MovDisordV3, Main, Exploration, bibRecord, 003F37

Significance of non‐presynaptic SPECT tracer methods in Parkinson's disease

Identifieur interne : 003F37 ( Main/Exploration ); précédent : 003F36; suivant : 003F38

Significance of non‐presynaptic SPECT tracer methods in Parkinson's disease

Auteurs : Klaus L. Leenders [Pays-Bas]

Source :

Movement Disorders [ 0885-3185 ] ; 2003-10.

RBID : ISTEX:53B064B1181BC56EAFB11CDCE377DC7BE4C5B045

Descripteurs français

Pascal (Inist)
- Diagnostic, Débit sanguin régional, HMPAO, Homme, IBZM, Indication, Parkinson maladie, Produit diagnostic, Radioisotope, Récepteur dopaminergique D2, Technique, Tomographie émission positon, Tomoscintigraphie émission monophotonique.
Wicri :
- topic : Homme.

English descriptors

KwdEn :
- Benzamides (diagnostic use), Brain (blood supply), Brain (radionuclide imaging), Corpus Striatum (radionuclide imaging), D2 Dopamine receptor, Diagnosis, Diagnosis, Differential, Diagnostic agent, HMPAO, Human, Humans, IBZM, Indication, PET, Parkinson Disease (radionuclide imaging), Parkinson disease, Parkinson's disease, Positron emission tomography, Pyrrolidines (diagnostic use), Radioisotope, Receptors, Dopamine D2 (analysis), Receptors, Presynaptic (analysis), Regional Blood Flow (physiology), Regional blood flow, SPECT, Sensitivity and Specificity, Single photon emission tomography, Technetium Tc 99m Exametazime (diagnostic use), Technique, Tomography, Emission-Computed, Tomography, Emission-Computed, Single-Photon.
MESH :
- chemical , analysis : Receptors, Dopamine D2, Receptors, Presynaptic.
- chemical , diagnostic use : Benzamides, Pyrrolidines, Technetium Tc 99m Exametazime.
- blood supply : Brain.
- physiology : Regional Blood Flow.
- radionuclide imaging : Brain, Corpus Striatum, Parkinson Disease.
- Diagnosis, Differential, Humans, Sensitivity and Specificity, Tomography, Emission-Computed, Tomography, Emission-Computed, Single-Photon.

Abstract

Tropane‐related tracers for SPECT and PET scanning have shown their value in assessing the in vivo striatal presynaptic status of the dopaminergic neurotransmitter system in man. Previously, there were a few other tracers suggested to be useful in the study of in vivo brain biochemistry in humans, particularly in patients afflicted with Parkinson's disease (PD) or parkinsonian syndromes. We summarize the work concerning the two main tracers applied in that context using single photon emission tomography (SPECT) scanning in patients with PD: IBZM and HMPAO. IBZM binds specifically to striatal dopamine D2 receptors and HMPAO uptake is a measure of cerebral tissue perfusion. © 2003 Movement Disorder Society

Url:

https://api.istex.fr/document/53B064B1181BC56EAFB11CDCE377DC7BE4C5B045/fulltext/pdf

DOI: 10.1002/mds.10577

Affiliations:

Le document en format XML

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<term>D2 Dopamine receptor</term>
<term>Diagnosis</term>
<term>Diagnosis, Differential</term>
<term>Diagnostic agent</term>
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<term>Humans</term>
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<term>Indication</term>
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<term>Parkinson Disease</term>
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<term>Sensitivity and Specificity</term>
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<term>Tomography, Emission-Computed, Single-Photon</term>
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<term>Indication</term>
<term>Parkinson maladie</term>
<term>Produit diagnostic</term>
<term>Radioisotope</term>
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<term>Technique</term>
<term>Tomographie émission positon</term>
<term>Tomoscintigraphie émission monophotonique</term>
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<front><div type="abstract" xml:lang="en">Tropane‐related tracers for SPECT and PET scanning have shown their value in assessing the in vivo striatal presynaptic status of the dopaminergic neurotransmitter system in man. Previously, there were a few other tracers suggested to be useful in the study of in vivo brain biochemistry in humans, particularly in patients afflicted with Parkinson's disease (PD) or parkinsonian syndromes. We summarize the work concerning the two main tracers applied in that context using single photon emission tomography (SPECT) scanning in patients with PD: IBZM and HMPAO. IBZM binds specifically to striatal dopamine D2 receptors and HMPAO uptake is a measure of cerebral tissue perfusion. © 2003 Movement Disorder Society</div>
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Movement Disorders (revue)

Significance of non‐presynaptic SPECT tracer methods in Parkinson's disease

Significance of non‐presynaptic SPECT tracer methods in Parkinson's disease

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

	Movement Disorders (revue)
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