Local field potentials and oscillatory activity of the internal globus pallidus in myoclonus–dystonia
Identifieur interne : 003C91 ( Main/Merge ); précédent : 003C90; suivant : 003C92Local field potentials and oscillatory activity of the internal globus pallidus in myoclonus–dystonia
Auteurs : Elisabeth M. J. Foncke [Pays-Bas] ; Lo J. Bour [Pays-Bas] ; Johannes D. Speelman [Pays-Bas] ; Johannes H. T. M. Koelman [Pays-Bas] ; Marina A. J. Tijssen [Pays-Bas]Source :
- Movement Disorders [ 0885-3185 ] ; 2007-02-15.
English descriptors
- KwdEn :
- Adolescent, Adult, Deep Brain Stimulation (methods), Dystonic Disorders (complications), Dystonic Disorders (pathology), Dystonic Disorders (surgery), Electromyography, Evoked Potentials (physiology), Evoked Potentials (radiation effects), Female, Globus Pallidus (physiopathology), Humans, Male, Myoclonus (complications), Myoclonus (pathology), Myoclonus (surgery), Periodicity, coherence analysis, internal globus pallidus, local field potentials, myoclonus–dystonia.
- MESH :
- complications : Dystonic Disorders, Myoclonus.
- methods : Deep Brain Stimulation.
- pathology : Dystonic Disorders, Myoclonus.
- physiology : Evoked Potentials.
- physiopathology : Globus Pallidus.
- radiation effects : Evoked Potentials.
- surgery : Dystonic Disorders, Myoclonus.
- Adolescent, Adult, Electromyography, Female, Humans, Male, Periodicity.
Abstract
The pathophysiology of myoclonus–dystonia (M–D), an autosomal dominantly inherited movement disorder characterized by myoclonic jerks and dystonic contractions, is largely unknown. In the present study, local field potential (LFP) activities in the globus pallidus internus (GPi) from two genetically proven M–D patients are investigated. Coherence analysis between GPi LFP activity and electromyographic muscle activity (EMG) and synchronization of GPi neuronal activity using event‐related spectral perturbation (ERSP) in a go–no‐go paradigm were studied. Significant increased coherence in the 3 to 15 Hz frequency band was detected between GPi LFP activity and several muscles, with the LFP leading the muscles. The ERSP analysis revealed synchronization in the 3 to 15 Hz frequency band within the GPi before the imperative cue of the go–no‐go task and desynchronization in the same band after the cue. The LFP recordings of the GPi in M–D show that the low‐frequency band previously described in dystonia is also involved in the dystonia plus syndrome M–D. The 3 to 15 Hz synchronization in the go–no‐go paradigm has not been described previously and may point to the existence of (myoclonus–)dystonia specific oscillatory activity in the GPi. © 2006 Movement Disorder Society
Url:
DOI: 10.1002/mds.21284
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In the present study, local field potential (LFP) activities in the globus pallidus internus (GPi) from two genetically proven M–D patients are investigated. Coherence analysis between GPi LFP activity and electromyographic muscle activity (EMG) and synchronization of GPi neuronal activity using event‐related spectral perturbation (ERSP) in a go–no‐go paradigm were studied. Significant increased coherence in the 3 to 15 Hz frequency band was detected between GPi LFP activity and several muscles, with the LFP leading the muscles. The ERSP analysis revealed synchronization in the 3 to 15 Hz frequency band within the GPi before the imperative cue of the go–no‐go task and desynchronization in the same band after the cue. The LFP recordings of the GPi in M–D show that the low‐frequency band previously described in dystonia is also involved in the dystonia plus syndrome M–D. The 3 to 15 Hz synchronization in the go–no‐go paradigm has not been described previously and may point to the existence of (myoclonus–)dystonia specific oscillatory activity in the GPi. © 2006 Movement Disorder Society</div></front></TEI><double doi="10.1002/mds.21284"><ISTEX><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Local field potentials and oscillatory activity of the internal globus pallidus in myoclonus–dystonia</title><author><name sortKey="Foncke, Elisabeth M J" sort="Foncke, Elisabeth M J" uniqKey="Foncke E" first="Elisabeth M. J." last="Foncke">Elisabeth M. J. Foncke</name></author><author><name sortKey="Bour, Lo J" sort="Bour, Lo J" uniqKey="Bour L" first="Lo J." last="Bour">Lo J. Bour</name></author><author><name sortKey="Speelman, Johannes D" sort="Speelman, Johannes D" uniqKey="Speelman J" first="Johannes D." last="Speelman">Johannes D. Speelman</name></author><author><name sortKey="Koelman, Johannes H T M" sort="Koelman, Johannes H T M" uniqKey="Koelman J" first="Johannes H. T. M." last="Koelman">Johannes H. T. M. Koelman</name></author><author><name sortKey="Tijssen, Marina A J" sort="Tijssen, Marina A J" uniqKey="Tijssen M" first="Marina A. J." last="Tijssen">Marina A. J. Tijssen</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:5EE0D92A75BD1488FFDAE1A820DB7F2D5E5F80D5</idno><date when="2007" year="2007">2007</date><idno type="doi">10.1002/mds.21284</idno><idno type="url">https://api.istex.fr/document/5EE0D92A75BD1488FFDAE1A820DB7F2D5E5F80D5/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000E31</idno><idno type="wicri:Area/Istex/Curation">000E31</idno><idno type="wicri:Area/Istex/Checkpoint">001877</idno><idno type="wicri:doubleKey">0885-3185:2007:Foncke E:local:field:potentials</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Local field potentials and oscillatory activity of the internal globus pallidus in myoclonus–dystonia</title><author><name sortKey="Foncke, Elisabeth M J" sort="Foncke, Elisabeth M J" uniqKey="Foncke E" first="Elisabeth M. J." last="Foncke">Elisabeth M. J. 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Bour</name><affiliation wicri:level="3"><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Neurology and Clinical Neurophysiology, Academic Medical Center, University of Amsterdam, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Speelman, Johannes D" sort="Speelman, Johannes D" uniqKey="Speelman J" first="Johannes D." last="Speelman">Johannes D. Speelman</name><affiliation wicri:level="3"><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Neurology and Clinical Neurophysiology, Academic Medical Center, University of Amsterdam, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Koelman, Johannes H T M" sort="Koelman, Johannes H T M" uniqKey="Koelman J" first="Johannes H. T. M." last="Koelman">Johannes H. T. M. Koelman</name><affiliation wicri:level="3"><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Neurology and Clinical Neurophysiology, Academic Medical Center, University of Amsterdam, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Tijssen, Marina A J" sort="Tijssen, Marina A J" uniqKey="Tijssen M" first="Marina A. J." last="Tijssen">Marina A. J. Tijssen</name><affiliation wicri:level="3"><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Neurology and Clinical Neurophysiology, Academic Medical Center, University of Amsterdam, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2007-02-15">2007-02-15</date><biblScope unit="vol">22</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="369">369</biblScope><biblScope unit="page" to="376">376</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">5EE0D92A75BD1488FFDAE1A820DB7F2D5E5F80D5</idno><idno type="DOI">10.1002/mds.21284</idno><idno type="ArticleID">MDS21284</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>coherence analysis</term><term>internal globus pallidus</term><term>local field potentials</term><term>myoclonus–dystonia</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The pathophysiology of myoclonus–dystonia (M–D), an autosomal dominantly inherited movement disorder characterized by myoclonic jerks and dystonic contractions, is largely unknown. In the present study, local field potential (LFP) activities in the globus pallidus internus (GPi) from two genetically proven M–D patients are investigated. Coherence analysis between GPi LFP activity and electromyographic muscle activity (EMG) and synchronization of GPi neuronal activity using event‐related spectral perturbation (ERSP) in a go–no‐go paradigm were studied. Significant increased coherence in the 3 to 15 Hz frequency band was detected between GPi LFP activity and several muscles, with the LFP leading the muscles. The ERSP analysis revealed synchronization in the 3 to 15 Hz frequency band within the GPi before the imperative cue of the go–no‐go task and desynchronization in the same band after the cue. The LFP recordings of the GPi in M–D show that the low‐frequency band previously described in dystonia is also involved in the dystonia plus syndrome M–D. The 3 to 15 Hz synchronization in the go–no‐go paradigm has not been described previously and may point to the existence of (myoclonus–)dystonia specific oscillatory activity in the GPi. © 2006 Movement Disorder Society</div></front></TEI></ISTEX><PubMed><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Local field potentials and oscillatory activity of the internal globus pallidus in myoclonus-dystonia.</title><author><name sortKey="Foncke, Elisabeth M J" sort="Foncke, Elisabeth M J" uniqKey="Foncke E" first="Elisabeth M J" last="Foncke">Elisabeth M J. Foncke</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurology and Clinical Neurophysiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Neurology and Clinical Neurophysiology, Academic Medical Center, University of Amsterdam, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Bour, Lo J" sort="Bour, Lo J" uniqKey="Bour L" first="Lo J" last="Bour">Lo J. Bour</name></author><author><name sortKey="Speelman, Johannes D" sort="Speelman, Johannes D" uniqKey="Speelman J" first="Johannes D" last="Speelman">Johannes D. Speelman</name></author><author><name sortKey="Koelman, Johannes H T M" sort="Koelman, Johannes H T M" uniqKey="Koelman J" first="Johannes H T M" last="Koelman">Johannes H T M. Koelman</name></author><author><name sortKey="Tijssen, Marina A J" sort="Tijssen, Marina A J" uniqKey="Tijssen M" first="Marina A J" last="Tijssen">Marina A J. Tijssen</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2007">2007</date><idno type="doi">10.1002/mds.21284</idno><idno type="RBID">pubmed:17216649</idno><idno type="pmid">17216649</idno><idno type="wicri:Area/PubMed/Corpus">002922</idno><idno type="wicri:Area/PubMed/Curation">002922</idno><idno type="wicri:Area/PubMed/Checkpoint">002741</idno><idno type="wicri:Area/Ncbi/Merge">001A17</idno><idno type="wicri:Area/Ncbi/Curation">001A17</idno><idno type="wicri:Area/Ncbi/Checkpoint">001A17</idno><idno type="wicri:doubleKey">0885-3185:2007:Foncke E:local:field:potentials</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Local field potentials and oscillatory activity of the internal globus pallidus in myoclonus-dystonia.</title><author><name sortKey="Foncke, Elisabeth M J" sort="Foncke, Elisabeth M J" uniqKey="Foncke E" first="Elisabeth M J" last="Foncke">Elisabeth M J. Foncke</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurology and Clinical Neurophysiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Neurology and Clinical Neurophysiology, Academic Medical Center, University of Amsterdam, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Bour, Lo J" sort="Bour, Lo J" uniqKey="Bour L" first="Lo J" last="Bour">Lo J. Bour</name></author><author><name sortKey="Speelman, Johannes D" sort="Speelman, Johannes D" uniqKey="Speelman J" first="Johannes D" last="Speelman">Johannes D. Speelman</name></author><author><name sortKey="Koelman, Johannes H T M" sort="Koelman, Johannes H T M" uniqKey="Koelman J" first="Johannes H T M" last="Koelman">Johannes H T M. Koelman</name></author><author><name sortKey="Tijssen, Marina A J" sort="Tijssen, Marina A J" uniqKey="Tijssen M" first="Marina A J" last="Tijssen">Marina A J. Tijssen</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="ISSN">0885-3185</idno><imprint><date when="2007" type="published">2007</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Deep Brain Stimulation (methods)</term><term>Dystonic Disorders (complications)</term><term>Dystonic Disorders (pathology)</term><term>Dystonic Disorders (surgery)</term><term>Electromyography</term><term>Evoked Potentials (physiology)</term><term>Evoked Potentials (radiation effects)</term><term>Female</term><term>Globus Pallidus (physiopathology)</term><term>Humans</term><term>Male</term><term>Myoclonus (complications)</term><term>Myoclonus (pathology)</term><term>Myoclonus (surgery)</term><term>Periodicity</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Dystonic Disorders</term><term>Myoclonus</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Deep Brain Stimulation</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Dystonic Disorders</term><term>Myoclonus</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Evoked Potentials</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Globus Pallidus</term></keywords><keywords scheme="MESH" qualifier="radiation effects" xml:lang="en"><term>Evoked Potentials</term></keywords><keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Dystonic Disorders</term><term>Myoclonus</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Electromyography</term><term>Female</term><term>Humans</term><term>Male</term><term>Periodicity</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The pathophysiology of myoclonus-dystonia (M-D), an autosomal dominantly inherited movement disorder characterized by myoclonic jerks and dystonic contractions, is largely unknown. In the present study, local field potential (LFP) activities in the globus pallidus internus (GPi) from two genetically proven M-D patients are investigated. Coherence analysis between GPi LFP activity and electromyographic muscle activity (EMG) and synchronization of GPi neuronal activity using event-related spectral perturbation (ERSP) in a go-no-go paradigm were studied. Significant increased coherence in the 3 to 15 Hz frequency band was detected between GPi LFP activity and several muscles, with the LFP leading the muscles. The ERSP analysis revealed synchronization in the 3 to 15 Hz frequency band within the GPi before the imperative cue of the go-no-go task and desynchronization in the same band after the cue. The LFP recordings of the GPi in M-D show that the low-frequency band previously described in dystonia is also involved in the dystonia plus syndrome M-D. The 3 to 15 Hz synchronization in the go-no-go paradigm has not been described previously and may point to the existence of (myoclonus-)dystonia specific oscillatory activity in the GPi.</div></front></TEI></PubMed></double></record>Pour manipuler ce document sous Unix (Dilib)
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