Loss of nocturnal blood pressure fall in various extrapyramidal syndromes
Identifieur interne : 002224 ( Main/Exploration ); précédent : 002223; suivant : 002225Loss of nocturnal blood pressure fall in various extrapyramidal syndromes
Auteurs : Claudia Schmidt [Allemagne] ; Daniela Berg [Allemagne] ; Herting [Allemagne] ; Silke Prieur [Allemagne] ; Susann Junghanns [Allemagne] ; Katherine Schweitzer [Allemagne] ; Christoph Globas [Allemagne] ; Ludger Schöls [Allemagne] ; Heinz Reichmann [Allemagne] ; Tjalf Ziemssen [Allemagne]Source :
- Movement Disorders [ 0885-3185 ] ; 2009-10-30.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- Aged, Ambulatory, Arterial pressure, Autonomic Nervous System (physiopathology), Autonomic Nervous System Diseases (physiopathology), Basal Ganglia Diseases (physiopathology), Blood Pressure (physiology), Blood Pressure Monitoring, Ambulatory, Blood loss, Blood pressure, Circadian Rhythm (physiology), Cross-Sectional Studies, Dysfunction, Extrapyramidal syndrome, Female, Heart Rate (physiology), Humans, Hypertension (complications), Hypertension (physiopathology), Male, Middle Aged, Multiple System Atrophy (complications), Multiple System Atrophy (drug therapy), Multiple System Atrophy (physiopathology), Multiple system atrophy, Nervous system diseases, Parkinson Disease (complications), Parkinson Disease (drug therapy), Parkinson Disease (physiopathology), Parkinson disease, Parkinson's disease, Supranuclear Palsy, Progressive (complications), Supranuclear Palsy, Progressive (drug therapy), Supranuclear Palsy, Progressive (physiopathology), Tilt-Table Test, ambulatory blood pressure, autonomic dysfunction, multiple system atrophy, progressive supranuclear palsy.
- MESH :
- complications : Hypertension, Multiple System Atrophy, Parkinson Disease, Supranuclear Palsy, Progressive.
- drug therapy : Multiple System Atrophy, Parkinson Disease, Supranuclear Palsy, Progressive.
- physiology : Blood Pressure, Circadian Rhythm, Heart Rate.
- physiopathology : Autonomic Nervous System, Autonomic Nervous System Diseases, Basal Ganglia Diseases, Hypertension, Multiple System Atrophy, Parkinson Disease, Supranuclear Palsy, Progressive.
- Aged, Blood Pressure Monitoring, Ambulatory, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Tilt-Table Test.
Abstract
Cardiovascular autonomic dysfunction has frequently been reported in some patients with extrapyramidal syndromes, especially multiple system atrophy (MSA) but also Parkinson's disease (PD). However, there are only few reports on the prevalence of cardiovascular autonomic dysfunction progressive in supranuclear palsy (PSP). Moreover, the relation of detailed cardiovascular testing and easy to assess 24‐hour ambulatory blood pressure (BP) is not known. Our study evaluates 24‐hour ambulatory BP monitoring in patients with PD, PSP, MSA, and corresponding controls (Con) and relates the findings to the results of comprehensive cardiovascular autonomic testing. Twenty‐three patients with PD, 25 patients with PSP, 25 patients with MSA, and 26 corresponding controls were studied by 24‐hour ambulatory BP monitoring (ABPM) in comparison to cardiovascular autonomic testing. Patients with PD, PSP, and MSA presented frequently with a pathological nocturnal BP regulation (no decrease or even an increase of nocturnal BP) in comparison to the control group (PD 48%, PSP 40%, MSA 68% vs. Con 8%). In MSA and PD patients, the frequent pathological BP increase during night was closely correlated to orthostatic hypotension. Since loss of nocturnal BP fall is frequent in patients with extrapyramidal syndromes, even if they are free of subjective autonomic dysfunction, we recommend 24‐hour ABPM as an easy to perform screening test, especially if detailed autonomic testing is not available. Pathological loss of nocturnal BP fall may account for increased cardiovascular mortality in extrapyramidal syndromes. © 2009 Movement Disorder Society
Url:
DOI: 10.1002/mds.22767
Affiliations:
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<term>Ambulatory</term>
<term>Arterial pressure</term>
<term>Autonomic Nervous System (physiopathology)</term>
<term>Autonomic Nervous System Diseases (physiopathology)</term>
<term>Basal Ganglia Diseases (physiopathology)</term>
<term>Blood Pressure (physiology)</term>
<term>Blood Pressure Monitoring, Ambulatory</term>
<term>Blood loss</term>
<term>Blood pressure</term>
<term>Circadian Rhythm (physiology)</term>
<term>Cross-Sectional Studies</term>
<term>Dysfunction</term>
<term>Extrapyramidal syndrome</term>
<term>Female</term>
<term>Heart Rate (physiology)</term>
<term>Humans</term>
<term>Hypertension (complications)</term>
<term>Hypertension (physiopathology)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Multiple System Atrophy (complications)</term>
<term>Multiple System Atrophy (drug therapy)</term>
<term>Multiple System Atrophy (physiopathology)</term>
<term>Multiple system atrophy</term>
<term>Nervous system diseases</term>
<term>Parkinson Disease (complications)</term>
<term>Parkinson Disease (drug therapy)</term>
<term>Parkinson Disease (physiopathology)</term>
<term>Parkinson disease</term>
<term>Parkinson's disease</term>
<term>Supranuclear Palsy, Progressive (complications)</term>
<term>Supranuclear Palsy, Progressive (drug therapy)</term>
<term>Supranuclear Palsy, Progressive (physiopathology)</term>
<term>Tilt-Table Test</term>
<term>ambulatory blood pressure</term>
<term>autonomic dysfunction</term>
<term>multiple system atrophy</term>
<term>progressive supranuclear palsy</term>
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<term>Multiple System Atrophy</term>
<term>Parkinson Disease</term>
<term>Supranuclear Palsy, Progressive</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Multiple System Atrophy</term>
<term>Parkinson Disease</term>
<term>Supranuclear Palsy, Progressive</term>
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<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Blood Pressure</term>
<term>Circadian Rhythm</term>
<term>Heart Rate</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Autonomic Nervous System</term>
<term>Autonomic Nervous System Diseases</term>
<term>Basal Ganglia Diseases</term>
<term>Hypertension</term>
<term>Multiple System Atrophy</term>
<term>Parkinson Disease</term>
<term>Supranuclear Palsy, Progressive</term>
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<term>Blood Pressure Monitoring, Ambulatory</term>
<term>Cross-Sectional Studies</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
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<term>Atrophie multisystématisée</term>
<term>Maladie de Parkinson</term>
<term>Pathologie du système nerveux</term>
<term>Perte sanguine</term>
<term>Pression artérielle</term>
<term>Pression sanguine</term>
<term>Syndrome extrapyramidal</term>
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<front><div type="abstract" xml:lang="en">Cardiovascular autonomic dysfunction has frequently been reported in some patients with extrapyramidal syndromes, especially multiple system atrophy (MSA) but also Parkinson's disease (PD). However, there are only few reports on the prevalence of cardiovascular autonomic dysfunction progressive in supranuclear palsy (PSP). Moreover, the relation of detailed cardiovascular testing and easy to assess 24‐hour ambulatory blood pressure (BP) is not known. Our study evaluates 24‐hour ambulatory BP monitoring in patients with PD, PSP, MSA, and corresponding controls (Con) and relates the findings to the results of comprehensive cardiovascular autonomic testing. Twenty‐three patients with PD, 25 patients with PSP, 25 patients with MSA, and 26 corresponding controls were studied by 24‐hour ambulatory BP monitoring (ABPM) in comparison to cardiovascular autonomic testing. Patients with PD, PSP, and MSA presented frequently with a pathological nocturnal BP regulation (no decrease or even an increase of nocturnal BP) in comparison to the control group (PD 48%, PSP 40%, MSA 68% vs. Con 8%). In MSA and PD patients, the frequent pathological BP increase during night was closely correlated to orthostatic hypotension. Since loss of nocturnal BP fall is frequent in patients with extrapyramidal syndromes, even if they are free of subjective autonomic dysfunction, we recommend 24‐hour ABPM as an easy to perform screening test, especially if detailed autonomic testing is not available. Pathological loss of nocturnal BP fall may account for increased cardiovascular mortality in extrapyramidal syndromes. © 2009 Movement Disorder Society</div>
</front>
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<tree><country name="Allemagne"><region name="Saxe (Land)"><name sortKey="Schmidt, Claudia" sort="Schmidt, Claudia" uniqKey="Schmidt C" first="Claudia" last="Schmidt">Claudia Schmidt</name>
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<name sortKey="Schweitzer, Katherine" sort="Schweitzer, Katherine" uniqKey="Schweitzer K" first="Katherine" last="Schweitzer">Katherine Schweitzer</name>
<name sortKey="Ziemssen, Tjalf" sort="Ziemssen, Tjalf" uniqKey="Ziemssen T" first="Tjalf" last="Ziemssen">Tjalf Ziemssen</name>
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