MovDisordV3, Main, Curation, bibRecord, 004F76

Inhibition of levodopa effects by internal pallidal stimulation

Identifieur interne : 004F76 ( Main/Curation ); précédent : 004F75; suivant : 004F77

Inhibition of levodopa effects by internal pallidal stimulation

Auteurs : Paul Krack [France] ; Pierre Pollak [France] ; Patricia Limousin [France] ; Dominique Hoffmann [France] ; Abdelhamid Benazzouz [France] ; Alim-Louis Benabid [France]

Source :

Movement Disorders [ 0885-3185 ] ; 1998-07.

RBID : ISTEX:A3E18445A389F4FC66F38749E041592C1C5AE95A

Descripteurs français

Pascal (Inist)
- Adulte, Antiparkinsonien, Chimiothérapie, Dyskinésie, Effet on, Etude cas, Haute fréquence, Indication, Interne, Lévodopa, Motricité, Mâle, Pallidum, Parkinson maladie, Stimulus électrique, Toxicité, Traitement instrumental.
Wicri :
- topic : Adulte.

English descriptors

KwdEn :
- Adult, Antiparkinson Agents (administration & dosage), Antiparkinson Agents (adverse effects), Antiparkinson agent, Case study, Chemotherapy, Combined Modality Therapy, Dominance, Cerebral (drug effects), Dominance, Cerebral (physiology), Dyskinesia, Dyskinesia, Drug-Induced (diagnosis), Dyskinesia, Drug-Induced (physiopathology), Dyskinesia, Drug-Induced (therapy), Electric Stimulation Therapy, Electrical stimulation, Electrical stimulus, Electrodes, Implanted, Globus Pallidus (drug effects), Globus Pallidus (physiopathology), High frequency, Humans, Indication, Instrumentation therapy, Internal, Internal pallidum, Levodopa, Levodopa (administration & dosage), Levodopa (adverse effects), Male, Middle Aged, Motricity, On effect, Pallidum, Parkinson Disease (physiopathology), Parkinson Disease (therapy), Parkinson disease, Parkinson's disease, Toxicity.
MESH :
- chemical , administration & dosage : Antiparkinson Agents, Levodopa.
- chemical , adverse effects : Antiparkinson Agents, Levodopa.
- diagnosis : Dyskinesia, Drug-Induced.
- drug effects : Dominance, Cerebral, Globus Pallidus.
- physiology : Dominance, Cerebral.
- physiopathology : Dyskinesia, Drug-Induced, Globus Pallidus, Parkinson Disease.
- therapy : Dyskinesia, Drug-Induced, Parkinson Disease.
- Combined Modality Therapy, Electric Stimulation Therapy, Electrodes, Implanted, Humans, Male, Middle Aged.

Abstract

We report three patients with bilateral GPi stimulation for stage 4 Parkinson's disease (PD) with severe levodopa‐induced dyskinesias (LID). In all three it was possible to completely inhibit LID using high‐stimulation parameters. Parallel to complete inhibition of LID, an inhibition of the anti‐akinetic effect of levodopa was observed, whereas, at the same time, rigidity was markedly improved. GPi stimulation is adaptable over time, and stimulation parameters have to be programmed according to off‐and on‐period motor symptoms. The main interest of stimulation is the possibility of finding a compromise between LID alleviation in on‐phase without loss of the beneficial motor effects and improvement in parkinsonism in off‐phase. In some patients, residual dyskinesias have to be accepted so as not to aggravate on‐period motor symptoms by a presumed overinhibition of basal ganglia outflow.

Url:

https://api.istex.fr/document/A3E18445A389F4FC66F38749E041592C1C5AE95A/fulltext/pdf

DOI: 10.1002/mds.870130407

Links toward previous steps (curation, corpus...)

to stream Istex, to step Corpus: Pour aller vers cette notice dans l'étape Curation :002A89
to stream Istex, to step Curation: Pour aller vers cette notice dans l'étape Curation :002A89
to stream Istex, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :003711
to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :004381
to stream PubMed, to step Curation: Pour aller vers cette notice dans l'étape Curation :004381
to stream PubMed, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :004407
to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :005002
to stream Ncbi, to step Curation: Pour aller vers cette notice dans l'étape Curation :005002
to stream Ncbi, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :005002
to stream Main, to step Merge: Pour aller vers cette notice dans l'étape Curation :007E88
to stream PascalFrancis, to step Corpus: Pour aller vers cette notice dans l'étape Curation :002F63
to stream PascalFrancis, to step Curation: Pour aller vers cette notice dans l'étape Curation :003861
to stream PascalFrancis, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :002F89
to stream Main, to step Merge: Pour aller vers cette notice dans l'étape Curation :008113

Links to Exploration step

ISTEX:A3E18445A389F4FC66F38749E041592C1C5AE95A

Le document en format XML

<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Inhibition of levodopa effects by internal pallidal stimulation</title>
<author><name sortKey="Krack, Paul" sort="Krack, Paul" uniqKey="Krack P" first="Paul" last="Krack">Paul Krack</name>
</author>
<author><name sortKey="Pollak, Pierre" sort="Pollak, Pierre" uniqKey="Pollak P" first="Pierre" last="Pollak">Pierre Pollak</name>
<affiliation><country>France</country>
<placeName><settlement type="city">Grenoble</settlement>
<region type="region" nuts="2">Auvergne-Rhône-Alpes</region>
<region type="old region" nuts="2">Rhône-Alpes</region>
</placeName>
<orgName type="hospital" n="4">Centre hospitalier universitaire Grenoble Alpes</orgName>
</affiliation>
</author>
<author><name sortKey="Limousin, Patricia" sort="Limousin, Patricia" uniqKey="Limousin P" first="Patricia" last="Limousin">Patricia Limousin</name>
</author>
<author><name sortKey="Hoffmann, Dominique" sort="Hoffmann, Dominique" uniqKey="Hoffmann D" first="Dominique" last="Hoffmann">Dominique Hoffmann</name>
</author>
<author><name sortKey="Benazzouz, Abdelhamid" sort="Benazzouz, Abdelhamid" uniqKey="Benazzouz A" first="Abdelhamid" last="Benazzouz">Abdelhamid Benazzouz</name>
</author>
<author><name sortKey="Benabid, Alim Ouis" sort="Benabid, Alim Ouis" uniqKey="Benabid A" first="Alim-Louis" last="Benabid">Alim-Louis Benabid</name>
<affiliation><country>France</country>
<placeName><settlement type="city">Grenoble</settlement>
<region type="region" nuts="2">Auvergne-Rhône-Alpes</region>
<region type="old region" nuts="2">Rhône-Alpes</region>
</placeName>
<orgName type="hospital" n="4">Centre hospitalier universitaire Grenoble Alpes</orgName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:A3E18445A389F4FC66F38749E041592C1C5AE95A</idno>
<date when="1998" year="1998">1998</date>
<idno type="doi">10.1002/mds.870130407</idno>
<idno type="url">https://api.istex.fr/document/A3E18445A389F4FC66F38749E041592C1C5AE95A/fulltext/pdf</idno>
<idno type="wicri:Area/Istex/Corpus">002A89</idno>
<idno type="wicri:Area/Istex/Curation">002A89</idno>
<idno type="wicri:Area/Istex/Checkpoint">003711</idno>
<idno type="wicri:doubleKey">0885-3185:1998:Krack P:inhibition:of:levodopa</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:9686769</idno>
<idno type="wicri:Area/PubMed/Corpus">004381</idno>
<idno type="wicri:Area/PubMed/Curation">004381</idno>
<idno type="wicri:Area/PubMed/Checkpoint">004407</idno>
<idno type="wicri:Area/Ncbi/Merge">005002</idno>
<idno type="wicri:Area/Ncbi/Curation">005002</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">005002</idno>
<idno type="wicri:doubleKey">0885-3185:1998:Krack P:inhibition:of:levodopa</idno>
<idno type="wicri:Area/Main/Merge">007E88</idno>
<idno type="wicri:source">INIST</idno>
<idno type="RBID">Pascal:98-0354368</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">002F63</idno>
<idno type="wicri:Area/PascalFrancis/Curation">003861</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">002F89</idno>
<idno type="wicri:doubleKey">0885-3185:1998:Krack P:inhibition:of:levodopa</idno>
<idno type="wicri:Area/Main/Merge">008113</idno>
<idno type="wicri:Area/Main/Curation">004F76</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Inhibition of levodopa effects by internal pallidal stimulation</title>
<author><name sortKey="Krack, Paul" sort="Krack, Paul" uniqKey="Krack P" first="Paul" last="Krack">Paul Krack</name>
<affiliation wicri:level="1"><country xml:lang="fr">France</country>
<wicri:regionArea>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</wicri:regionArea>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Pollak, Pierre" sort="Pollak, Pierre" uniqKey="Pollak P" first="Pierre" last="Pollak">Pierre Pollak</name>
<affiliation wicri:level="1"><country xml:lang="fr">France</country>
<wicri:regionArea>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</wicri:regionArea>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
<placeName><settlement type="city">Grenoble</settlement>
<region type="region" nuts="2">Auvergne-Rhône-Alpes</region>
<region type="old region" nuts="2">Rhône-Alpes</region>
</placeName>
<orgName type="hospital" n="4">Centre hospitalier universitaire Grenoble Alpes</orgName>
</affiliation>
</author>
<author><name sortKey="Limousin, Patricia" sort="Limousin, Patricia" uniqKey="Limousin P" first="Patricia" last="Limousin">Patricia Limousin</name>
<affiliation wicri:level="1"><country xml:lang="fr">France</country>
<wicri:regionArea>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</wicri:regionArea>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hoffmann, Dominique" sort="Hoffmann, Dominique" uniqKey="Hoffmann D" first="Dominique" last="Hoffmann">Dominique Hoffmann</name>
<affiliation wicri:level="1"><country xml:lang="fr">France</country>
<wicri:regionArea>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</wicri:regionArea>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Benazzouz, Abdelhamid" sort="Benazzouz, Abdelhamid" uniqKey="Benazzouz A" first="Abdelhamid" last="Benazzouz">Abdelhamid Benazzouz</name>
<affiliation wicri:level="1"><country xml:lang="fr">France</country>
<wicri:regionArea>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</wicri:regionArea>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Benabid, Alim Ouis" sort="Benabid, Alim Ouis" uniqKey="Benabid A" first="Alim-Louis" last="Benabid">Alim-Louis Benabid</name>
<affiliation wicri:level="1"><country xml:lang="fr">France</country>
<wicri:regionArea>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</wicri:regionArea>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
<placeName><settlement type="city">Grenoble</settlement>
<region type="region" nuts="2">Auvergne-Rhône-Alpes</region>
<region type="old region" nuts="2">Rhône-Alpes</region>
</placeName>
<orgName type="hospital" n="4">Centre hospitalier universitaire Grenoble Alpes</orgName>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Movement Disorders</title>
<title level="j" type="sub">Official Journal of the Movement Disorder Society</title>
<title level="j" type="abbrev">Mov. Disord.</title>
<idno type="ISSN">0885-3185</idno>
<idno type="eISSN">1531-8257</idno>
<imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher>
<pubPlace>Hoboken</pubPlace>
<date type="published" when="1998-07">1998-07</date>
<biblScope unit="vol">13</biblScope>
<biblScope unit="issue">4</biblScope>
<biblScope unit="page" from="648">648</biblScope>
<biblScope unit="page" to="652">652</biblScope>
</imprint>
<idno type="ISSN">0885-3185</idno>
</series>
<idno type="istex">A3E18445A389F4FC66F38749E041592C1C5AE95A</idno>
<idno type="DOI">10.1002/mds.870130407</idno>
<idno type="ArticleID">MDS870130407</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Antiparkinson Agents (administration & dosage)</term>
<term>Antiparkinson Agents (adverse effects)</term>
<term>Antiparkinson agent</term>
<term>Case study</term>
<term>Chemotherapy</term>
<term>Combined Modality Therapy</term>
<term>Dominance, Cerebral (drug effects)</term>
<term>Dominance, Cerebral (physiology)</term>
<term>Dyskinesia</term>
<term>Dyskinesia, Drug-Induced (diagnosis)</term>
<term>Dyskinesia, Drug-Induced (physiopathology)</term>
<term>Dyskinesia, Drug-Induced (therapy)</term>
<term>Electric Stimulation Therapy</term>
<term>Electrical stimulation</term>
<term>Electrical stimulus</term>
<term>Electrodes, Implanted</term>
<term>Globus Pallidus (drug effects)</term>
<term>Globus Pallidus (physiopathology)</term>
<term>High frequency</term>
<term>Humans</term>
<term>Indication</term>
<term>Instrumentation therapy</term>
<term>Internal</term>
<term>Internal pallidum</term>
<term>Levodopa</term>
<term>Levodopa (administration & dosage)</term>
<term>Levodopa (adverse effects)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Motricity</term>
<term>On effect</term>
<term>Pallidum</term>
<term>Parkinson Disease (physiopathology)</term>
<term>Parkinson Disease (therapy)</term>
<term>Parkinson disease</term>
<term>Parkinson's disease</term>
<term>Toxicity</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Antiparkinson Agents</term>
<term>Levodopa</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Antiparkinson Agents</term>
<term>Levodopa</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Dyskinesia, Drug-Induced</term>
</keywords>
<keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Dominance, Cerebral</term>
<term>Globus Pallidus</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Dominance, Cerebral</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Dyskinesia, Drug-Induced</term>
<term>Globus Pallidus</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Dyskinesia, Drug-Induced</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Combined Modality Therapy</term>
<term>Electric Stimulation Therapy</term>
<term>Electrodes, Implanted</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Adulte</term>
<term>Antiparkinsonien</term>
<term>Chimiothérapie</term>
<term>Dyskinésie</term>
<term>Effet on</term>
<term>Etude cas</term>
<term>Haute fréquence</term>
<term>Indication</term>
<term>Interne</term>
<term>Lévodopa</term>
<term>Motricité</term>
<term>Mâle</term>
<term>Pallidum</term>
<term>Parkinson maladie</term>
<term>Stimulus électrique</term>
<term>Toxicité</term>
<term>Traitement instrumental</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Adulte</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">We report three patients with bilateral GPi stimulation for stage 4 Parkinson's disease (PD) with severe levodopa‐induced dyskinesias (LID). In all three it was possible to completely inhibit LID using high‐stimulation parameters. Parallel to complete inhibition of LID, an inhibition of the anti‐akinetic effect of levodopa was observed, whereas, at the same time, rigidity was markedly improved. GPi stimulation is adaptable over time, and stimulation parameters have to be programmed according to off‐and on‐period motor symptoms. The main interest of stimulation is the possibility of finding a compromise between LID alleviation in on‐phase without loss of the beneficial motor effects and improvement in parkinsonism in off‐phase. In some patients, residual dyskinesias have to be accepted so as not to aggravate on‐period motor symptoms by a presumed overinhibition of basal ganglia outflow.</div>
</front>
</TEI>
<double idat="0885-3185:1998:Krack P:inhibition:of:levodopa"><INIST><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Inhibition of levodopa effects by internal pallidal stimulation</title>
<author><name sortKey="Krack, P" sort="Krack, P" uniqKey="Krack P" first="P." last="Krack">P. Krack</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</s1>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>France</country>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
<wicri:noRegion>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Pollak, P" sort="Pollak, P" uniqKey="Pollak P" first="P." last="Pollak">Pierre Pollak</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</s1>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>France</country>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
<wicri:noRegion>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</wicri:noRegion>
<placeName><settlement type="city">Grenoble</settlement>
<region type="region" nuts="2">Auvergne-Rhône-Alpes</region>
<region type="old region" nuts="2">Rhône-Alpes</region>
</placeName>
<orgName type="hospital" n="4">Centre hospitalier universitaire Grenoble Alpes</orgName>
</affiliation>
</author>
<author><name sortKey="Limousin, P" sort="Limousin, P" uniqKey="Limousin P" first="P." last="Limousin">P. Limousin</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</s1>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>France</country>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
<wicri:noRegion>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hoffmann, D" sort="Hoffmann, D" uniqKey="Hoffmann D" first="D." last="Hoffmann">D. Hoffmann</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</s1>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>France</country>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
<wicri:noRegion>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Benazzouz, A" sort="Benazzouz, A" uniqKey="Benazzouz A" first="A." last="Benazzouz">A. Benazzouz</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</s1>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>France</country>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
<wicri:noRegion>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Benabid, A L" sort="Benabid, A L" uniqKey="Benabid A" first="A.-L." last="Benabid">Alim-Louis Benabid</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</s1>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>France</country>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
<wicri:noRegion>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</wicri:noRegion>
<placeName><settlement type="city">Grenoble</settlement>
<region type="region" nuts="2">Auvergne-Rhône-Alpes</region>
<region type="old region" nuts="2">Rhône-Alpes</region>
</placeName>
<orgName type="hospital" n="4">Centre hospitalier universitaire Grenoble Alpes</orgName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">98-0354368</idno>
<date when="1998">1998</date>
<idno type="stanalyst">PASCAL 98-0354368 INIST</idno>
<idno type="RBID">Pascal:98-0354368</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">002F63</idno>
<idno type="wicri:Area/PascalFrancis/Curation">003861</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">002F89</idno>
<idno type="wicri:doubleKey">0885-3185:1998:Krack P:inhibition:of:levodopa</idno>
<idno type="wicri:Area/Main/Merge">008113</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Inhibition of levodopa effects by internal pallidal stimulation</title>
<author><name sortKey="Krack, P" sort="Krack, P" uniqKey="Krack P" first="P." last="Krack">P. Krack</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</s1>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>France</country>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
<wicri:noRegion>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Pollak, P" sort="Pollak, P" uniqKey="Pollak P" first="P." last="Pollak">Pierre Pollak</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</s1>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>France</country>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
<wicri:noRegion>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</wicri:noRegion>
<placeName><settlement type="city">Grenoble</settlement>
<region type="region" nuts="2">Auvergne-Rhône-Alpes</region>
<region type="old region" nuts="2">Rhône-Alpes</region>
</placeName>
<orgName type="hospital" n="4">Centre hospitalier universitaire Grenoble Alpes</orgName>
</affiliation>
</author>
<author><name sortKey="Limousin, P" sort="Limousin, P" uniqKey="Limousin P" first="P." last="Limousin">P. Limousin</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</s1>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>France</country>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
<wicri:noRegion>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hoffmann, D" sort="Hoffmann, D" uniqKey="Hoffmann D" first="D." last="Hoffmann">D. Hoffmann</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</s1>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>France</country>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
<wicri:noRegion>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Benazzouz, A" sort="Benazzouz, A" uniqKey="Benazzouz A" first="A." last="Benazzouz">A. Benazzouz</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</s1>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>France</country>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
<wicri:noRegion>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Benabid, A L" sort="Benabid, A L" uniqKey="Benabid A" first="A.-L." last="Benabid">Alim-Louis Benabid</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</s1>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>France</country>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
<wicri:noRegion>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</wicri:noRegion>
<placeName><settlement type="city">Grenoble</settlement>
<region type="region" nuts="2">Auvergne-Rhône-Alpes</region>
<region type="old region" nuts="2">Rhône-Alpes</region>
</placeName>
<orgName type="hospital" n="4">Centre hospitalier universitaire Grenoble Alpes</orgName>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Movement disorders</title>
<title level="j" type="abbreviated">Mov. disord.</title>
<idno type="ISSN">0885-3185</idno>
<imprint><date when="1998">1998</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Movement disorders</title>
<title level="j" type="abbreviated">Mov. disord.</title>
<idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Antiparkinson agent</term>
<term>Case study</term>
<term>Chemotherapy</term>
<term>Dyskinesia</term>
<term>Electrical stimulus</term>
<term>High frequency</term>
<term>Indication</term>
<term>Instrumentation therapy</term>
<term>Internal</term>
<term>Levodopa</term>
<term>Male</term>
<term>Motricity</term>
<term>On effect</term>
<term>Pallidum</term>
<term>Parkinson disease</term>
<term>Toxicity</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Stimulus électrique</term>
<term>Pallidum</term>
<term>Haute fréquence</term>
<term>Parkinson maladie</term>
<term>Lévodopa</term>
<term>Chimiothérapie</term>
<term>Antiparkinsonien</term>
<term>Dyskinésie</term>
<term>Effet on</term>
<term>Motricité</term>
<term>Interne</term>
<term>Indication</term>
<term>Traitement instrumental</term>
<term>Toxicité</term>
<term>Etude cas</term>
<term>Adulte</term>
<term>Mâle</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Adulte</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
</TEI>
</INIST>
<ISTEX><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Inhibition of levodopa effects by internal pallidal stimulation</title>
<author><name sortKey="Krack, Paul" sort="Krack, Paul" uniqKey="Krack P" first="Paul" last="Krack">Paul Krack</name>
</author>
<author><name sortKey="Pollak, Pierre" sort="Pollak, Pierre" uniqKey="Pollak P" first="Pierre" last="Pollak">Pierre Pollak</name>
<affiliation><country>France</country>
<placeName><settlement type="city">Grenoble</settlement>
<region type="region" nuts="2">Auvergne-Rhône-Alpes</region>
<region type="old region" nuts="2">Rhône-Alpes</region>
</placeName>
<orgName type="hospital" n="4">Centre hospitalier universitaire Grenoble Alpes</orgName>
</affiliation>
</author>
<author><name sortKey="Limousin, Patricia" sort="Limousin, Patricia" uniqKey="Limousin P" first="Patricia" last="Limousin">Patricia Limousin</name>
</author>
<author><name sortKey="Hoffmann, Dominique" sort="Hoffmann, Dominique" uniqKey="Hoffmann D" first="Dominique" last="Hoffmann">Dominique Hoffmann</name>
</author>
<author><name sortKey="Benazzouz, Abdelhamid" sort="Benazzouz, Abdelhamid" uniqKey="Benazzouz A" first="Abdelhamid" last="Benazzouz">Abdelhamid Benazzouz</name>
</author>
<author><name sortKey="Benabid, Alim Ouis" sort="Benabid, Alim Ouis" uniqKey="Benabid A" first="Alim-Louis" last="Benabid">Alim-Louis Benabid</name>
<affiliation><country>France</country>
<placeName><settlement type="city">Grenoble</settlement>
<region type="region" nuts="2">Auvergne-Rhône-Alpes</region>
<region type="old region" nuts="2">Rhône-Alpes</region>
</placeName>
<orgName type="hospital" n="4">Centre hospitalier universitaire Grenoble Alpes</orgName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:A3E18445A389F4FC66F38749E041592C1C5AE95A</idno>
<date when="1998" year="1998">1998</date>
<idno type="doi">10.1002/mds.870130407</idno>
<idno type="url">https://api.istex.fr/document/A3E18445A389F4FC66F38749E041592C1C5AE95A/fulltext/pdf</idno>
<idno type="wicri:Area/Istex/Corpus">002A89</idno>
<idno type="wicri:Area/Istex/Curation">002A89</idno>
<idno type="wicri:Area/Istex/Checkpoint">003711</idno>
<idno type="wicri:doubleKey">0885-3185:1998:Krack P:inhibition:of:levodopa</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:9686769</idno>
<idno type="wicri:Area/PubMed/Corpus">004381</idno>
<idno type="wicri:Area/PubMed/Curation">004381</idno>
<idno type="wicri:Area/PubMed/Checkpoint">004407</idno>
<idno type="wicri:Area/Ncbi/Merge">005002</idno>
<idno type="wicri:Area/Ncbi/Curation">005002</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">005002</idno>
<idno type="wicri:doubleKey">0885-3185:1998:Krack P:inhibition:of:levodopa</idno>
<idno type="wicri:Area/Main/Merge">007E88</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Inhibition of levodopa effects by internal pallidal stimulation</title>
<author><name sortKey="Krack, Paul" sort="Krack, Paul" uniqKey="Krack P" first="Paul" last="Krack">Paul Krack</name>
<affiliation wicri:level="1"><country xml:lang="fr">France</country>
<wicri:regionArea>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</wicri:regionArea>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Pollak, Pierre" sort="Pollak, Pierre" uniqKey="Pollak P" first="Pierre" last="Pollak">Pierre Pollak</name>
<affiliation wicri:level="1"><country xml:lang="fr">France</country>
<wicri:regionArea>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</wicri:regionArea>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
<placeName><settlement type="city">Grenoble</settlement>
<region type="region" nuts="2">Auvergne-Rhône-Alpes</region>
<region type="old region" nuts="2">Rhône-Alpes</region>
</placeName>
<orgName type="hospital" n="4">Centre hospitalier universitaire Grenoble Alpes</orgName>
</affiliation>
</author>
<author><name sortKey="Limousin, Patricia" sort="Limousin, Patricia" uniqKey="Limousin P" first="Patricia" last="Limousin">Patricia Limousin</name>
<affiliation wicri:level="1"><country xml:lang="fr">France</country>
<wicri:regionArea>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</wicri:regionArea>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hoffmann, Dominique" sort="Hoffmann, Dominique" uniqKey="Hoffmann D" first="Dominique" last="Hoffmann">Dominique Hoffmann</name>
<affiliation wicri:level="1"><country xml:lang="fr">France</country>
<wicri:regionArea>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</wicri:regionArea>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Benazzouz, Abdelhamid" sort="Benazzouz, Abdelhamid" uniqKey="Benazzouz A" first="Abdelhamid" last="Benazzouz">Abdelhamid Benazzouz</name>
<affiliation wicri:level="1"><country xml:lang="fr">France</country>
<wicri:regionArea>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</wicri:regionArea>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Benabid, Alim Ouis" sort="Benabid, Alim Ouis" uniqKey="Benabid A" first="Alim-Louis" last="Benabid">Alim-Louis Benabid</name>
<affiliation wicri:level="1"><country xml:lang="fr">France</country>
<wicri:regionArea>Department of Clinical and Biological Neurosciences and INSERM U318, Joseph Fourier University of Grenoble</wicri:regionArea>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
<wicri:noRegion>Joseph Fourier University of Grenoble</wicri:noRegion>
<placeName><settlement type="city">Grenoble</settlement>
<region type="region" nuts="2">Auvergne-Rhône-Alpes</region>
<region type="old region" nuts="2">Rhône-Alpes</region>
</placeName>
<orgName type="hospital" n="4">Centre hospitalier universitaire Grenoble Alpes</orgName>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Movement Disorders</title>
<title level="j" type="sub">Official Journal of the Movement Disorder Society</title>
<title level="j" type="abbrev">Mov. Disord.</title>
<idno type="ISSN">0885-3185</idno>
<idno type="eISSN">1531-8257</idno>
<imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher>
<pubPlace>Hoboken</pubPlace>
<date type="published" when="1998-07">1998-07</date>
<biblScope unit="vol">13</biblScope>
<biblScope unit="issue">4</biblScope>
<biblScope unit="page" from="648">648</biblScope>
<biblScope unit="page" to="652">652</biblScope>
</imprint>
<idno type="ISSN">0885-3185</idno>
</series>
<idno type="istex">A3E18445A389F4FC66F38749E041592C1C5AE95A</idno>
<idno type="DOI">10.1002/mds.870130407</idno>
<idno type="ArticleID">MDS870130407</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antiparkinson Agents (administration & dosage)</term>
<term>Antiparkinson Agents (adverse effects)</term>
<term>Combined Modality Therapy</term>
<term>Dominance, Cerebral (drug effects)</term>
<term>Dominance, Cerebral (physiology)</term>
<term>Dyskinesia, Drug-Induced (diagnosis)</term>
<term>Dyskinesia, Drug-Induced (physiopathology)</term>
<term>Dyskinesia, Drug-Induced (therapy)</term>
<term>Electric Stimulation Therapy</term>
<term>Electrical stimulation</term>
<term>Electrodes, Implanted</term>
<term>Globus Pallidus (drug effects)</term>
<term>Globus Pallidus (physiopathology)</term>
<term>Humans</term>
<term>Internal pallidum</term>
<term>Levodopa</term>
<term>Levodopa (administration & dosage)</term>
<term>Levodopa (adverse effects)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Parkinson Disease (physiopathology)</term>
<term>Parkinson Disease (therapy)</term>
<term>Parkinson's disease</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Antiparkinson Agents</term>
<term>Levodopa</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Antiparkinson Agents</term>
<term>Levodopa</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Dyskinesia, Drug-Induced</term>
</keywords>
<keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Dominance, Cerebral</term>
<term>Globus Pallidus</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Dominance, Cerebral</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Dyskinesia, Drug-Induced</term>
<term>Globus Pallidus</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Dyskinesia, Drug-Induced</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Combined Modality Therapy</term>
<term>Electric Stimulation Therapy</term>
<term>Electrodes, Implanted</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">We report three patients with bilateral GPi stimulation for stage 4 Parkinson's disease (PD) with severe levodopa‐induced dyskinesias (LID). In all three it was possible to completely inhibit LID using high‐stimulation parameters. Parallel to complete inhibition of LID, an inhibition of the anti‐akinetic effect of levodopa was observed, whereas, at the same time, rigidity was markedly improved. GPi stimulation is adaptable over time, and stimulation parameters have to be programmed according to off‐and on‐period motor symptoms. The main interest of stimulation is the possibility of finding a compromise between LID alleviation in on‐phase without loss of the beneficial motor effects and improvement in parkinsonism in off‐phase. In some patients, residual dyskinesias have to be accepted so as not to aggravate on‐period motor symptoms by a presumed overinhibition of basal ganglia outflow.</div>
</front>
</TEI>
</ISTEX>
</double>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Main/Curation

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 004F76 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Curation/biblio.hfd -nk 004F76 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Santé
   |area=    MovDisordV3
   |flux=    Main
   |étape=   Curation
   |type=    RBID
   |clé=     ISTEX:A3E18445A389F4FC66F38749E041592C1C5AE95A
   |texte=   Inhibition of levodopa effects by internal pallidal stimulation
}}

This area was generated with Dilib version V0.6.23.
Data generation: Sun Jul 3 12:29:32 2016. Site generation: Wed Feb 14 10:52:30 2024

	Movement Disorders (revue)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Movement Disorders (revue)

Inhibition of levodopa effects by internal pallidal stimulation

Inhibition of levodopa effects by internal pallidal stimulation

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri