A new tremor mutant in the pietrain pig: An animal model of orthostatic tremor? Clinical and neurophysiological observations
Identifieur interne : 005424 ( Main/Exploration ); précédent : 005423; suivant : 005425A new tremor mutant in the pietrain pig: An animal model of orthostatic tremor? Clinical and neurophysiological observations
Auteurs : Jörg Wissel [Autriche] ; Barbara Harlizuis ; Angelica Richter ; Wolfgang Löscher ; Ludwig Schelosky [Allemagne] ; Udo Scholz [Allemagne] ; Werner Poewe [Autriche]Source :
- Movement Disorders [ 0885-3185 ] ; 1997-09.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- Animal, Animal model, Animal models, Animals, Animals, Inbred Strains, Campus syndrome, Case-Control Studies, Clinical form, Creep syndrome, Disease Models, Animal, Electromyography, Extremities (physiopathology), Gait (physiology), Humans, Muscle, Skeletal (physiopathology), Neural Conduction, Observation, Orthostatic tremor, Oscillometry, Pig, Porcine tremor, Posture (physiology), Swine, Tremor, Tremor (genetics), Tremor (physiopathology), Ulnar Nerve (physiopathology), Videotape Recording.
- MESH :
- genetics : Tremor.
- physiology : Gait, Posture.
- physiopathology : Extremities, Muscle, Skeletal, Tremor, Ulnar Nerve.
- Animals, Animals, Inbred Strains, Case-Control Studies, Disease Models, Animal, Electromyography, Humans, Neural Conduction, Observation, Oscillometry, Swine, Videotape Recording.
Abstract
A new tremor mutant, the “Campus syndrome” was studied in a breed of Pietrain pigs. Affected pigs showed a coarse tremor of the extremities when standing and walking, so they tended to remain recumbent, during which the tremor was suppressed. Needle electromyographic recordings of the semitendinosus muscle plus accelerometry revealed a high‐amplitude 14‐ to 15‐Hz tremor pattern activated specifically upon standing but maintained during walking. The observed syndrome thus bears similarities to the human condition of orthostatic tremor and might serve as an animal model for this as yet poorly understood disorder.
Url:
DOI: 10.1002/mds.870120519
Affiliations:
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Le document en format XML
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<term>Campus syndrome</term>
<term>Case-Control Studies</term>
<term>Clinical form</term>
<term>Creep syndrome</term>
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<term>Electromyography</term>
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<term>Humans</term>
<term>Muscle, Skeletal (physiopathology)</term>
<term>Neural Conduction</term>
<term>Observation</term>
<term>Orthostatic tremor</term>
<term>Oscillometry</term>
<term>Pig</term>
<term>Porcine tremor</term>
<term>Posture (physiology)</term>
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<term>Tremor</term>
<term>Tremor (genetics)</term>
<term>Tremor (physiopathology)</term>
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<term>Videotape Recording</term>
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<term>Tremor</term>
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<term>Case-Control Studies</term>
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<term>Electromyography</term>
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<term>Neural Conduction</term>
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<term>Swine</term>
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<front><div type="abstract" xml:lang="en">A new tremor mutant, the “Campus syndrome” was studied in a breed of Pietrain pigs. Affected pigs showed a coarse tremor of the extremities when standing and walking, so they tended to remain recumbent, during which the tremor was suppressed. Needle electromyographic recordings of the semitendinosus muscle plus accelerometry revealed a high‐amplitude 14‐ to 15‐Hz tremor pattern activated specifically upon standing but maintained during walking. The observed syndrome thus bears similarities to the human condition of orthostatic tremor and might serve as an animal model for this as yet poorly understood disorder.</div>
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