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Staged unilateral versus bilateral subthalamic nucleus stimulator implantation in Parkinson disease

Identifieur interne : 004045 ( Main/Merge ); précédent : 004044; suivant : 004046

Staged unilateral versus bilateral subthalamic nucleus stimulator implantation in Parkinson disease

Auteurs : Ali Samii [États-Unis] ; Valerie E. Kelly [États-Unis] ; Jefferson C. Slimp [États-Unis] ; Anne Shumway-Cook [États-Unis] ; Robert Goodkin [États-Unis]

Source :

Movement disorders [ 0885-3185 ] ; 2007.

RBID : Pascal:07-0393270

Descripteurs français

Pascal (Inist)
- Système nerveux pathologie, Parkinson maladie, Dyskinésie, Etude comparative, Noyau sousthalamique, Stimulateur, Chirurgie, Stimulation cérébrale profonde.
Wicri :
- topic : Chirurgie.

English descriptors

KwdEn :
- Comparative study, Deep brain stimulation, Dyskinesia, Nervous system diseases, Parkinson disease, Stimulator, Subthalamic nucleus, Surgery.

Abstract

In 17 consecutive patients with Parkinson disease (PD), bilateral subthalamic nucleus (STN) stimulators were implanted during staged surgeries. The Unified Parkinson Disease Rating Scale (UPDRS) and the Dyskinesia Disability Scale were completed both off and on medication prior to any surgery and also OFF and ON stimulation after each surgery. On-medication UPDRS activities of daily living (ADL) and motor examination scores changed little with unilateral or bilateral stimulation. Off-medication UPDRS motor examination scores improved to similar degrees after each staged STN electrode implantation. Most of the improvements in off-medication ADL scores, dyskinesia scores, complications of therapy, and medication dose reduction occurred after unilateral STN stimulation with smaller improvements after the second operation.

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Pascal:07-0393270

Le document en format XML

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<author><name sortKey="Samii, Ali" sort="Samii, Ali" uniqKey="Samii A" first="Ali" last="Samii">Ali Samii</name>
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<affiliation wicri:level="2"><inist:fA14 i1="02"><s1>Parkinson Disease Research Education and Clinical Center, Neurology Section, VA Puget Sound Health Care System</s1>
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<author><name sortKey="Goodkin, Robert" sort="Goodkin, Robert" uniqKey="Goodkin R" first="Robert" last="Goodkin">Robert Goodkin</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Staged unilateral versus bilateral subthalamic nucleus stimulator implantation in Parkinson disease</title>
<author><name sortKey="Samii, Ali" sort="Samii, Ali" uniqKey="Samii A" first="Ali" last="Samii">Ali Samii</name>
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<author><name sortKey="Kelly, Valerie E" sort="Kelly, Valerie E" uniqKey="Kelly V" first="Valerie E." last="Kelly">Valerie E. Kelly</name>
<affiliation wicri:level="4"><inist:fA14 i1="03"><s1>Department of Rehabilitation Medicine, University of Washington</s1>
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<author><name sortKey="Slimp, Jefferson C" sort="Slimp, Jefferson C" uniqKey="Slimp J" first="Jefferson C." last="Slimp">Jefferson C. Slimp</name>
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<series><title level="j" type="main">Movement disorders</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Comparative study</term>
<term>Deep brain stimulation</term>
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<term>Parkinson disease</term>
<term>Stimulator</term>
<term>Subthalamic nucleus</term>
<term>Surgery</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Système nerveux pathologie</term>
<term>Parkinson maladie</term>
<term>Dyskinésie</term>
<term>Etude comparative</term>
<term>Noyau sousthalamique</term>
<term>Stimulateur</term>
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<front><div type="abstract" xml:lang="en">In 17 consecutive patients with Parkinson disease (PD), bilateral subthalamic nucleus (STN) stimulators were implanted during staged surgeries. The Unified Parkinson Disease Rating Scale (UPDRS) and the Dyskinesia Disability Scale were completed both off and on medication prior to any surgery and also OFF and ON stimulation after each surgery. On-medication UPDRS activities of daily living (ADL) and motor examination scores changed little with unilateral or bilateral stimulation. Off-medication UPDRS motor examination scores improved to similar degrees after each staged STN electrode implantation. Most of the improvements in off-medication ADL scores, dyskinesia scores, complications of therapy, and medication dose reduction occurred after unilateral STN stimulation with smaller improvements after the second operation.</div>
</front>
</TEI>
<affiliations><list><country><li>États-Unis</li>
</country>
<region><li>Washington (État)</li>
</region>
<settlement><li>Seattle</li>
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<orgName><li>Université de Washington</li>
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<tree><country name="États-Unis"><region name="Washington (État)"><name sortKey="Samii, Ali" sort="Samii, Ali" uniqKey="Samii A" first="Ali" last="Samii">Ali Samii</name>
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<name sortKey="Goodkin, Robert" sort="Goodkin, Robert" uniqKey="Goodkin R" first="Robert" last="Goodkin">Robert Goodkin</name>
<name sortKey="Kelly, Valerie E" sort="Kelly, Valerie E" uniqKey="Kelly V" first="Valerie E." last="Kelly">Valerie E. Kelly</name>
<name sortKey="Samii, Ali" sort="Samii, Ali" uniqKey="Samii A" first="Ali" last="Samii">Ali Samii</name>
<name sortKey="Shumway Cook, Anne" sort="Shumway Cook, Anne" uniqKey="Shumway Cook A" first="Anne" last="Shumway-Cook">Anne Shumway-Cook</name>
<name sortKey="Slimp, Jefferson C" sort="Slimp, Jefferson C" uniqKey="Slimp J" first="Jefferson C." last="Slimp">Jefferson C. Slimp</name>
</country>
</tree>
</affiliations>
</record>

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	Movement Disorders (revue)
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Movement Disorders (revue)

Staged unilateral versus bilateral subthalamic nucleus stimulator implantation in Parkinson disease

Staged unilateral versus bilateral subthalamic nucleus stimulator implantation in Parkinson disease

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri