Movement Disorders (revue)

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Midbrain tremor and hypertrophic olivary degeneration after pontine hemorrhage

Identifieur interne : 005307 ( Main/Exploration ); précédent : 005306; suivant : 005308

Midbrain tremor and hypertrophic olivary degeneration after pontine hemorrhage

Auteurs : Gordon M. G. Shepherd [Norvège] ; Tauböll [Norvège] ; Sören Jacob Bakke [Norvège] ; Rolf Nyberg-Hansen [Norvège]

Source :

RBID : ISTEX:0F9C3245395222EFDE594B546C59721BCFB0B8F6

Descripteurs français

English descriptors

Abstract

A severe rest tremor arose in a patient's right arm 9 months after a pontine tegmental hemorrhage. Magnetic resonance studies at 4 and 10 months showed residual hemosiderin in the pons and increasing hypertrophic olivary degeneration (HOD) affecting primarily the left olive. The tremor was refractory to pharmacotherapy (clonazepam, propranolol, and levodopa), but was reduced after implantation of a thalamic stimulator device. Although pontine hemorrhage is among several common causes of HOD, it has not previously been appreciated as a cause of midbrain (“rubral”) tremor. A disynaptic dentatorubroolivary tract associated with tremor and a monosynaptic dentatoolivary tract associated with HOD may both be components of the rubro‐olivocerebellorubral loop implicated in midbrain tremor. Their proximity makes the combination of tremor and HOD after pontine tegmental damage plausible and even likely.

Url:
DOI: 10.1002/mds.870120327


Affiliations:


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Le document en format XML

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<term>Antiparkinson Agents (therapeutic use)</term>
<term>Case study</term>
<term>Cerebral Hemorrhage (complications)</term>
<term>Cerebral Hemorrhage (diagnosis)</term>
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