Enhancement of rigidity in Parkinson's disease with activation
Identifieur interne : 003D82 ( Main/Merge ); précédent : 003D81; suivant : 003D83Enhancement of rigidity in Parkinson's disease with activation
Auteurs : Minna Hong [États-Unis] ; Joel S. Perlmutter [États-Unis] ; Gammon M. Earhart [États-Unis]Source :
- Movement Disorders [ 0885-3185 ] ; 2007-06-15.
English descriptors
- KwdEn :
- MESH :
- epidemiology : Muscle Rigidity, Parkinson Disease.
- physiopathology : Muscle Rigidity, Muscle, Skeletal, Parkinson Disease.
- Aged, Female, Humans, Male, Middle Aged.
Abstract
Rigidity, a cardinal symptom of Parkinson's disease (PD), increases with movement of a contralateral limb. It is unclear whether this effect is specific for movement of a contralateral limb. The goal of this study was to test the hypothesis that ipsilateral or contralateral movement would enhance rigidity but that bilateral limb movements would maximally increase rigidity in people with PD. We assessed rigidity in 12 people with PD off meds, 12 matched controls, and 10 young controls, using a Rigidity Analyzer (Neurokinetics, Alberta, Canada). The elbow was passively moved repetitively into flexion and extension by the examiner, while the subjects engaged in different toe tapping conditions: no tapping, ipsilateral tapping, contralateral tapping, and bilateral tapping. Three 50‐second trials were done for each condition and the order of the trials was randomized. A 2‐way repeated measures ANOVA and Holm–Sidak post hoc tests were used to determine differences across conditions and groups. There was a significant effect of group, tapping conditions and an interaction of the two. Post hoc tests revealed that for the PD group, all tapping conditions were significantly different from the no tapping condition but not different from each other. There were no differences across conditions for the controls. We conclude that movement of either the contralateral or ipsilateral lower extremity can increase arm rigidity in people with PD but the effects from left and right are apparently not additive. Further, activation did not enhance muscle tone in controls suggesting that this procedure may help distinguish people with PD from controls. © 2007 Movement Disordrer Society
Url:
DOI: 10.1002/mds.21524
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 001931
- to stream Istex, to step Curation: 001931
- to stream Istex, to step Checkpoint: 001968
- to stream PubMed, to step Corpus: 002759
- to stream PubMed, to step Curation: 002759
- to stream PubMed, to step Checkpoint: 002832
- to stream Ncbi, to step Merge: 001B80
- to stream Ncbi, to step Curation: 001B80
- to stream Ncbi, to step Checkpoint: 001B80
Links to Exploration step
ISTEX:4C632E3FD499282B7ACF26C68B6C26D6790F0E7ELe document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Enhancement of rigidity in Parkinson's disease with activation</title>
<author><name sortKey="Hong, Minna" sort="Hong, Minna" uniqKey="Hong M" first="Minna" last="Hong">Minna Hong</name>
</author>
<author><name sortKey="Perlmutter, Joel S" sort="Perlmutter, Joel S" uniqKey="Perlmutter J" first="Joel S." last="Perlmutter">Joel S. Perlmutter</name>
</author>
<author><name sortKey="Earhart, Gammon M" sort="Earhart, Gammon M" uniqKey="Earhart G" first="Gammon M." last="Earhart">Gammon M. Earhart</name>
<affiliation><country>États-Unis</country>
<placeName><settlement type="city">Saint-Louis (Missouri)</settlement>
<region type="state">Missouri (État)</region>
</placeName>
<orgName type="university" n="3">École de médecine (Université Washington de Saint-Louis)</orgName>
<orgName type="institution">Université Washington de Saint-Louis</orgName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:4C632E3FD499282B7ACF26C68B6C26D6790F0E7E</idno>
<date when="2007" year="2007">2007</date>
<idno type="doi">10.1002/mds.21524</idno>
<idno type="url">https://api.istex.fr/document/4C632E3FD499282B7ACF26C68B6C26D6790F0E7E/fulltext/pdf</idno>
<idno type="wicri:Area/Istex/Corpus">001931</idno>
<idno type="wicri:Area/Istex/Curation">001931</idno>
<idno type="wicri:Area/Istex/Checkpoint">001968</idno>
<idno type="wicri:doubleKey">0885-3185:2007:Hong M:enhancement:of:rigidity</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:17443709</idno>
<idno type="wicri:Area/PubMed/Corpus">002759</idno>
<idno type="wicri:Area/PubMed/Curation">002759</idno>
<idno type="wicri:Area/PubMed/Checkpoint">002832</idno>
<idno type="wicri:Area/Ncbi/Merge">001B80</idno>
<idno type="wicri:Area/Ncbi/Curation">001B80</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">001B80</idno>
<idno type="wicri:doubleKey">0885-3185:2007:Hong M:enhancement:of:rigidity</idno>
<idno type="wicri:Area/Main/Merge">003D82</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Enhancement of rigidity in Parkinson's disease with activation</title>
<author><name sortKey="Hong, Minna" sort="Hong, Minna" uniqKey="Hong M" first="Minna" last="Hong">Minna Hong</name>
<affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Movement Science Program, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea>
<placeName><region type="state">Missouri (État)</region>
<settlement type="city">Saint-Louis (Missouri)</settlement>
</placeName>
<orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName>
</affiliation>
<affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Program in Physical Therapy, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea>
<placeName><region type="state">Missouri (État)</region>
<settlement type="city">Saint-Louis (Missouri)</settlement>
</placeName>
<orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName>
</affiliation>
<affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea>
<placeName><region type="state">Missouri (État)</region>
<settlement type="city">Saint-Louis (Missouri)</settlement>
</placeName>
<orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName>
</affiliation>
</author>
<author><name sortKey="Perlmutter, Joel S" sort="Perlmutter, Joel S" uniqKey="Perlmutter J" first="Joel S." last="Perlmutter">Joel S. Perlmutter</name>
<affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Movement Science Program, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea>
<placeName><region type="state">Missouri (État)</region>
<settlement type="city">Saint-Louis (Missouri)</settlement>
</placeName>
<orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName>
</affiliation>
<affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Program in Physical Therapy, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea>
<placeName><region type="state">Missouri (État)</region>
<settlement type="city">Saint-Louis (Missouri)</settlement>
</placeName>
<orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName>
</affiliation>
<affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea>
<placeName><region type="state">Missouri (État)</region>
<settlement type="city">Saint-Louis (Missouri)</settlement>
</placeName>
<orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName>
</affiliation>
<affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Anatomy and Neurobiology, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea>
<placeName><region type="state">Missouri (État)</region>
<settlement type="city">Saint-Louis (Missouri)</settlement>
</placeName>
<orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName>
</affiliation>
<affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Radiology, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea>
<placeName><region type="state">Missouri (État)</region>
<settlement type="city">Saint-Louis (Missouri)</settlement>
</placeName>
<orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName>
</affiliation>
</author>
<author><name sortKey="Earhart, Gammon M" sort="Earhart, Gammon M" uniqKey="Earhart G" first="Gammon M." last="Earhart">Gammon M. Earhart</name>
<affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Movement Science Program, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea>
<placeName><region type="state">Missouri (État)</region>
<settlement type="city">Saint-Louis (Missouri)</settlement>
</placeName>
<orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName>
<placeName><settlement type="city">Saint-Louis (Missouri)</settlement>
<region type="state">Missouri (État)</region>
</placeName>
<orgName type="university" n="3">École de médecine (Université Washington de Saint-Louis)</orgName>
<orgName type="institution">Université Washington de Saint-Louis</orgName>
</affiliation>
<affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Program in Physical Therapy, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea>
<placeName><region type="state">Missouri (État)</region>
<settlement type="city">Saint-Louis (Missouri)</settlement>
</placeName>
<orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName>
<placeName><settlement type="city">Saint-Louis (Missouri)</settlement>
<region type="state">Missouri (État)</region>
</placeName>
<orgName type="university" n="3">École de médecine (Université Washington de Saint-Louis)</orgName>
<orgName type="institution">Université Washington de Saint-Louis</orgName>
</affiliation>
<affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea>
<placeName><region type="state">Missouri (État)</region>
<settlement type="city">Saint-Louis (Missouri)</settlement>
</placeName>
<orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName>
<placeName><settlement type="city">Saint-Louis (Missouri)</settlement>
<region type="state">Missouri (État)</region>
</placeName>
<orgName type="university" n="3">École de médecine (Université Washington de Saint-Louis)</orgName>
<orgName type="institution">Université Washington de Saint-Louis</orgName>
</affiliation>
<affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Anatomy and Neurobiology, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea>
<placeName><region type="state">Missouri (État)</region>
<settlement type="city">Saint-Louis (Missouri)</settlement>
</placeName>
<orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName>
<placeName><settlement type="city">Saint-Louis (Missouri)</settlement>
<region type="state">Missouri (État)</region>
</placeName>
<orgName type="university" n="3">École de médecine (Université Washington de Saint-Louis)</orgName>
<orgName type="institution">Université Washington de Saint-Louis</orgName>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Movement Disorders</title>
<title level="j" type="abbrev">Mov. Disord.</title>
<idno type="ISSN">0885-3185</idno>
<idno type="eISSN">1531-8257</idno>
<imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher>
<pubPlace>Hoboken</pubPlace>
<date type="published" when="2007-06-15">2007-06-15</date>
<biblScope unit="vol">22</biblScope>
<biblScope unit="issue">8</biblScope>
<biblScope unit="page" from="1164">1164</biblScope>
<biblScope unit="page" to="1168">1168</biblScope>
</imprint>
<idno type="ISSN">0885-3185</idno>
</series>
<idno type="istex">4C632E3FD499282B7ACF26C68B6C26D6790F0E7E</idno>
<idno type="DOI">10.1002/mds.21524</idno>
<idno type="ArticleID">MDS21524</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Muscle Rigidity (epidemiology)</term>
<term>Muscle Rigidity (physiopathology)</term>
<term>Muscle, Skeletal (physiopathology)</term>
<term>Parkinson Disease (epidemiology)</term>
<term>Parkinson Disease (physiopathology)</term>
<term>Parkinson's disease</term>
<term>activation</term>
<term>rigidity</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Muscle Rigidity</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Muscle Rigidity</term>
<term>Muscle, Skeletal</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Rigidity, a cardinal symptom of Parkinson's disease (PD), increases with movement of a contralateral limb. It is unclear whether this effect is specific for movement of a contralateral limb. The goal of this study was to test the hypothesis that ipsilateral or contralateral movement would enhance rigidity but that bilateral limb movements would maximally increase rigidity in people with PD. We assessed rigidity in 12 people with PD off meds, 12 matched controls, and 10 young controls, using a Rigidity Analyzer (Neurokinetics, Alberta, Canada). The elbow was passively moved repetitively into flexion and extension by the examiner, while the subjects engaged in different toe tapping conditions: no tapping, ipsilateral tapping, contralateral tapping, and bilateral tapping. Three 50‐second trials were done for each condition and the order of the trials was randomized. A 2‐way repeated measures ANOVA and Holm–Sidak post hoc tests were used to determine differences across conditions and groups. There was a significant effect of group, tapping conditions and an interaction of the two. Post hoc tests revealed that for the PD group, all tapping conditions were significantly different from the no tapping condition but not different from each other. There were no differences across conditions for the controls. We conclude that movement of either the contralateral or ipsilateral lower extremity can increase arm rigidity in people with PD but the effects from left and right are apparently not additive. Further, activation did not enhance muscle tone in controls suggesting that this procedure may help distinguish people with PD from controls. © 2007 Movement Disordrer Society</div>
</front>
</TEI>
<double doi="10.1002/mds.21524"><ISTEX><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Enhancement of rigidity in Parkinson's disease with activation</title>
<author><name sortKey="Hong, Minna" sort="Hong, Minna" uniqKey="Hong M" first="Minna" last="Hong">Minna Hong</name>
</author>
<author><name sortKey="Perlmutter, Joel S" sort="Perlmutter, Joel S" uniqKey="Perlmutter J" first="Joel S." last="Perlmutter">Joel S. Perlmutter</name>
</author>
<author><name sortKey="Earhart, Gammon M" sort="Earhart, Gammon M" uniqKey="Earhart G" first="Gammon M." last="Earhart">Gammon M. Earhart</name>
<affiliation><country>États-Unis</country>
<placeName><settlement type="city">Saint-Louis (Missouri)</settlement>
<region type="state">Missouri (État)</region>
</placeName>
<orgName type="university" n="3">École de médecine (Université Washington de Saint-Louis)</orgName>
<orgName type="institution">Université Washington de Saint-Louis</orgName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:4C632E3FD499282B7ACF26C68B6C26D6790F0E7E</idno>
<date when="2007" year="2007">2007</date>
<idno type="doi">10.1002/mds.21524</idno>
<idno type="url">https://api.istex.fr/document/4C632E3FD499282B7ACF26C68B6C26D6790F0E7E/fulltext/pdf</idno>
<idno type="wicri:Area/Istex/Corpus">001931</idno>
<idno type="wicri:Area/Istex/Curation">001931</idno>
<idno type="wicri:Area/Istex/Checkpoint">001968</idno>
<idno type="wicri:doubleKey">0885-3185:2007:Hong M:enhancement:of:rigidity</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Enhancement of rigidity in Parkinson's disease with activation</title>
<author><name sortKey="Hong, Minna" sort="Hong, Minna" uniqKey="Hong M" first="Minna" last="Hong">Minna Hong</name>
<affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Movement Science Program, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea>
<placeName><region type="state">Missouri (État)</region>
<settlement type="city">Saint-Louis (Missouri)</settlement>
</placeName>
<orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName>
</affiliation>
<affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Program in Physical Therapy, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea>
<placeName><region type="state">Missouri (État)</region>
<settlement type="city">Saint-Louis (Missouri)</settlement>
</placeName>
<orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName>
</affiliation>
<affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea>
<placeName><region type="state">Missouri (État)</region>
<settlement type="city">Saint-Louis (Missouri)</settlement>
</placeName>
<orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName>
</affiliation>
</author>
<author><name sortKey="Perlmutter, Joel S" sort="Perlmutter, Joel S" uniqKey="Perlmutter J" first="Joel S." last="Perlmutter">Joel S. Perlmutter</name>
<affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Movement Science Program, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea>
<placeName><region type="state">Missouri (État)</region>
<settlement type="city">Saint-Louis (Missouri)</settlement>
</placeName>
<orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName>
</affiliation>
<affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Program in Physical Therapy, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea>
<placeName><region type="state">Missouri (État)</region>
<settlement type="city">Saint-Louis (Missouri)</settlement>
</placeName>
<orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName>
</affiliation>
<affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea>
<placeName><region type="state">Missouri (État)</region>
<settlement type="city">Saint-Louis (Missouri)</settlement>
</placeName>
<orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName>
</affiliation>
<affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Anatomy and Neurobiology, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea>
<placeName><region type="state">Missouri (État)</region>
<settlement type="city">Saint-Louis (Missouri)</settlement>
</placeName>
<orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName>
</affiliation>
<affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Radiology, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea>
<placeName><region type="state">Missouri (État)</region>
<settlement type="city">Saint-Louis (Missouri)</settlement>
</placeName>
<orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName>
</affiliation>
</author>
<author><name sortKey="Earhart, Gammon M" sort="Earhart, Gammon M" uniqKey="Earhart G" first="Gammon M." last="Earhart">Gammon M. Earhart</name>
<affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Movement Science Program, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea>
<placeName><region type="state">Missouri (État)</region>
<settlement type="city">Saint-Louis (Missouri)</settlement>
</placeName>
<orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName>
<placeName><settlement type="city">Saint-Louis (Missouri)</settlement>
<region type="state">Missouri (État)</region>
</placeName>
<orgName type="university" n="3">École de médecine (Université Washington de Saint-Louis)</orgName>
<orgName type="institution">Université Washington de Saint-Louis</orgName>
</affiliation>
<affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Program in Physical Therapy, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea>
<placeName><region type="state">Missouri (État)</region>
<settlement type="city">Saint-Louis (Missouri)</settlement>
</placeName>
<orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName>
<placeName><settlement type="city">Saint-Louis (Missouri)</settlement>
<region type="state">Missouri (État)</region>
</placeName>
<orgName type="university" n="3">École de médecine (Université Washington de Saint-Louis)</orgName>
<orgName type="institution">Université Washington de Saint-Louis</orgName>
</affiliation>
<affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Neurology, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea>
<placeName><region type="state">Missouri (État)</region>
<settlement type="city">Saint-Louis (Missouri)</settlement>
</placeName>
<orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName>
<placeName><settlement type="city">Saint-Louis (Missouri)</settlement>
<region type="state">Missouri (État)</region>
</placeName>
<orgName type="university" n="3">École de médecine (Université Washington de Saint-Louis)</orgName>
<orgName type="institution">Université Washington de Saint-Louis</orgName>
</affiliation>
<affiliation wicri:level="4"><country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Anatomy and Neurobiology, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea>
<placeName><region type="state">Missouri (État)</region>
<settlement type="city">Saint-Louis (Missouri)</settlement>
</placeName>
<orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName>
<placeName><settlement type="city">Saint-Louis (Missouri)</settlement>
<region type="state">Missouri (État)</region>
</placeName>
<orgName type="university" n="3">École de médecine (Université Washington de Saint-Louis)</orgName>
<orgName type="institution">Université Washington de Saint-Louis</orgName>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Movement Disorders</title>
<title level="j" type="abbrev">Mov. Disord.</title>
<idno type="ISSN">0885-3185</idno>
<idno type="eISSN">1531-8257</idno>
<imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher>
<pubPlace>Hoboken</pubPlace>
<date type="published" when="2007-06-15">2007-06-15</date>
<biblScope unit="vol">22</biblScope>
<biblScope unit="issue">8</biblScope>
<biblScope unit="page" from="1164">1164</biblScope>
<biblScope unit="page" to="1168">1168</biblScope>
</imprint>
<idno type="ISSN">0885-3185</idno>
</series>
<idno type="istex">4C632E3FD499282B7ACF26C68B6C26D6790F0E7E</idno>
<idno type="DOI">10.1002/mds.21524</idno>
<idno type="ArticleID">MDS21524</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Parkinson's disease</term>
<term>activation</term>
<term>rigidity</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Rigidity, a cardinal symptom of Parkinson's disease (PD), increases with movement of a contralateral limb. It is unclear whether this effect is specific for movement of a contralateral limb. The goal of this study was to test the hypothesis that ipsilateral or contralateral movement would enhance rigidity but that bilateral limb movements would maximally increase rigidity in people with PD. We assessed rigidity in 12 people with PD off meds, 12 matched controls, and 10 young controls, using a Rigidity Analyzer (Neurokinetics, Alberta, Canada). The elbow was passively moved repetitively into flexion and extension by the examiner, while the subjects engaged in different toe tapping conditions: no tapping, ipsilateral tapping, contralateral tapping, and bilateral tapping. Three 50‐second trials were done for each condition and the order of the trials was randomized. A 2‐way repeated measures ANOVA and Holm–Sidak post hoc tests were used to determine differences across conditions and groups. There was a significant effect of group, tapping conditions and an interaction of the two. Post hoc tests revealed that for the PD group, all tapping conditions were significantly different from the no tapping condition but not different from each other. There were no differences across conditions for the controls. We conclude that movement of either the contralateral or ipsilateral lower extremity can increase arm rigidity in people with PD but the effects from left and right are apparently not additive. Further, activation did not enhance muscle tone in controls suggesting that this procedure may help distinguish people with PD from controls. © 2007 Movement Disordrer Society</div>
</front>
</TEI>
</ISTEX>
<PubMed><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Enhancement of rigidity in Parkinson's disease with activation.</title>
<author><name sortKey="Hong, Minna" sort="Hong, Minna" uniqKey="Hong M" first="Minna" last="Hong">Minna Hong</name>
<affiliation wicri:level="4"><nlm:affiliation>Movement Science Program, Washington University School of Medicine, St Louis, MO 63108, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Movement Science Program, Washington University School of Medicine, St Louis, MO 63108</wicri:regionArea>
<placeName><region type="state">Missouri (État)</region>
<settlement type="city">Saint-Louis (Missouri)</settlement>
</placeName>
<orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName>
</affiliation>
</author>
<author><name sortKey="Perlmutter, Joel S" sort="Perlmutter, Joel S" uniqKey="Perlmutter J" first="Joel S" last="Perlmutter">Joel S. Perlmutter</name>
</author>
<author><name sortKey="Earhart, Gammon M" sort="Earhart, Gammon M" uniqKey="Earhart G" first="Gammon M" last="Earhart">Gammon M. Earhart</name>
<affiliation><country>États-Unis</country>
<placeName><settlement type="city">Saint-Louis (Missouri)</settlement>
<region type="state">Missouri (État)</region>
</placeName>
<orgName type="university" n="3">École de médecine (Université Washington de Saint-Louis)</orgName>
<orgName type="institution">Université Washington de Saint-Louis</orgName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2007">2007</date>
<idno type="doi">10.1002/mds.21524</idno>
<idno type="RBID">pubmed:17443709</idno>
<idno type="pmid">17443709</idno>
<idno type="wicri:Area/PubMed/Corpus">002759</idno>
<idno type="wicri:Area/PubMed/Curation">002759</idno>
<idno type="wicri:Area/PubMed/Checkpoint">002832</idno>
<idno type="wicri:Area/Ncbi/Merge">001B80</idno>
<idno type="wicri:Area/Ncbi/Curation">001B80</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">001B80</idno>
<idno type="wicri:doubleKey">0885-3185:2007:Hong M:enhancement:of:rigidity</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Enhancement of rigidity in Parkinson's disease with activation.</title>
<author><name sortKey="Hong, Minna" sort="Hong, Minna" uniqKey="Hong M" first="Minna" last="Hong">Minna Hong</name>
<affiliation wicri:level="4"><nlm:affiliation>Movement Science Program, Washington University School of Medicine, St Louis, MO 63108, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Movement Science Program, Washington University School of Medicine, St Louis, MO 63108</wicri:regionArea>
<placeName><region type="state">Missouri (État)</region>
<settlement type="city">Saint-Louis (Missouri)</settlement>
</placeName>
<orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName>
</affiliation>
</author>
<author><name sortKey="Perlmutter, Joel S" sort="Perlmutter, Joel S" uniqKey="Perlmutter J" first="Joel S" last="Perlmutter">Joel S. Perlmutter</name>
</author>
<author><name sortKey="Earhart, Gammon M" sort="Earhart, Gammon M" uniqKey="Earhart G" first="Gammon M" last="Earhart">Gammon M. Earhart</name>
<affiliation><country>États-Unis</country>
<placeName><settlement type="city">Saint-Louis (Missouri)</settlement>
<region type="state">Missouri (État)</region>
</placeName>
<orgName type="university" n="3">École de médecine (Université Washington de Saint-Louis)</orgName>
<orgName type="institution">Université Washington de Saint-Louis</orgName>
</affiliation>
</author>
</analytic>
<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
<idno type="ISSN">0885-3185</idno>
<imprint><date when="2007" type="published">2007</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Muscle Rigidity (epidemiology)</term>
<term>Muscle Rigidity (physiopathology)</term>
<term>Muscle, Skeletal (physiopathology)</term>
<term>Parkinson Disease (epidemiology)</term>
<term>Parkinson Disease (physiopathology)</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Muscle Rigidity</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Muscle Rigidity</term>
<term>Muscle, Skeletal</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Rigidity, a cardinal symptom of Parkinson's disease (PD), increases with movement of a contralateral limb. It is unclear whether this effect is specific for movement of a contralateral limb. The goal of this study was to test the hypothesis that ipsilateral or contralateral movement would enhance rigidity but that bilateral limb movements would maximally increase rigidity in people with PD. We assessed rigidity in 12 people with PD off meds, 12 matched controls, and 10 young controls, using a Rigidity Analyzer (Neurokinetics, Alberta, Canada). The elbow was passively moved repetitively into flexion and extension by the examiner, while the subjects engaged in different toe tapping conditions: no tapping, ipsilateral tapping, contralateral tapping, and bilateral tapping. Three 50-second trials were done for each condition and the order of the trials was randomized. A 2-way repeated measures ANOVA and Holm-Sidak post hoc tests were used to determine differences across conditions and groups. There was a significant effect of group, tapping conditions and an interaction of the two. Post hoc tests revealed that for the PD group, all tapping conditions were significantly different from the no tapping condition but not different from each other. There were no differences across conditions for the controls. We conclude that movement of either the contralateral or ipsilateral lower extremity can increase arm rigidity in people with PD but the effects from left and right are apparently not additive. Further, activation did not enhance muscle tone in controls suggesting that this procedure may help distinguish people with PD from controls.</div>
</front>
</TEI>
</PubMed>
</double>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003D82 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 003D82 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Santé |area= MovDisordV3 |flux= Main |étape= Merge |type= RBID |clé= ISTEX:4C632E3FD499282B7ACF26C68B6C26D6790F0E7E |texte= Enhancement of rigidity in Parkinson's disease with activation }}
![]() | This area was generated with Dilib version V0.6.23. | ![]() |