson">Dennis W. Dickson</name><affiliation wicri:level="2"><inist:fA14 i1="12"><s1>Department of Neuroscience, Mayo Clinic College of Medicine</s1><s2>Jacksonville, Florida</s2><s3>USA</s3><sZ>9 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Gauthier, Serge" sort="Gauthier, Serge" uniqKey="Gauthier S" first="Serge" last="Gauthier">Serge Gauthier</name><affiliation wicri:level="1"><inist:fA14 i1="13"><s1>Alzheimer Disease and Related Disorders Unit, McGill Center for Studies in Aging</s1><s2>Montreal, Quebec</s2><s3>CAN</s3><sZ>10 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Montreal, Quebec</wicri:noRegion></affiliation></author><author><name sortKey="Goldman, Jennifer" sort="Goldman, Jennifer" uniqKey="Goldman J" first="Jennifer" last="Goldman">Jennifer Goldman</name><affiliation wicri:level="2"><inist:fA14 i1="14"><s1>Department of Neurological Sciences, Rush University Medical Center</s1><s2>Chicago, Illinois</s2><s3>USA</s3><sZ>11 aut.</sZ><sZ>12 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Goetz, Christopher" sort="Goetz, Christopher" uniqKey="Goetz C" first="Christopher" last="Goetz">Christopher Goetz</name><affiliation wicri:level="2"><inist:fA14 i1="14"><s1>Department of Neurological Sciences, Rush University Medical Center</s1><s2>Chicago, Illinois</s2><s3>USA</s3><sZ>11 aut.</sZ><sZ>12 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Korczyn, Amos" sort="Korczyn, Amos" uniqKey="Korczyn A" first="Amos" last="Korczyn">Amos Korczyn</name><affiliation wicri:level="1"><inist:fA14 i1="15"><s1>Department of Neurology, Tel-Aviv University</s1><s2>Ramat -Aviv</s2><s3>ISR</s3><sZ>13 aut.</sZ></inist:fA14><country>Israël</country><wicri:noRegion>Ramat -Aviv</wicri:noRegion></affiliation></author><author><name sortKey="Lees, Andrew" sort="Lees, Andrew" uniqKey="Lees A" first="Andrew" last="Lees">Andrew Lees (neurologue)</name><affiliation wicri:level="3"><inist:fA14 i1="16"><s1>Department of Neurology, The National Hospital for Neurology and Neurosurgery, Queen Square</s1><s2>London</s2><s3>GBR</s3><sZ>14 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName><orgName>National Hospital for Neurology and Neurosurgery</orgName></affiliation></author><author><name sortKey="Levy, Richard" sort="Levy, Richard" uniqKey="Levy R" first="Richard" last="Levy">Richard Levy</name><affiliation wicri:level="1"><inist:fA14 i1="17"><s1>Federation de Neurologic, INSERM U.610, AP-HP, Groupe Hospitalier Pitié-Salpetriere</s1><s2>Paris</s2><s3>FRA</s3><sZ>15 aut.</sZ></inist:fA14><country>France</country><placeName><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Litvan, Irene" sort="Litvan, Irene" uniqKey="Litvan I" first="Irene" last="Litvan">Irene Litvan</name><affiliation wicri:level="2"><inist:fA14 i1="18"><s1>Movement Disorder Program, Department of Neurology, University of Louisville School of Medicine</s1><s2>Louisville, Kentucky</s2><s3>USA</s3><sZ>16 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Kentucky</region></placeName></affiliation></author><author><name sortKey="Mckeith, Ian" sort="Mckeith, Ian" uniqKey="Mckeith I" first="Ian" last="Mckeith">Ian Mckeith</name><affiliation wicri:level="1"><inist:fA14 i1="19"><s1>Wolfson Research Centre, Newcastle General Hospital</s1><s2>Newcastle upon Tyne</s2><s3>GBR</s3><sZ>17 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Newcastle upon Tyne</wicri:noRegion></affiliation></author><author><name sortKey="Olanow, Warren" sort="Olanow, Warren" uniqKey="Olanow W" first="Warren" last="Olanow">Warren Olanow</name><affiliation wicri:level="2"><inist:fA14 i1="20"><s1>Department of Neurology and Department of Neuroscience, Mount Sinai School of Medicine</s1><s2>New York</s2><s3>USA</s3><sZ>18 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Poewe, Werner" sort="Poewe, Werner" uniqKey="Poewe W" first="Werner" last="Poewe">Werner Poewe</name><affiliation wicri:level="4"><inist:fA14 i1="21"><s1>Department of Neurology, Medical University of Innsbruck</s1><s2>Innsbruck</s2><s3>AUT</s3><sZ>19 aut.</sZ></inist:fA14><country>Autriche</country><placeName><settlement type="city">Innsbruck</settlement><region nuts="2" type="region">Tyrol (Land)</region></placeName><orgName type="university">Université de médecine d'Innsbruck</orgName><placeName><settlement type="city">Innsbruck</settlement><region nuts="2" type="region">Tyrol (Land)</region></placeName><orgName type="university">Université de médecine d'Innsbruck</orgName></affiliation></author><author><name sortKey="Quinn, Niall" sort="Quinn, Niall" uniqKey="Quinn N" first="Niall" last="Quinn">Niall Quinn</name><affiliation wicri:level="3"><inist:fA14 i1="22"><s1>Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, Queen Square</s1><s2>London</s2><s3>GBR</s3><sZ>20 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Sampaio, Christina" sort="Sampaio, Christina" uniqKey="Sampaio C" first="Christina" last="Sampaio">Christina Sampaio</name><affiliation wicri:level="1"><inist:fA14 i1="23"><s1>Laboratorio de Farmacologia Clinica e Terapeutica, Faculdade de Medicina de Lisboa e Institute de Medicina Molecular</s1><s2>Lisboa</s2><s3>PRT</s3><sZ>21 aut.</sZ></inist:fA14><country>Portugal</country><wicri:noRegion>Lisboa</wicri:noRegion></affiliation></author><author><name sortKey="Tolosa, Eduardo" sort="Tolosa, Eduardo" uniqKey="Tolosa E" first="Eduardo" last="Tolosa">Eduardo Tolosa</name><affiliation wicri:level="1"><inist:fA14 i1="24"><s1>Parkinson's Disease and Movement Disorders Unit, Neurology Service, Institut Clinic de Neurociences, Hospital Clinic de Barcelona, IDIBAPS, Universitat de Barcelona</s1><s3>ESP</s3><sZ>22 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>Parkinson's Disease and Movement Disorders Unit, Neurology Service, Institut Clinic de Neurociences, Hospital Clinic de Barcelona, IDIBAPS, Universitat de Barcelona</wicri:noRegion></affiliation></author><author><name sortKey="Dubois, Bruno" sort="Dubois, Bruno" uniqKey="Dubois B" first="Bruno" last="Dubois">Bruno Dubois</name><affiliation wicri:level="1"><inist:fA14 i1="25"><s1>INSERM U610, Pavilion Claude Bernard, Hopital de la Salpetriere</s1><s2>Paris</s2><s3>FRA</s3><sZ>23 aut.</sZ></inist:fA14><country>France</country><placeName><settlement type="city">Paris</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">07-0491115</idno><date when="2007">2007</date><idno type="stanalyst">PASCAL 07-0491115 INIST</idno><idno type="RBID">Pascal:07-0491115</idno><idno type="wicri:Area/PascalFrancis/Corpus">001547</idno><idno type="wicri:Area/PascalFrancis/Curation">001774</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">001743</idno><idno type="wicri:doubleKey">0885-3185:2007:Emre M:clinical:diagnostic:criteria</idno><idno type="wicri:Area/Main/Merge">004333</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Clinical diagnostic criteria for dementia associated with parkinson's disease</title><author><name sortKey="Emre, Murat" sort="Emre, Murat" uniqKey="Emre M" first="Murat" last="Emre">Murat Emre</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Behavioral Neurology and Movement Disorders Unit, Istanbul Faculty of Medicine, Istanbul University</s1><s2>Istanbul</s2><s3>TUR</s3><sZ>1 aut.</sZ></inist:fA14><country>Turquie</country><wicri:noRegion>Istanbul</wicri:noRegion></affiliation></author><author><name sortKey="Aarsland, Dag" sort="Aarsland, Dag" uniqKey="Aarsland D" first="Dag" last="Aarsland">Dag Aarsland</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Norwegian Centre for Movement Disorders, Stavanger University Hospital</s1><s2>Stavanger</s2><s3>NOR</s3><sZ>2 aut.</sZ></inist:fA14><country>Norvège</country><wicri:noRegion>Stavanger</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>School of Medicine, University of Bergen</s1><s3>NOR</s3><sZ>2 aut.</sZ></inist:fA14><country>Norvège</country><wicri:noRegion>School of Medicine, University of Bergen</wicri:noRegion></affiliation></author><author><name sortKey="Brown, Richard" sort="Brown, Richard" uniqKey="Brown R" first="Richard" last="Brown">Richard Brown</name><affiliation wicri:level="3"><inist:fA14 i1="04"><s1>King's College, MRC Centre for Neurodegeneration Research, Institute of Psychiatry</s1><s2>London</s2><s3>GBR</s3><sZ>3 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Burn, David J" sort="Burn, David J" uniqKey="Burn D" first="David J." last="Burn">David J. Burn</name><affiliation wicri:level="1"><inist:fA14 i1="05"><s1>Institute for Ageing and Health, Newcastle University, Wolfson Research Centre</s1><s2>Newcastle upon Tyne</s2><s3>GBR</s3><sZ>4 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Newcastle upon Tyne</wicri:noRegion></affiliation></author><author><name sortKey="Duyckaerts, Charles" sort="Duyckaerts, Charles" uniqKey="Duyckaerts C" first="Charles" last="Duyckaerts">Charles Duyckaerts</name><affiliation wicri:level="1"><inist:fA14 i1="06"><s1>Neuropathology Laboratory, La Salpetriere Hospital, Paris VI Pierre et Marie Curie University, Inserm U679</s1><s2>Paris</s2><s3>FRA</s3><sZ>5 aut.</sZ></inist:fA14><country>France</country><placeName><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Mizuno, Yoshikino" sort="Mizuno, Yoshikino" uniqKey="Mizuno Y" first="Yoshikino" last="Mizuno">Yoshikino Mizuno</name><affiliation wicri:level="3"><inist:fA14 i1="07"><s1>Department of Neurology, Juntendo University School of Medicine</s1><s2>Bunkyo-ku, Tokyo</s2><s3>JPN</s3><sZ>6 aut.</sZ></inist:fA14><country>Japon</country><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="08"><s1>Research Institute for Diseases of Old Ages, Juntendo University School of Medicine</s1><s2>Bunkyo-ku, Tokyo</s2><s3>JPN</s3><sZ>6 aut.</sZ></inist:fA14><country>Japon</country><placeName><settlement type="city">Tokyo</settlement></placeName></affiliation></author><author><name sortKey="Broe, Gerald Anthony" sort="Broe, Gerald Anthony" uniqKey="Broe G" first="Gerald Anthony" last="Broe">Gerald Anthony Broe</name><affiliation wicri:level="1"><inist:fA14 i1="09"><s1>Ageing Research Centre, Prince of Wales Hospital</s1><s2>Randwick, New South Wales</s2><s3>AUS</s3><sZ>7 aut.</sZ></inist:fA14><country>Australie</country><wicri:noRegion>Randwick, New South Wales</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="10"><s1>Faculty of Medicine, Prince of Wales Medical Research Institute, University of New South Wales</s1><s2>Randwick, New South Wales</s2><s3>AUS</s3><sZ>7 aut.</sZ></inist:fA14><country>Australie</country><wicri:noRegion>Randwick, New South Wales</wicri:noRegion></affiliation></author><author><name sortKey="Cummings, Jeffrey" sort="Cummings, Jeffrey" uniqKey="Cummings J" first="Jeffrey" last="Cummings">Jeffrey Cummings</name><affiliation wicri:level="2"><inist:fA14 i1="11"><s1>Department of Neurology, David Geffen School of Medicine at UCLA</s1><s2>Los Angeles, California</s2><s3>USA</s3><sZ>8 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Dickson, Dennis W" sort="Dickson, Dennis W" uniqKey="Dickson D" first="Dennis W." last="Dickson">Dennis W. Dickson</name><affiliation wicri:level="2"><inist:fA14 i1="12"><s1>Department of Neuroscience, Mayo Clinic College of Medicine</s1><s2>Jacksonville, Florida</s2><s3>USA</s3><sZ>9 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Gauthier, Serge" sort="Gauthier, Serge" uniqKey="Gauthier S" first="Serge" last="Gauthier">Serge Gauthier</name><affiliation wicri:level="1"><inist:fA14 i1="13"><s1>Alzheimer Disease and Related Disorders Unit, McGill Center for Studies in Aging</s1><s2>Montreal, Quebec</s2><s3>CAN</s3><sZ>10 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Montreal, Quebec</wicri:noRegion></affiliation></author><author><name sortKey="Goldman, Jennifer" sort="Goldman, Jennifer" uniqKey="Goldman J" first="Jennifer" last="Goldman">Jennifer Goldman</name><affiliation wicri:level="2"><inist:fA14 i1="14"><s1>Department of Neurological Sciences, Rush University Medical Center</s1><s2>Chicago, Illinois</s2><s3>USA</s3><sZ>11 aut.</sZ><sZ>12 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Goetz, Christopher" sort="Goetz, Christopher" uniqKey="Goetz C" first="Christopher" last="Goetz">Christopher Goetz</name><affiliation wicri:level="2"><inist:fA14 i1="14"><s1>Department of Neurological Sciences, Rush University Medical Center</s1><s2>Chicago, Illinois</s2><s3>USA</s3><sZ>11 aut.</sZ><sZ>12 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Korczyn, Amos" sort="Korczyn, Amos" uniqKey="Korczyn A" first="Amos" last="Korczyn">Amos Korczyn</name><affiliation wicri:level="1"><inist:fA14 i1="15"><s1>Department of Neurology, Tel-Aviv University</s1><s2>Ramat -Aviv</s2><s3>ISR</s3><sZ>13 aut.</sZ></inist:fA14><country>Israël</country><wicri:noRegion>Ramat -Aviv</wicri:noRegion></affiliation></author><author><name sortKey="Lees, Andrew" sort="Lees, Andrew" uniqKey="Lees A" first="Andrew" last="Lees">Andrew Lees (neurologue)</name><affiliation wicri:level="3"><inist:fA14 i1="16"><s1>Department of Neurology, The National Hospital for Neurology and Neurosurgery, Queen Square</s1><s2>London</s2><s3>GBR</s3><sZ>14 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName><orgName>National Hospital for Neurology and Neurosurgery</orgName></affiliation></author><author><name sortKey="Levy, Richard" sort="Levy, Richard" uniqKey="Levy R" first="Richard" last="Levy">Richard Levy</name><affiliation wicri:level="1"><inist:fA14 i1="17"><s1>Federation de Neurologic, INSERM U.610, AP-HP, Groupe Hospitalier Pitié-Salpetriere</s1><s2>Paris</s2><s3>FRA</s3><sZ>15 aut.</sZ></inist:fA14><country>France</country><placeName><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Litvan, Irene" sort="Litvan, Irene" uniqKey="Litvan I" first="Irene" last="Litvan">Irene Litvan</name><affiliation wicri:level="2"><inist:fA14 i1="18"><s1>Movement Disorder Program, Department of Neurology, University of Louisville School of Medicine</s1><s2>Louisville, Kentucky</s2><s3>USA</s3><sZ>16 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">Kentucky</region></placeName></affiliation></author><author><name sortKey="Mckeith, Ian" sort="Mckeith, Ian" uniqKey="Mckeith I" first="Ian" last="Mckeith">Ian Mckeith</name><affiliation wicri:level="1"><inist:fA14 i1="19"><s1>Wolfson Research Centre, Newcastle General Hospital</s1><s2>Newcastle upon Tyne</s2><s3>GBR</s3><sZ>17 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Newcastle upon Tyne</wicri:noRegion></affiliation></author><author><name sortKey="Olanow, Warren" sort="Olanow, Warren" uniqKey="Olanow W" first="Warren" last="Olanow">Warren Olanow</name><affiliation wicri:level="2"><inist:fA14 i1="20"><s1>Department of Neurology and Department of Neuroscience, Mount Sinai School of Medicine</s1><s2>New York</s2><s3>USA</s3><sZ>18 aut.</sZ></inist:fA14><country>États-Unis</country><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Poewe, Werner" sort="Poewe, Werner" uniqKey="Poewe W" first="Werner" last="Poewe">Werner Poewe</name><affiliation wicri:level="4"><inist:fA14 i1="21"><s1>Department of Neurology, Medical University of Innsbruck</s1><s2>Innsbruck</s2><s3>AUT</s3><sZ>19 aut.</sZ></inist:fA14><country>Autriche</country><placeName><settlement type="city">Innsbruck</settlement><region nuts="2" type="region">Tyrol (Land)</region></placeName><orgName type="university">Université de médecine d'Innsbruck</orgName><placeName><settlement type="city">Innsbruck</settlement><region nuts="2" type="region">Tyrol (Land)</region></placeName><orgName type="university">Université de médecine d'Innsbruck</orgName></affiliation></author><author><name sortKey="Quinn, Niall" sort="Quinn, Niall" uniqKey="Quinn N" first="Niall" last="Quinn">Niall Quinn</name><affiliation wicri:level="3"><inist:fA14 i1="22"><s1>Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, Queen Square</s1><s2>London</s2><s3>GBR</s3><sZ>20 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Sampaio, Christina" sort="Sampaio, Christina" uniqKey="Sampaio C" first="Christina" last="Sampaio">Christina Sampaio</name><affiliation wicri:level="1"><inist:fA14 i1="23"><s1>Laboratorio de Farmacologia Clinica e Terapeutica, Faculdade de Medicina de Lisboa e Institute de Medicina Molecular</s1><s2>Lisboa</s2><s3>PRT</s3><sZ>21 aut.</sZ></inist:fA14><country>Portugal</country><wicri:noRegion>Lisboa</wicri:noRegion></affiliation></author><author><name sortKey="Tolosa, Eduardo" sort="Tolosa, Eduardo" uniqKey="Tolosa E" first="Eduardo" last="Tolosa">Eduardo Tolosa</name><affiliation wicri:level="1"><inist:fA14 i1="24"><s1>Parkinson's Disease and Movement Disorders Unit, Neurology Service, Institut Clinic de Neurociences, Hospital Clinic de Barcelona, IDIBAPS, Universitat de Barcelona</s1><s3>ESP</s3><sZ>22 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>Parkinson's Disease and Movement Disorders Unit, Neurology Service, Institut Clinic de Neurociences, Hospital Clinic de Barcelona, IDIBAPS, Universitat de Barcelona</wicri:noRegion></affiliation></author><author><name sortKey="Dubois, Bruno" sort="Dubois, Bruno" uniqKey="Dubois B" first="Bruno" last="Dubois">Bruno Dubois</name><affiliation wicri:level="1"><inist:fA14 i1="25"><s1>INSERM U610, Pavilion Claude Bernard, Hopital de la Salpetriere</s1><s2>Paris</s2><s3>FRA</s3><sZ>23 aut.</sZ></inist:fA14><country>France</country><placeName><settlement type="city">Paris</settlement></placeName></affiliation></author></analytic><series><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno><imprint><date when="2007">2007</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Dementia</term><term>Diagnosis</term><term>Nervous system diseases</term><term>Parkinson disease</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Système nerveux pathologie</term><term>Démence</term><term>Parkinson maladie</term><term>Diagnostic</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Dementia has been increasingly more recognized to be a common feature in patients with Parkinson's disease (PD), especially in old age. Specific criteria for the clinical diagnosis of dementia associated with PD (PD-D), however, have been lacking. A Task Force, organized by the Movement Disorder Study, was charged with the development of clinical diagnostic criteria for PD-D. The Task Force members were assigned to sub-committees and performed a systematic review of the literature, based on pre-defined selection criteria, in order to identify the epidemiological, clinical, auxiliary, and pathological features of PD-D. Clinical diagnostic criteria were then developed based on these findings and group consensus. The incidence of dementia in PD is increased up to six times, point-prevelance is close to 30%, older age and akinetic-rigid form are associated with higher risk. PD-D is characterized by impairment in attention, memory, executive and visuo-spatial functions, behavioral symptoms such as affective changes, hallucinations, and apathy are frequent. There are no specific ancillary investigations for the diagnosis; the main pathological correlate is Lewy body-type degeneration in cerebral cortex and limbic structures. Based on the characteristic features associated with this condition, clinical diagnostic criteria for probable and possible PD-D are proposed.</div></front></TEI><affiliations><list><country><li>Australie</li><li>Autriche</li><li>Canada</li><li>Espagne</li><li>France</li><li>Israël</li><li>Japon</li><li>Norvège</li><li>Portugal</li><li>Royaume-Uni</li><li>Turquie</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Californie</li><li>Floride</li><li>Grand Londres</li><li>Illinois</li><li>Kentucky</li><li>Tyrol (Land)</li><li>État de New York</li></region><settlement><li>Innsbruck</li><li>Londres</li><li>Paris</li><li>Tokyo</li></settlement><orgName><li>National Hospital for Neurology and Neurosurgery</li><li>Université de médecine d'Innsbruck</li></orgName></list><tree><country name="Turquie"><noRegion><name sortKey="Emre, Murat" sort="Emre, Murat" uniqKey="Emre M" first="Murat" last="Emre">Murat Emre</name></noRegion></country><country name="Norvège"><noRegion><name sortKey="Aarsland, Dag" sort="Aarsland, Dag" uniqKey="Aarsland D" first="Dag" last="Aarsland">Dag Aarsland</name></noRegion><name sortKey="Aarsland, Dag" sort="Aarsland, Dag" uniqKey="Aarsland D" first="Dag" last="Aarsland">Dag Aarsland</name></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Brown, Richard" sort="Brown, Richard" uniqKey="Brown R" first="Richard" last="Brown">Richard Brown</name></region><name sortKey="Burn, David J" sort="Burn, David J" uniqKey="Burn D" first="David J." last="Burn">David J. Burn</name><name sortKey="Lees, Andrew" sort="Lees, Andrew" uniqKey="Lees A" first="Andrew" last="Lees">Andrew Lees (neurologue)</name><name sortKey="Mckeith, Ian" sort="Mckeith, Ian" uniqKey="Mckeith I" first="Ian" last="Mckeith">Ian Mckeith</name><name sortKey="Quinn, Niall" sort="Quinn, Niall" uniqKey="Quinn N" first="Niall" last="Quinn">Niall Quinn</name></country><country name="France"><noRegion><name sortKey="Duyckaerts, Charles" sort="Duyckaerts, Charles" uniqKey="Duyckaerts C" first="Charles" last="Duyckaerts">Charles Duyckaerts</name></noRegion><name sortKey="Dubois, Bruno" sort="Dubois, Bruno" uniqKey="Dubois B" first="Bruno" last="Dubois">Bruno Dubois</name><name sortKey="Levy, Richard" sort="Levy, Richard" uniqKey="Levy R" first="Richard" last="Levy">Richard Levy</name></country><country name="Japon"><noRegion><name sortKey="Mizuno, Yoshikino" sort="Mizuno, Yoshikino" uniqKey="Mizuno Y" first="Yoshikino" last="Mizuno">Yoshikino Mizuno</name></noRegion><name sortKey="Mizuno, Yoshikino" sort="Mizuno, Yoshikino" uniqKey="Mizuno Y" first="Yoshikino" last="Mizuno">Yoshikino Mizuno</name></country><country name="Australie"><noRegion><name sortKey="Broe, Gerald Anthony" sort="Broe, Gerald Anthony" uniqKey="Broe G" first="Gerald Anthony" last="Broe">Gerald Anthony Broe</name></noRegion><name sortKey="Broe, Gerald Anthony" sort="Broe, Gerald Anthony" uniqKey="Broe G" first="Gerald Anthony" last="Broe">Gerald Anthony Broe</name></country><country name="États-Unis"><region name="Californie"><name sortKey="Cummings, Jeffrey" sort="Cummings, Jeffrey" uniqKey="Cummings J" first="Jeffrey" last="Cummings">Jeffrey Cummings</name></region><name sortKey="Dickson, Dennis W" sort="Dickson, Dennis W" uniqKey="Dickson D" first="Dennis W." last="Dickson">Dennis W. Dickson</name><name sortKey="Goetz, Christopher" sort="Goetz, Christopher" uniqKey="Goetz C" first="Christopher" last="Goetz">Christopher Goetz</name><name sortKey="Goldman, Jennifer" sort="Goldman, Jennifer" uniqKey="Goldman J" first="Jennifer" last="Goldman">Jennifer Goldman</name><name sortKey="Litvan, Irene" sort="Litvan, Irene" uniqKey="Litvan I" first="Irene" last="Litvan">Irene Litvan</name><name sortKey="Olanow, Warren" sort="Olanow, Warren" uniqKey="Olanow W" first="Warren" last="Olanow">Warren Olanow</name></country><country name="Canada"><noRegion><name sortKey="Gauthier, Serge" sort="Gauthier, Serge" uniqKey="Gauthier S" first="Serge" last="Gauthier">Serge Gauthier</name></noRegion></country><country name="Israël"><noRegion><name sortKey="Korczyn, Amos" sort="Korczyn, Amos" uniqKey="Korczyn A" first="Amos" last="Korczyn">Amos Korczyn</name></noRegion></country><country name="Autriche"><region name="Tyrol (Land)"><name sortKey="Poewe, Werner" sort="Poewe, Werner" uniqKey="Poewe W" first="Werner" last="Poewe">Werner Poewe</name></region></country><country name="Portugal"><noRegion><name sortKey="Sampaio, Christina" sort="Sampaio, Christina" uniqKey="Sampaio C" first="Christina" last="Sampaio">Christina Sampaio</name></noRegion></country><country name="Espagne"><noRegion><name sortKey="Tolosa, Eduardo" sort="Tolosa, Eduardo" uniqKey="Tolosa E" first="Eduardo" last="Tolosa">Eduardo Tolosa</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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