Coffee and tea consumption and the risk of Parkinson's disease
Identifieur interne : 002F50 ( Main/Exploration ); précédent : 002F49; suivant : 002F51Coffee and tea consumption and the risk of Parkinson's disease
Auteurs : Gang Hu [Finlande] ; Siamak Bidel [Finlande] ; Pekka Jousilahti [Finlande] ; Riitta Antikainen [Finlande] ; Jaakko Tuomilehto [Finlande]Source :
- Movement Disorders [ 0885-3185 ] ; 2007-11-15.
Descripteurs français
- Wicri :
- geographic : Finlande.
English descriptors
- KwdEn :
- MESH :
- chemical : Coffee, Tea.
- geographic , epidemiology : Finland.
- epidemiology : Parkinson Disease.
- Adult, Female, Food Habits, Humans, Incidence, Male, Middle Aged, Prejudice, Prospective Studies, Questionnaires, Risk Factors, Risk Reduction Behavior.
Abstract
Several prospective studies have assessed the association between coffee consumption and Parkinson's disease (PD) risk, but the results are inconsistent. We examined the association of coffee and tea consumption with the risk of incident PD among 29,335 Finnish subjects aged 25 to 74 years without a history of PD at baseline. During a mean follow‐up of 12.9 years, 102 men and 98 women developed an incident PD. The multivariate‐adjusted (age, body mass index, systolic blood pressure, total cholesterol, education, leisure‐time physical activity, smoking, alcohol and tea consumption, and history of diabetes) hazard ratios (HRs) of PD associated with the amount of coffee consumed daily (0, 1–4, and ≥5 cups) were 1.00, 0.55, and 0.41 (P for trend = 0.063) in men, 1.00, 0.50, and 0.39 (P for trend = 0.073) in women, and 1.00, 0.53, and 0.40 (P for trend = 0.005) in men and women combined (adjusted also for sex), respectively. In both sexes combined, the multivariate‐adjusted HRs of PD for subjects drinking ≥3 cups of tea daily compared with tea nondrinkers was 0.41 (95% CI 0.20–0.83). These results suggest that coffee drinking is associated with a lower risk of PD. More tea drinking is associated with a lower risk of PD. © 2007 Movement Disorder Society
Url:
DOI: 10.1002/mds.21706
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">Several prospective studies have assessed the association between coffee consumption and Parkinson's disease (PD) risk, but the results are inconsistent. We examined the association of coffee and tea consumption with the risk of incident PD among 29,335 Finnish subjects aged 25 to 74 years without a history of PD at baseline. During a mean follow‐up of 12.9 years, 102 men and 98 women developed an incident PD. The multivariate‐adjusted (age, body mass index, systolic blood pressure, total cholesterol, education, leisure‐time physical activity, smoking, alcohol and tea consumption, and history of diabetes) hazard ratios (HRs) of PD associated with the amount of coffee consumed daily (0, 1–4, and ≥5 cups) were 1.00, 0.55, and 0.41 (P for trend = 0.063) in men, 1.00, 0.50, and 0.39 (P for trend = 0.073) in women, and 1.00, 0.53, and 0.40 (P for trend = 0.005) in men and women combined (adjusted also for sex), respectively. In both sexes combined, the multivariate‐adjusted HRs of PD for subjects drinking ≥3 cups of tea daily compared with tea nondrinkers was 0.41 (95% CI 0.20–0.83). These results suggest that coffee drinking is associated with a lower risk of PD. More tea drinking is associated with a lower risk of PD. © 2007 Movement Disorder Society</div>
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