MovDisordV3, Main, Merge, bibRecord, 004054

Skin Vasodilator Response to Local Heating in Multiple System Atrophy

Identifieur interne : 004054 ( Main/Merge ); précédent : 004053; suivant : 004055

Skin Vasodilator Response to Local Heating in Multiple System Atrophy

Auteurs : Yoshitaka Yamanaka [Japon] ; Masato Asahina [Japon] ; Christopher J. Mathias [Royaume-Uni] ; Yuichi Akaogi [Japon] ; Yu Koyama [Japon] ; Takamichi Hattori [Japon]

Source :

Movement disorders [ 0885-3185 ] ; 2007.

RBID : Pascal:08-0148977

Descripteurs français

Pascal (Inist)
- Atrophie multisystématisée, Pathologie du système nerveux autonome, Pathologie du système nerveux, Peau, Chauffage, Débit sanguin, Réflexe d'axone.
Wicri :
- topic : Chauffage.

English descriptors

KwdEn :
- Axon reflex, Blood flow, Diseases of the autonomic nervous system, Heating, Multiple system atrophy, Nervous system diseases, Skin.

Abstract

Local heating of nonglabrous skin increases skin blood flow (SkBF) in two phases. The initial peak (P1) is mediated by a sensory-axon reflex and the plateau phase (P2) by local production of substances such as nitric oxide. We evaluated the SkBF response to local heating in 15 multiple system atrophy (MSA) patients with autonomic failure and 12 age-matched healthy controls. The mean ratio of SkBF at PI to that at baseline (SkBF_P1/SkBF_base ratio) in MSA was significantly lower than that in controls (P < 0.01). The mean ratio of SkBF at P2 seemed to be slightly reduced in the MSA patients, compared with controls, although there was no significant difference. The P1 phase is thought to be mediated by a sensory-axon reflex modulated by sympathetic nerve activity. These findings are indicative of the skin sympathetic vasomotor dysfunction in MSA.

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Pascal:08-0148977

Le document en format XML

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<author><name sortKey="Mathias, Christopher J" sort="Mathias, Christopher J" uniqKey="Mathias C" first="Christopher J." last="Mathias">Christopher J. Mathias</name>
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<author><name sortKey="Hattori, Takamichi" sort="Hattori, Takamichi" uniqKey="Hattori T" first="Takamichi" last="Hattori">Takamichi Hattori</name>
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<author><name sortKey="Akaogi, Yuichi" sort="Akaogi, Yuichi" uniqKey="Akaogi Y" first="Yuichi" last="Akaogi">Yuichi Akaogi</name>
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<author><name sortKey="Hattori, Takamichi" sort="Hattori, Takamichi" uniqKey="Hattori T" first="Takamichi" last="Hattori">Takamichi Hattori</name>
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<series><title level="j" type="main">Movement disorders</title>
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<seriesStmt><title level="j" type="main">Movement disorders</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Axon reflex</term>
<term>Blood flow</term>
<term>Diseases of the autonomic nervous system</term>
<term>Heating</term>
<term>Multiple system atrophy</term>
<term>Nervous system diseases</term>
<term>Skin</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Atrophie multisystématisée</term>
<term>Pathologie du système nerveux autonome</term>
<term>Pathologie du   système nerveux</term>
<term>Peau</term>
<term>Chauffage</term>
<term>Débit sanguin</term>
<term>Réflexe d'axone</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Chauffage</term>
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<front><div type="abstract" xml:lang="en">Local heating of nonglabrous skin increases skin blood flow (SkBF) in two phases. The initial peak (P1) is mediated by a sensory-axon reflex and the plateau phase (P2) by local production of substances such as nitric oxide. We evaluated the SkBF response to local heating in 15 multiple system atrophy (MSA) patients with autonomic failure and 12 age-matched healthy controls. The mean ratio of SkBF at PI to that at baseline (SkBF<sub>P1</sub>
/SkBF<sub>base</sub>
 ratio) in MSA was significantly lower than that in controls (P < 0.01). The mean ratio of SkBF at P2 seemed to be slightly reduced in the MSA patients, compared with controls, although there was no significant difference. The P1 phase is thought to be mediated by a sensory-axon reflex modulated by sympathetic nerve activity. These findings are indicative of the skin sympathetic vasomotor dysfunction in MSA.</div>
</front>
</TEI>
<affiliations><list><country><li>Japon</li>
<li>Royaume-Uni</li>
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<tree><country name="Japon"><noRegion><name sortKey="Yamanaka, Yoshitaka" sort="Yamanaka, Yoshitaka" uniqKey="Yamanaka Y" first="Yoshitaka" last="Yamanaka">Yoshitaka Yamanaka</name>
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<name sortKey="Akaogi, Yuichi" sort="Akaogi, Yuichi" uniqKey="Akaogi Y" first="Yuichi" last="Akaogi">Yuichi Akaogi</name>
<name sortKey="Asahina, Masato" sort="Asahina, Masato" uniqKey="Asahina M" first="Masato" last="Asahina">Masato Asahina</name>
<name sortKey="Hattori, Takamichi" sort="Hattori, Takamichi" uniqKey="Hattori T" first="Takamichi" last="Hattori">Takamichi Hattori</name>
<name sortKey="Koyama, Yu" sort="Koyama, Yu" uniqKey="Koyama Y" first="Yu" last="Koyama">Yu Koyama</name>
</country>
<country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Mathias, Christopher J" sort="Mathias, Christopher J" uniqKey="Mathias C" first="Christopher J." last="Mathias">Christopher J. Mathias</name>
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<name sortKey="Mathias, Christopher J" sort="Mathias, Christopher J" uniqKey="Mathias C" first="Christopher J." last="Mathias">Christopher J. Mathias</name>
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</record>

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	Movement Disorders (revue)
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Movement Disorders (revue)

Skin Vasodilator Response to Local Heating in Multiple System Atrophy

Skin Vasodilator Response to Local Heating in Multiple System Atrophy

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri