Three‐dimensional gait biomechanics in Parkinson's disease: Evidence for a centrally mediated amplitude regulation disorder
Identifieur interne : 003704 ( Main/Exploration ); précédent : 003703; suivant : 003705Three‐dimensional gait biomechanics in Parkinson's disease: Evidence for a centrally mediated amplitude regulation disorder
Auteurs : Meg Morris [Australie] ; Robert Iansek [Australie] ; Jennifer Mcginley [Australie] ; Thomas Matyas [Australie] ; Frances Huxham [Australie]Source :
- Movement Disorders [ 0885-3185 ] ; 2005-01.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- Aged, Amplitude, Ankle Joint (drug effects), Ankle Joint (physiopathology), Antiparkinson Agents (therapeutic use), Biomechanical Phenomena (methods), Biomechanics, Cues, Female, Gait Disorders, Neurologic (drug therapy), Gait Disorders, Neurologic (etiology), Hip (physiopathology), Humans, Knee (physiopathology), Levodopa, Levodopa (therapeutic use), L‐dopa, Male, Middle Aged, Nervous system diseases, Parkinson Disease (drug therapy), Parkinson Disease (physiopathology), Parkinson disease, Parkinson's disease, Psychomotor Performance (drug effects), Psychomotor Performance (physiology), Treatment, biomechanics, gait, physical therapy.
- MESH :
- chemical , therapeutic use : Antiparkinson Agents, Levodopa.
- drug effects : Ankle Joint, Psychomotor Performance.
- drug therapy : Gait Disorders, Neurologic, Parkinson Disease.
- etiology : Gait Disorders, Neurologic.
- methods : Biomechanical Phenomena.
- physiology : Psychomotor Performance.
- physiopathology : Ankle Joint, Hip, Knee, Parkinson Disease.
- Aged, Cues, Female, Humans, Male, Middle Aged.
Abstract
We examined whether people with Parkinson's disease (PD) have a central amplitude regulation disorder using three‐dimensional (3‐D) gait analyses to compare the effects of medication and attentional strategies on gait in 12 PD subjects and 12 matched comparison subjects. Subjects with PD first performed several 10‐m gait trials at preferred speed while off levodopa. They then walked at preferred speed on levodopa; off levodopa with cues; and on levodopa with cues. Control subjects walked at preferred speed and then with visual cues to match their stride length to PD values. As well as spatiotemporal footstep data, pelvic and lower limb kinematic profiles and angle–angle diagrams were produced for sagittal, coronal, and transverse plane movements using a 3‐D motion analysis system. In people with PD, decreased step length was accompanied by reduced movement amplitude across all lower limb joints, in all movement planes. When control subjects were required to walk with short steps matched to the size of PD comparisons, they displayed a similar multijoint reduction in amplitude. For PD subjects, both levodopa and visual cues increased movement amplitude across all lower limb joints. Amplitude increased further when levodopa and visual cues were combined, resulting in normalization of step length. This finding suggested that reduced step length is due to a mismatch between cortically selected movement amplitude and basal ganglia maintenance mechanisms. Levodopa and cues normalized amplitude across all joints by altering motor set and bypassing defective basal ganglia mechanisms. © 2004 Movement Disorder Society
Url:
DOI: 10.1002/mds.20278
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000181
- to stream Istex, to step Curation: 000181
- to stream Istex, to step Checkpoint: 002110
- to stream PubMed, to step Corpus: 003280
- to stream PubMed, to step Curation: 003280
- to stream PubMed, to step Checkpoint: 002F36
- to stream Ncbi, to step Merge: 001008
- to stream Ncbi, to step Curation: 001008
- to stream Ncbi, to step Checkpoint: 001008
- to stream Main, to step Merge: 004D87
- to stream PascalFrancis, to step Corpus: 001F55
- to stream PascalFrancis, to step Curation: 000D66
- to stream PascalFrancis, to step Checkpoint: 001C91
- to stream Main, to step Merge: 005169
- to stream Main, to step Curation: 003704
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Three‐dimensional gait biomechanics in Parkinson's disease: Evidence for a centrally mediated amplitude regulation disorder</title>
<author><name sortKey="Morris, Meg" sort="Morris, Meg" uniqKey="Morris M" first="Meg" last="Morris">Meg Morris</name>
</author>
<author><name sortKey="Iansek, Robert" sort="Iansek, Robert" uniqKey="Iansek R" first="Robert" last="Iansek">Robert Iansek</name>
</author>
<author><name sortKey="Mcginley, Jennifer" sort="Mcginley, Jennifer" uniqKey="Mcginley J" first="Jennifer" last="Mcginley">Jennifer Mcginley</name>
</author>
<author><name sortKey="Matyas, Thomas" sort="Matyas, Thomas" uniqKey="Matyas T" first="Thomas" last="Matyas">Thomas Matyas</name>
</author>
<author><name sortKey="Huxham, Frances" sort="Huxham, Frances" uniqKey="Huxham F" first="Frances" last="Huxham">Frances Huxham</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:D949C7D4225436B2B679CE9A7C62E3820E07A02F</idno>
<date when="2005" year="2005">2005</date>
<idno type="doi">10.1002/mds.20278</idno>
<idno type="url">https://api.istex.fr/document/D949C7D4225436B2B679CE9A7C62E3820E07A02F/fulltext/pdf</idno>
<idno type="wicri:Area/Istex/Corpus">000181</idno>
<idno type="wicri:Area/Istex/Curation">000181</idno>
<idno type="wicri:Area/Istex/Checkpoint">002110</idno>
<idno type="wicri:doubleKey">0885-3185:2005:Morris M:three:dimensional:gait</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:15390033</idno>
<idno type="wicri:Area/PubMed/Corpus">003280</idno>
<idno type="wicri:Area/PubMed/Curation">003280</idno>
<idno type="wicri:Area/PubMed/Checkpoint">002F36</idno>
<idno type="wicri:Area/Ncbi/Merge">001008</idno>
<idno type="wicri:Area/Ncbi/Curation">001008</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">001008</idno>
<idno type="wicri:doubleKey">0885-3185:2005:Morris M:three:dimensional:gait</idno>
<idno type="wicri:Area/Main/Merge">004D87</idno>
<idno type="wicri:source">INIST</idno>
<idno type="RBID">Pascal:05-0172411</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">001F55</idno>
<idno type="wicri:Area/PascalFrancis/Curation">000D66</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">001C91</idno>
<idno type="wicri:doubleKey">0885-3185:2005:Morris M:three:dimensional:gait</idno>
<idno type="wicri:Area/Main/Merge">005169</idno>
<idno type="wicri:Area/Main/Curation">003704</idno>
<idno type="wicri:Area/Main/Exploration">003704</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Three‐dimensional gait biomechanics in Parkinson's disease: Evidence for a centrally mediated amplitude regulation disorder</title>
<author><name sortKey="Morris, Meg" sort="Morris, Meg" uniqKey="Morris M" first="Meg" last="Morris">Meg Morris</name>
<affiliation wicri:level="1"><country xml:lang="fr">Australie</country>
<wicri:regionArea>School of Physiotherapy, Faculty of Health Sciences, La Trobe University, Melbourne, Victoria</wicri:regionArea>
<wicri:noRegion>Victoria</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Iansek, Robert" sort="Iansek, Robert" uniqKey="Iansek R" first="Robert" last="Iansek">Robert Iansek</name>
<affiliation wicri:level="1"><country xml:lang="fr">Australie</country>
<wicri:regionArea>School of Physiotherapy, Faculty of Health Sciences, La Trobe University, Melbourne, Victoria</wicri:regionArea>
<wicri:noRegion>Victoria</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><country xml:lang="fr">Australie</country>
<wicri:regionArea>Geriatric Research Unit, Kingston Centre, Southern Health, Cheltenham, Victoria</wicri:regionArea>
<wicri:noRegion>Victoria</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mcginley, Jennifer" sort="Mcginley, Jennifer" uniqKey="Mcginley J" first="Jennifer" last="Mcginley">Jennifer Mcginley</name>
<affiliation wicri:level="1"><country xml:lang="fr">Australie</country>
<wicri:regionArea>School of Physiotherapy, Faculty of Health Sciences, La Trobe University, Melbourne, Victoria</wicri:regionArea>
<wicri:noRegion>Victoria</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><country xml:lang="fr">Australie</country>
<wicri:regionArea>Geriatric Research Unit, Kingston Centre, Southern Health, Cheltenham, Victoria</wicri:regionArea>
<wicri:noRegion>Victoria</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Matyas, Thomas" sort="Matyas, Thomas" uniqKey="Matyas T" first="Thomas" last="Matyas">Thomas Matyas</name>
<affiliation wicri:level="1"><country xml:lang="fr">Australie</country>
<wicri:regionArea>School of Psychology, Faculty of Science and Technology, La Trobe University, Melbourne, Victoria</wicri:regionArea>
<wicri:noRegion>Victoria</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Huxham, Frances" sort="Huxham, Frances" uniqKey="Huxham F" first="Frances" last="Huxham">Frances Huxham</name>
<affiliation wicri:level="1"><country xml:lang="fr">Australie</country>
<wicri:regionArea>School of Physiotherapy, Faculty of Health Sciences, La Trobe University, Melbourne, Victoria</wicri:regionArea>
<wicri:noRegion>Victoria</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><country xml:lang="fr">Australie</country>
<wicri:regionArea>Geriatric Research Unit, Kingston Centre, Southern Health, Cheltenham, Victoria</wicri:regionArea>
<wicri:noRegion>Victoria</wicri:noRegion>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Movement Disorders</title>
<title level="j" type="sub">Official Journal of the Movement Disorder Society</title>
<title level="j" type="abbrev">Mov. Disord.</title>
<idno type="ISSN">0885-3185</idno>
<idno type="eISSN">1531-8257</idno>
<imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher>
<pubPlace>Hoboken</pubPlace>
<date type="published" when="2005-01">2005-01</date>
<biblScope unit="vol">20</biblScope>
<biblScope unit="issue">1</biblScope>
<biblScope unit="page" from="40">40</biblScope>
<biblScope unit="page" to="50">50</biblScope>
</imprint>
<idno type="ISSN">0885-3185</idno>
</series>
<idno type="istex">D949C7D4225436B2B679CE9A7C62E3820E07A02F</idno>
<idno type="DOI">10.1002/mds.20278</idno>
<idno type="ArticleID">MDS20278</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term>
<term>Amplitude</term>
<term>Ankle Joint (drug effects)</term>
<term>Ankle Joint (physiopathology)</term>
<term>Antiparkinson Agents (therapeutic use)</term>
<term>Biomechanical Phenomena (methods)</term>
<term>Biomechanics</term>
<term>Cues</term>
<term>Female</term>
<term>Gait Disorders, Neurologic (drug therapy)</term>
<term>Gait Disorders, Neurologic (etiology)</term>
<term>Hip (physiopathology)</term>
<term>Humans</term>
<term>Knee (physiopathology)</term>
<term>Levodopa</term>
<term>Levodopa (therapeutic use)</term>
<term>L‐dopa</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Nervous system diseases</term>
<term>Parkinson Disease (drug therapy)</term>
<term>Parkinson Disease (physiopathology)</term>
<term>Parkinson disease</term>
<term>Parkinson's disease</term>
<term>Psychomotor Performance (drug effects)</term>
<term>Psychomotor Performance (physiology)</term>
<term>Treatment</term>
<term>biomechanics</term>
<term>gait</term>
<term>physical therapy</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antiparkinson Agents</term>
<term>Levodopa</term>
</keywords>
<keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Ankle Joint</term>
<term>Psychomotor Performance</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Gait Disorders, Neurologic</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Gait Disorders, Neurologic</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Biomechanical Phenomena</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Psychomotor Performance</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Ankle Joint</term>
<term>Hip</term>
<term>Knee</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Cues</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Amplitude</term>
<term>Biomécanique</term>
<term>Lévodopa</term>
<term>Parkinson maladie</term>
<term>Système nerveux pathologie</term>
<term>Traitement</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">We examined whether people with Parkinson's disease (PD) have a central amplitude regulation disorder using three‐dimensional (3‐D) gait analyses to compare the effects of medication and attentional strategies on gait in 12 PD subjects and 12 matched comparison subjects. Subjects with PD first performed several 10‐m gait trials at preferred speed while off levodopa. They then walked at preferred speed on levodopa; off levodopa with cues; and on levodopa with cues. Control subjects walked at preferred speed and then with visual cues to match their stride length to PD values. As well as spatiotemporal footstep data, pelvic and lower limb kinematic profiles and angle–angle diagrams were produced for sagittal, coronal, and transverse plane movements using a 3‐D motion analysis system. In people with PD, decreased step length was accompanied by reduced movement amplitude across all lower limb joints, in all movement planes. When control subjects were required to walk with short steps matched to the size of PD comparisons, they displayed a similar multijoint reduction in amplitude. For PD subjects, both levodopa and visual cues increased movement amplitude across all lower limb joints. Amplitude increased further when levodopa and visual cues were combined, resulting in normalization of step length. This finding suggested that reduced step length is due to a mismatch between cortically selected movement amplitude and basal ganglia maintenance mechanisms. Levodopa and cues normalized amplitude across all joints by altering motor set and bypassing defective basal ganglia mechanisms. © 2004 Movement Disorder Society</div>
</front>
</TEI>
<affiliations><list><country><li>Australie</li>
</country>
</list>
<tree><country name="Australie"><noRegion><name sortKey="Morris, Meg" sort="Morris, Meg" uniqKey="Morris M" first="Meg" last="Morris">Meg Morris</name>
</noRegion>
<name sortKey="Huxham, Frances" sort="Huxham, Frances" uniqKey="Huxham F" first="Frances" last="Huxham">Frances Huxham</name>
<name sortKey="Huxham, Frances" sort="Huxham, Frances" uniqKey="Huxham F" first="Frances" last="Huxham">Frances Huxham</name>
<name sortKey="Iansek, Robert" sort="Iansek, Robert" uniqKey="Iansek R" first="Robert" last="Iansek">Robert Iansek</name>
<name sortKey="Iansek, Robert" sort="Iansek, Robert" uniqKey="Iansek R" first="Robert" last="Iansek">Robert Iansek</name>
<name sortKey="Matyas, Thomas" sort="Matyas, Thomas" uniqKey="Matyas T" first="Thomas" last="Matyas">Thomas Matyas</name>
<name sortKey="Mcginley, Jennifer" sort="Mcginley, Jennifer" uniqKey="Mcginley J" first="Jennifer" last="Mcginley">Jennifer Mcginley</name>
<name sortKey="Mcginley, Jennifer" sort="Mcginley, Jennifer" uniqKey="Mcginley J" first="Jennifer" last="Mcginley">Jennifer Mcginley</name>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003704 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 003704 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Santé |area= MovDisordV3 |flux= Main |étape= Exploration |type= RBID |clé= ISTEX:D949C7D4225436B2B679CE9A7C62E3820E07A02F |texte= Three‐dimensional gait biomechanics in Parkinson's disease: Evidence for a centrally mediated amplitude regulation disorder }}
![]() | This area was generated with Dilib version V0.6.23. | ![]() |