MovDisordV3, Main, Merge, bibRecord, 001A97

Modulation of Dysarthropneumophonia by Low-Frequency STN DBS in Advanced Parkinson's Disease

Identifieur interne : 001A97 ( Main/Merge ); précédent : 001A96; suivant : 001A98

Modulation of Dysarthropneumophonia by Low-Frequency STN DBS in Advanced Parkinson's Disease

Auteurs : Caroline Moreau [France] ; Odile Pennel-Ployart [France] ; Serge Pinto [France] ; Audrey Plachez [France] ; Agnes Annic [France] ; François Viallet [France] ; Alain Destée [France] ; Luc Defebvre [France]

Source :

Movement disorders [ 0885-3185 ] ; 2011.

RBID : Pascal:11-0228395

Descripteurs français

Pascal (Inist)
- Maladie de Parkinson, Dysarthrie, Pathologie du système nerveux, Modulation, Basse fréquence, Stade avancé, Noyau sousthalamique, Stimulation cérébrale profonde.

English descriptors

KwdEn :
- Advanced stage, Deep brain stimulation, Dysarthria, Low frequency, Modulation, Nervous system diseases, Parkinson disease, Subthalamic nucleus.

Abstract

Background: Parkinsonian dysarthria (as typically characterized by hypophonia, monotony of pitch, and rhythm abnormalities) is often accompanied by gait disturbances. The long-term effect of subthalamic nucleus deep brain stimulation (STN DBS) on dysarthria remains unclear. Methods: Given STN DBS's known improvement of gait disorders, we analyzed speech intelligibility and aerodynamic and acoustic parameters in 11 advanced PD patients in three double-blind, randomized conditions: "defined Off," 60 Hz STN DBS and 130 Hz STN DBS. Results: An improvement in aerodynamic speech parameters during 60 Hz STN DBS was accompanied by significant clinical benefit. Conclusions: Chronic treatment with low-frequency STN DBS may have a beneficial impact on dysarthropneumophonia, even in advanced PD patients.

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Pascal:11-0228395

Le document en format XML

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<series><title level="j" type="main">Movement disorders</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Advanced stage</term>
<term>Deep brain stimulation</term>
<term>Dysarthria</term>
<term>Low frequency</term>
<term>Modulation</term>
<term>Nervous system diseases</term>
<term>Parkinson disease</term>
<term>Subthalamic nucleus</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Maladie de Parkinson</term>
<term>Dysarthrie</term>
<term>Pathologie du   système nerveux</term>
<term>Modulation</term>
<term>Basse fréquence</term>
<term>Stade avancé</term>
<term>Noyau sousthalamique</term>
<term>Stimulation cérébrale profonde</term>
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<front><div type="abstract" xml:lang="en">Background: Parkinsonian dysarthria (as typically characterized by hypophonia, monotony of pitch, and rhythm abnormalities) is often accompanied by gait disturbances. The long-term effect of subthalamic nucleus deep brain stimulation (STN DBS) on dysarthria remains unclear. Methods: Given STN DBS's known improvement of gait disorders, we analyzed speech intelligibility and aerodynamic and acoustic parameters in 11 advanced PD patients in three double-blind, randomized conditions: "defined Off," 60 Hz STN DBS and 130 Hz STN DBS. Results: An improvement in aerodynamic speech parameters during 60 Hz STN DBS was accompanied by significant clinical benefit. Conclusions: Chronic treatment with low-frequency STN DBS may have a beneficial impact on dysarthropneumophonia, even in advanced PD patients.</div>
</front>
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<name sortKey="Defebvre, Luc" sort="Defebvre, Luc" uniqKey="Defebvre L" first="Luc" last="Defebvre">Luc Defebvre</name>
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<name sortKey="Pinto, Serge" sort="Pinto, Serge" uniqKey="Pinto S" first="Serge" last="Pinto">Serge Pinto</name>
<name sortKey="Plachez, Audrey" sort="Plachez, Audrey" uniqKey="Plachez A" first="Audrey" last="Plachez">Audrey Plachez</name>
<name sortKey="Viallet, Francois" sort="Viallet, Francois" uniqKey="Viallet F" first="François" last="Viallet">François Viallet</name>
<name sortKey="Viallet, Francois" sort="Viallet, Francois" uniqKey="Viallet F" first="François" last="Viallet">François Viallet</name>
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	Movement Disorders (revue)
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Movement Disorders (revue)

Modulation of Dysarthropneumophonia by Low-Frequency STN DBS in Advanced Parkinson's Disease

Modulation of Dysarthropneumophonia by Low-Frequency STN DBS in Advanced Parkinson's Disease

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Abstract

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