Movement Disorders (revue)

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Cardiac 123I-MIBG scintigraphy in patients with essential tremor

Identifieur interne : 003665 ( Main/Exploration ); précédent : 003664; suivant : 003666

Cardiac 123I-MIBG scintigraphy in patients with essential tremor

Auteurs : PHIL HYU LEE [Corée du Sud] ; JI WON KIM [Corée du Sud] ; OH YOUNG BANG [Corée du Sud] ; IN SOO JOO [Corée du Sud] ; Seok-Nam Yoon [Corée du Sud] ; Kyoon Huh [Corée du Sud]

Source :

RBID : Pascal:06-0435101

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English descriptors

Abstract

In some cases, it is difficult to differentiate essential tremor (ET) from Parkinson's disease (PD), especially in the early stages of the disease. We investigated cardiac sympathetic dysfunction using 123I-metaiodobenzylguanidine (MIBG) myocardial scintigraphy in 22 patients with ET, in comparison with early PD and tremor-dominant PD (TDPD). The mean ratio of 123I-MIBG uptake in the region of interest in the heart to that in the mediastinum (H/M ratio) was significantly greater in patients with ET (1.99 ± 0.21) than in those with either TDPD (1.28 ± 0.11) or early PD (1.28 ± 0.17; each P < 0.001). The H/M ratio in all patients with ET was greater than two standard deviations above the range of the ratio in the patients with early PD or TDPD.


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Le document en format XML

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I-MIBG scintigraphy in patients with essential tremor</title>
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<title xml:lang="en" level="a">Cardiac
<sup>123</sup>
I-MIBG scintigraphy in patients with essential tremor</title>
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<div type="abstract" xml:lang="en">In some cases, it is difficult to differentiate essential tremor (ET) from Parkinson's disease (PD), especially in the early stages of the disease. We investigated cardiac sympathetic dysfunction using
<sup>123</sup>
I-metaiodobenzylguanidine (MIBG) myocardial scintigraphy in 22 patients with ET, in comparison with early PD and tremor-dominant PD (TDPD). The mean ratio of
<sup>123</sup>
I-MIBG uptake in the region of interest in the heart to that in the mediastinum (H/M ratio) was significantly greater in patients with ET (1.99 ± 0.21) than in those with either TDPD (1.28 ± 0.11) or early PD (1.28 ± 0.17; each P < 0.001). The H/M ratio in all patients with ET was greater than two standard deviations above the range of the ratio in the patients with early PD or TDPD.</div>
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<name sortKey="Phil Hyu Lee" sort="Phil Hyu Lee" uniqKey="Phil Hyu Lee" last="Phil Hyu Lee">PHIL HYU LEE</name>
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<name sortKey="Huh, Kyoon" sort="Huh, Kyoon" uniqKey="Huh K" first="Kyoon" last="Huh">Kyoon Huh</name>
<name sortKey="In Soo Joo" sort="In Soo Joo" uniqKey="In Soo Joo" last="In Soo Joo">IN SOO JOO</name>
<name sortKey="Ji Won Kim" sort="Ji Won Kim" uniqKey="Ji Won Kim" last="Ji Won Kim">JI WON KIM</name>
<name sortKey="Oh Young Bang" sort="Oh Young Bang" uniqKey="Oh Young Bang" last="Oh Young Bang">OH YOUNG BANG</name>
<name sortKey="Yoon, Seok Nam" sort="Yoon, Seok Nam" uniqKey="Yoon S" first="Seok-Nam" last="Yoon">Seok-Nam Yoon</name>
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