Restless Legs Syndrome in Patients with Amyotrophic Lateral Sclerosis
Identifieur interne : 002449 ( Main/Merge ); précédent : 002448; suivant : 002450Restless Legs Syndrome in Patients with Amyotrophic Lateral Sclerosis
Auteurs : Daniele Lo Coco [Italie] ; Federico Piccoli [Italie] ; Vincenzo La Bella [Italie]Source :
- Movement disorders [ 0885-3185 ] ; 2010.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
- KwdEn :
Abstract
We aimed to evaluate the frequency and determinants of restless legs syndrome (RLS) in a group of 76 patients with amyotrophic lateral sclerosis (ALS) and 100 control subjects. A diagnosis of RLS was made according to the criteria of the International RLS Study Group, and severity was assessed by the RLS severity scale. RLS was significantly more frequent in patients with ALS (ALS/ RLS+) than in control subjects (25% vs. 8%; P = 0.002). Compared with control subjects, patients with ALS/RLS+ showed shorter history of RLS complaints and higher frequency of symptoms occurrence. Moreover, compared with those without RLS, patients with ALS/RLS+ showed increased functional impairment and more often reported sleep complaints. Multivariate logistic regression confirmed the association between RLS and functional impairment. Our findings suggest that RLS should be considered as a possible cause of disrupted sleep in patients with ALS and should be specifically investigated in these patients.
Links toward previous steps (curation, corpus...)
- to stream PascalFrancis, to step Corpus: 000801
- to stream PascalFrancis, to step Curation: 002518
- to stream PascalFrancis, to step Checkpoint: 000862
Links to Exploration step
Pascal:10-0512946Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Restless Legs Syndrome in Patients with Amyotrophic Lateral Sclerosis</title><author><name sortKey="Lo Coco, Daniele" sort="Lo Coco, Daniele" uniqKey="Lo Coco D" first="Daniele" last="Lo Coco">Daniele Lo Coco</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Dipartimento Universitario di Neuroscienze Cliniche, ALS Research Center, Universitç di Palermo</s1><s3>ITA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Italie</country><wicri:noRegion>Dipartimento Universitario di Neuroscienze Cliniche, ALS Research Center, Universitç di Palermo</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Dipartimento di Neuroscienze, Sleep Disorders Clinic, Ospedale Civico-ARNAS</s1><s2>Palermo</s2><s3>ITA</s3><sZ>1 aut.</sZ></inist:fA14><country>Italie</country><wicri:noRegion>Palermo</wicri:noRegion></affiliation></author><author><name sortKey="Piccoli, Federico" sort="Piccoli, Federico" uniqKey="Piccoli F" first="Federico" last="Piccoli">Federico Piccoli</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Dipartimento Universitario di Neuroscienze Cliniche, ALS Research Center, Universitç di Palermo</s1><s3>ITA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Italie</country><wicri:noRegion>Dipartimento Universitario di Neuroscienze Cliniche, ALS Research Center, Universitç di Palermo</wicri:noRegion></affiliation></author><author><name sortKey="La Bella, Vincenzo" sort="La Bella, Vincenzo" uniqKey="La Bella V" first="Vincenzo" last="La Bella">Vincenzo La Bella</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Dipartimento Universitario di Neuroscienze Cliniche, ALS Research Center, Universitç di Palermo</s1><s3>ITA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Italie</country><wicri:noRegion>Dipartimento Universitario di Neuroscienze Cliniche, ALS Research Center, Universitç di Palermo</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">10-0512946</idno><date when="2010">2010</date><idno type="stanalyst">PASCAL 10-0512946 INIST</idno><idno type="RBID">Pascal:10-0512946</idno><idno type="wicri:Area/PascalFrancis/Corpus">000801</idno><idno type="wicri:Area/PascalFrancis/Curation">002518</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">000862</idno><idno type="wicri:doubleKey">0885-3185:2010:Lo Coco D:restless:legs:syndrome</idno><idno type="wicri:Area/Main/Merge">002449</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Restless Legs Syndrome in Patients with Amyotrophic Lateral Sclerosis</title><author><name sortKey="Lo Coco, Daniele" sort="Lo Coco, Daniele" uniqKey="Lo Coco D" first="Daniele" last="Lo Coco">Daniele Lo Coco</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Dipartimento Universitario di Neuroscienze Cliniche, ALS Research Center, Universitç di Palermo</s1><s3>ITA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Italie</country><wicri:noRegion>Dipartimento Universitario di Neuroscienze Cliniche, ALS Research Center, Universitç di Palermo</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Dipartimento di Neuroscienze, Sleep Disorders Clinic, Ospedale Civico-ARNAS</s1><s2>Palermo</s2><s3>ITA</s3><sZ>1 aut.</sZ></inist:fA14><country>Italie</country><wicri:noRegion>Palermo</wicri:noRegion></affiliation></author><author><name sortKey="Piccoli, Federico" sort="Piccoli, Federico" uniqKey="Piccoli F" first="Federico" last="Piccoli">Federico Piccoli</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Dipartimento Universitario di Neuroscienze Cliniche, ALS Research Center, Universitç di Palermo</s1><s3>ITA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Italie</country><wicri:noRegion>Dipartimento Universitario di Neuroscienze Cliniche, ALS Research Center, Universitç di Palermo</wicri:noRegion></affiliation></author><author><name sortKey="La Bella, Vincenzo" sort="La Bella, Vincenzo" uniqKey="La Bella V" first="Vincenzo" last="La Bella">Vincenzo La Bella</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Dipartimento Universitario di Neuroscienze Cliniche, ALS Research Center, Universitç di Palermo</s1><s3>ITA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Italie</country><wicri:noRegion>Dipartimento Universitario di Neuroscienze Cliniche, ALS Research Center, Universitç di Palermo</wicri:noRegion></affiliation></author></analytic><series><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno><imprint><date when="2010">2010</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Movement disorders</title><title level="j" type="abbreviated">Mov. disord.</title><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Amyotrophic lateral sclerosis</term><term>Human</term><term>Insomnia</term><term>Nervous system diseases</term><term>Restless legs syndrome</term><term>Sleep</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Syndrome des jambes sans repos</term><term>Sclérose latérale amyotrophique</term><term>Insomnie</term><term>Pathologie du système nerveux</term><term>Homme</term><term>Sommeil</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We aimed to evaluate the frequency and determinants of restless legs syndrome (RLS) in a group of 76 patients with amyotrophic lateral sclerosis (ALS) and 100 control subjects. A diagnosis of RLS was made according to the criteria of the International RLS Study Group, and severity was assessed by the RLS severity scale. RLS was significantly more frequent in patients with ALS (ALS/ RLS<sup>+</sup>) than in control subjects (25% vs. 8%; P = 0.002). Compared with control subjects, patients with ALS/RLS<sup>+</sup> showed shorter history of RLS complaints and higher frequency of symptoms occurrence. Moreover, compared with those without RLS, patients with ALS/RLS<sup>+</sup> showed increased functional impairment and more often reported sleep complaints. Multivariate logistic regression confirmed the association between RLS and functional impairment. Our findings suggest that RLS should be considered as a possible cause of disrupted sleep in patients with ALS and should be specifically investigated in these patients.</div></front></TEI><affiliations><list><country><li>Italie</li></country></list><tree><country name="Italie"><noRegion><name sortKey="Lo Coco, Daniele" sort="Lo Coco, Daniele" uniqKey="Lo Coco D" first="Daniele" last="Lo Coco">Daniele Lo Coco</name></noRegion><name sortKey="La Bella, Vincenzo" sort="La Bella, Vincenzo" uniqKey="La Bella V" first="Vincenzo" last="La Bella">Vincenzo La Bella</name><name sortKey="Lo Coco, Daniele" sort="Lo Coco, Daniele" uniqKey="Lo Coco D" first="Daniele" last="Lo Coco">Daniele Lo Coco</name><name sortKey="Piccoli, Federico" sort="Piccoli, Federico" uniqKey="Piccoli F" first="Federico" last="Piccoli">Federico Piccoli</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002449 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 002449 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= Main
|étape= Merge
|type= RBID
|clé= Pascal:10-0512946
|texte= Restless Legs Syndrome in Patients with Amyotrophic Lateral Sclerosis
}}
| This area was generated with Dilib version V0.6.23. |  |