MovDisordV3, Main, Exploration, bibRecord, 006433

Reduced glutamate decarboxylase activity in the subthalamic nucleus in patients with tardive dyskinesia

Identifieur interne : 006433 ( Main/Exploration ); précédent : 006432; suivant : 006434

Reduced glutamate decarboxylase activity in the subthalamic nucleus in patients with tardive dyskinesia

Auteurs : Ulf Andersson [Suède] ; Jan-Erik H Gström [Suède] ; Edward D. Levin [Suède] ; Ulf Bondesson [Suède] ; Milan Valverius [Suède] ; Gunne [Suède]

Source :

Movement Disorders [ 0885-3185 ] ; 1989.

RBID : ISTEX:25561A2AC0CEB58D09F4AF6C2A5E32DBE7B29EAD

Descripteurs français

Pascal (Inist)
- Activité enzymatique, Dyskinésie, GABA, Glutamate decarboxylase, Homme, Mouvement involontaire, Neuroleptique, Noyau sousthalamique, Psychotrope, Système nerveux pathologie, Toxicité.
Wicri :
- topic : Homme.

English descriptors

KwdEn :
- Aged, Aged, 80 and over, Death, Sudden (pathology), Dyskinesia, Dyskinesia, Drug-Induced (pathology), Enzymatic activity, Female, GABA, GAD‐activity, Glutamate Decarboxylase (deficiency), Glutamate decarboxylase, Human, Humans, Involuntary movement, Male, Middle Aged, Myocardial Infarction (pathology), Nervous system diseases, Neuroleptic, Psychotropic, Subthalamic nucleus, Tardive dyskinesia, Thalamic Nuclei (pathology), Toxicity.
MESH :
- chemical , deficiency : Glutamate Decarboxylase.
- pathology : Death, Sudden, Dyskinesia, Drug-Induced, Myocardial Infarction, Thalamic Nuclei.
- Aged, Aged, 80 and over, Female, Humans, Male, Middle Aged.

Abstract

Glutamate decarboxylase (GAD) activity was measured in the nuclei of the basal ganglia in patients with neuroleptic‐induced tardive dyskinesia (TD) and controls matched for age and premortem state. In five TD patients, who all had a sudden death, a significant decrease in GAD activity was found in the subthalamic nucleus (STN). The lowered GAD activity in the STN may represent a biochemical substrate for neuroleptic‐induced TD.

Url:

https://api.istex.fr/document/25561A2AC0CEB58D09F4AF6C2A5E32DBE7B29EAD/fulltext/pdf

DOI: 10.1002/mds.870040107

Affiliations:

Le document en format XML

<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Reduced glutamate decarboxylase activity in the subthalamic nucleus in patients with tardive dyskinesia</title>
<author><name sortKey="Andersson, Ulf" sort="Andersson, Ulf" uniqKey="Andersson U" first="Ulf" last="Andersson">Ulf Andersson</name>
</author>
<author><name sortKey="H Gstrom, Jan Rik" sort="H Gstrom, Jan Rik" uniqKey="H Gstrom J" first="Jan-Erik" last="H Gström">Jan-Erik H Gström</name>
</author>
<author><name sortKey="Levin, Edward D" sort="Levin, Edward D" uniqKey="Levin E" first="Edward D." last="Levin">Edward D. Levin</name>
</author>
<author><name sortKey="Bondesson, Ulf" sort="Bondesson, Ulf" uniqKey="Bondesson U" first="Ulf" last="Bondesson">Ulf Bondesson</name>
</author>
<author><name sortKey="Valverius, Milan" sort="Valverius, Milan" uniqKey="Valverius M" first="Milan" last="Valverius">Milan Valverius</name>
</author>
<author><name sortKey="Gunne" sort="Gunne" uniqKey="Gunne" last="Gunne">Gunne</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:25561A2AC0CEB58D09F4AF6C2A5E32DBE7B29EAD</idno>
<date when="1989" year="1989">1989</date>
<idno type="doi">10.1002/mds.870040107</idno>
<idno type="url">https://api.istex.fr/document/25561A2AC0CEB58D09F4AF6C2A5E32DBE7B29EAD/fulltext/pdf</idno>
<idno type="wicri:Area/Istex/Corpus">002F19</idno>
<idno type="wicri:Area/Istex/Curation">002F19</idno>
<idno type="wicri:Area/Istex/Checkpoint">004463</idno>
<idno type="wicri:doubleKey">0885-3185:1989:Andersson U:reduced:glutamate:decarboxylase</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:2927401</idno>
<idno type="wicri:Area/PubMed/Corpus">004F52</idno>
<idno type="wicri:Area/PubMed/Curation">004F52</idno>
<idno type="wicri:Area/PubMed/Checkpoint">004F66</idno>
<idno type="wicri:Area/Ncbi/Merge">004570</idno>
<idno type="wicri:Area/Ncbi/Curation">004570</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">004570</idno>
<idno type="wicri:doubleKey">0885-3185:1989:Andersson U:reduced:glutamate:decarboxylase</idno>
<idno type="wicri:Area/Main/Merge">009786</idno>
<idno type="wicri:source">INIST</idno>
<idno type="RBID">Pascal:90-0194308</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">003978</idno>
<idno type="wicri:Area/PascalFrancis/Curation">002E47</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">003991</idno>
<idno type="wicri:doubleKey">0885-3185:1989:Andersson U:reduced:glutamate:decarboxylase</idno>
<idno type="wicri:Area/Main/Merge">009853</idno>
<idno type="wicri:Area/Main/Curation">006433</idno>
<idno type="wicri:Area/Main/Exploration">006433</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Reduced glutamate decarboxylase activity in the subthalamic nucleus in patients with tardive dyskinesia</title>
<author><name sortKey="Andersson, Ulf" sort="Andersson, Ulf" uniqKey="Andersson U" first="Ulf" last="Andersson">Ulf Andersson</name>
<affiliation wicri:level="1"><country xml:lang="fr">Suède</country>
<wicri:regionArea>Psychiatric Research Center, Ulleråker Hospital, S‐750 17 Uppsala</wicri:regionArea>
<wicri:noRegion>S‐750 17 Uppsala</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="H Gstrom, Jan Rik" sort="H Gstrom, Jan Rik" uniqKey="H Gstrom J" first="Jan-Erik" last="H Gström">Jan-Erik H Gström</name>
<affiliation wicri:level="1"><country xml:lang="fr">Suède</country>
<wicri:regionArea>Psychiatric Research Center, Ulleråker Hospital, S‐750 17 Uppsala</wicri:regionArea>
<wicri:noRegion>S‐750 17 Uppsala</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Levin, Edward D" sort="Levin, Edward D" uniqKey="Levin E" first="Edward D." last="Levin">Edward D. Levin</name>
<affiliation wicri:level="1"><country xml:lang="fr">Suède</country>
<wicri:regionArea>Psychiatric Research Center, Ulleråker Hospital, S‐750 17 Uppsala</wicri:regionArea>
<wicri:noRegion>S‐750 17 Uppsala</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Bondesson, Ulf" sort="Bondesson, Ulf" uniqKey="Bondesson U" first="Ulf" last="Bondesson">Ulf Bondesson</name>
<affiliation wicri:level="1"><country xml:lang="fr">Suède</country>
<wicri:regionArea>Psychiatric Research Center, Ulleråker Hospital, S‐750 17 Uppsala</wicri:regionArea>
<wicri:noRegion>S‐750 17 Uppsala</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Valverius, Milan" sort="Valverius, Milan" uniqKey="Valverius M" first="Milan" last="Valverius">Milan Valverius</name>
<affiliation wicri:level="3"><country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Forensic Medicine, Karolinska Institute, Stockholm</wicri:regionArea>
<placeName><settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gunne" sort="Gunne" uniqKey="Gunne" last="Gunne">Gunne</name>
<affiliation wicri:level="1"><country xml:lang="fr">Suède</country>
<wicri:regionArea>Psychiatric Research Center, Ulleråker Hospital, S‐750 17 Uppsala</wicri:regionArea>
<wicri:noRegion>S‐750 17 Uppsala</wicri:noRegion>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Movement Disorders</title>
<title level="j" type="sub">Official Journal of the Movement Disorder Society</title>
<title level="j" type="abbrev">Mov. Disord.</title>
<idno type="ISSN">0885-3185</idno>
<idno type="eISSN">1531-8257</idno>
<imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher>
<pubPlace>Hoboken</pubPlace>
<date type="published" when="1989">1989</date>
<biblScope unit="vol">4</biblScope>
<biblScope unit="issue">1</biblScope>
<biblScope unit="page" from="37">37</biblScope>
<biblScope unit="page" to="46">46</biblScope>
</imprint>
<idno type="ISSN">0885-3185</idno>
</series>
<idno type="istex">25561A2AC0CEB58D09F4AF6C2A5E32DBE7B29EAD</idno>
<idno type="DOI">10.1002/mds.870040107</idno>
<idno type="ArticleID">MDS870040107</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term>
<term>Aged, 80 and over</term>
<term>Death, Sudden (pathology)</term>
<term>Dyskinesia</term>
<term>Dyskinesia, Drug-Induced (pathology)</term>
<term>Enzymatic activity</term>
<term>Female</term>
<term>GABA</term>
<term>GAD‐activity</term>
<term>Glutamate Decarboxylase (deficiency)</term>
<term>Glutamate decarboxylase</term>
<term>Human</term>
<term>Humans</term>
<term>Involuntary movement</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Myocardial Infarction (pathology)</term>
<term>Nervous system diseases</term>
<term>Neuroleptic</term>
<term>Psychotropic</term>
<term>Subthalamic nucleus</term>
<term>Tardive dyskinesia</term>
<term>Thalamic Nuclei (pathology)</term>
<term>Toxicity</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="deficiency" xml:lang="en"><term>Glutamate Decarboxylase</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Death, Sudden</term>
<term>Dyskinesia, Drug-Induced</term>
<term>Myocardial Infarction</term>
<term>Thalamic Nuclei</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Aged, 80 and over</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Activité enzymatique</term>
<term>Dyskinésie</term>
<term>GABA</term>
<term>Glutamate decarboxylase</term>
<term>Homme</term>
<term>Mouvement involontaire</term>
<term>Neuroleptique</term>
<term>Noyau sousthalamique</term>
<term>Psychotrope</term>
<term>Système nerveux pathologie</term>
<term>Toxicité</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Glutamate decarboxylase (GAD) activity was measured in the nuclei of the basal ganglia in patients with neuroleptic‐induced tardive dyskinesia (TD) and controls matched for age and premortem state. In five TD patients, who all had a sudden death, a significant decrease in GAD activity was found in the subthalamic nucleus (STN). The lowered GAD activity in the STN may represent a biochemical substrate for neuroleptic‐induced TD.</div>
</front>
</TEI>
<affiliations><list><country><li>Suède</li>
</country>
<region><li>Svealand</li>
</region>
<settlement><li>Stockholm</li>
</settlement>
</list>
<tree><country name="Suède"><noRegion><name sortKey="Andersson, Ulf" sort="Andersson, Ulf" uniqKey="Andersson U" first="Ulf" last="Andersson">Ulf Andersson</name>
</noRegion>
<name sortKey="Bondesson, Ulf" sort="Bondesson, Ulf" uniqKey="Bondesson U" first="Ulf" last="Bondesson">Ulf Bondesson</name>
<name sortKey="Gunne" sort="Gunne" uniqKey="Gunne" last="Gunne">Gunne</name>
<name sortKey="H Gstrom, Jan Rik" sort="H Gstrom, Jan Rik" uniqKey="H Gstrom J" first="Jan-Erik" last="H Gström">Jan-Erik H Gström</name>
<name sortKey="Levin, Edward D" sort="Levin, Edward D" uniqKey="Levin E" first="Edward D." last="Levin">Edward D. Levin</name>
<name sortKey="Valverius, Milan" sort="Valverius, Milan" uniqKey="Valverius M" first="Milan" last="Valverius">Milan Valverius</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 006433 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 006433 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Santé
   |area=    MovDisordV3
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     ISTEX:25561A2AC0CEB58D09F4AF6C2A5E32DBE7B29EAD
   |texte=   Reduced glutamate decarboxylase activity in the subthalamic nucleus in patients with tardive dyskinesia
}}

This area was generated with Dilib version V0.6.23.
Data generation: Sun Jul 3 12:29:32 2016. Site generation: Wed Feb 14 10:52:30 2024

Movement Disorders (revue)

Reduced glutamate decarboxylase activity in the subthalamic nucleus in patients with tardive dyskinesia

Reduced glutamate decarboxylase activity in the subthalamic nucleus in patients with tardive dyskinesia

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

	Movement Disorders (revue)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.