Synchronized brain network underlying postural tremor in Wilson's disease
Identifieur interne : 003159 ( Main/Curation ); précédent : 003158; suivant : 003160Synchronized brain network underlying postural tremor in Wilson's disease
Auteurs : Martin Südmeyer [Allemagne] ; Bettina Pollok [Allemagne] ; Harald Hefter [Allemagne] ; Joachim Gross [Allemagne] ; Markus Butz [Allemagne] ; Lars Wojtecki [Allemagne] ; Lars Timmermann [Allemagne] ; Alfons Schnitzler [Allemagne]Source :
- Movement Disorders [ 0885-3185 ] ; 2006-11.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Cuivre.
English descriptors
- KwdEn :
- Adult, Brain (pathology), Brain (physiopathology), Brain Mapping, Coherence, Copper, Electroencephalography (methods), Electromyography (methods), Encephalon, Evoked Potentials, Motor (physiology), Evoked Potentials, Motor (radiation effects), Hepatolenticular Degeneration (complications), Humans, Magnetic Resonance Imaging (methods), Magnetoencephalography, Male, Middle Aged, Muscle, Skeletal (physiopathology), Nerve Net (physiopathology), Nervous system diseases, Nuclear magnetic resonance imaging, Posture, Tremor, Tremor (etiology), Wilson disease, Wilson's disease, coherence, magnetic resonance imaging, magnetoencephalography, tremor.
- MESH :
- complications : Hepatolenticular Degeneration.
- etiology : Tremor.
- methods : Electroencephalography, Electromyography, Magnetic Resonance Imaging.
- pathology : Brain.
- physiology : Evoked Potentials, Motor.
- physiopathology : Brain, Muscle, Skeletal, Nerve Net.
- radiation effects : Evoked Potentials, Motor.
- Adult, Brain Mapping, Humans, Male, Middle Aged, Posture.
Abstract
Common neurological manifestation of Wilson's disease (WD) is a postural tremor of the upper extremities. Recently, the primary sensorimotor cortex (S1/M1) has been shown to be involved in WD postural tremor generation. However, neuropathological changes in WD are mostly observed in subcortical structures. We therefore aimed to investigate whether S1/M1 may be functionally interconnected with other brain areas. In five WD patients, we used magnetoencephalography and surface electromyography (EMG) to record simultaneously cerebral neuronal activity and muscular activity during sustained posture of the right forearm. As demonstrated previously, the strongest coupling to tremor EMG was observed in the contralateral S1/M1. This area was taken as reference in order to identify and localize cerebro–cerebral coherence at tremor frequency and its first harmonic. The analysis revealed significant coherence within an oscillatory network including S1/M1, higher cortical motor areas (premotor cortex, PM; supplementary motor area, SMA), posterior parietal cortex (PPC) and thalamus contralateral as well as the cerebellum ipsilateral to the tremor forearm. Flow of information was mainly of bidirectional nature. Taken together, our results indicate that WD postural tremor is generated within a synchronized cerebello–thalamo–cortical network, comprising S1/M1, higher cortical motor areas (SMA, PM), and PPC. © 2006 Movement Disorder Society
Url:
DOI: 10.1002/mds.21104
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: Pour aller vers cette notice dans l'étape Curation :001D47
- to stream Istex, to step Curation: Pour aller vers cette notice dans l'étape Curation :001D47
- to stream Istex, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :001C18
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :002A76
- to stream PubMed, to step Curation: Pour aller vers cette notice dans l'étape Curation :002A76
- to stream PubMed, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :002A65
- to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :001863
- to stream Ncbi, to step Curation: Pour aller vers cette notice dans l'étape Curation :001863
- to stream Ncbi, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :001863
- to stream Main, to step Merge: Pour aller vers cette notice dans l'étape Curation :004472
- to stream PascalFrancis, to step Corpus: Pour aller vers cette notice dans l'étape Curation :001910
- to stream PascalFrancis, to step Curation: Pour aller vers cette notice dans l'étape Curation :001411
- to stream PascalFrancis, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :001876
- to stream Main, to step Merge: Pour aller vers cette notice dans l'étape Curation :004971
Links to Exploration step
ISTEX:32BE7C3E01E6FEDCC0B73B6F7DD87EA428F081D0Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Synchronized brain network underlying postural tremor in Wilson's disease</title>
<author><name sortKey="Sudmeyer, Martin" sort="Sudmeyer, Martin" uniqKey="Sudmeyer M" first="Martin" last="Südmeyer">Martin Südmeyer</name>
</author>
<author><name sortKey="Pollok, Bettina" sort="Pollok, Bettina" uniqKey="Pollok B" first="Bettina" last="Pollok">Bettina Pollok</name>
</author>
<author><name sortKey="Hefter, Harald" sort="Hefter, Harald" uniqKey="Hefter H" first="Harald" last="Hefter">Harald Hefter</name>
</author>
<author><name sortKey="Gross, Joachim" sort="Gross, Joachim" uniqKey="Gross J" first="Joachim" last="Gross">Joachim Gross</name>
</author>
<author><name sortKey="Butz, Markus" sort="Butz, Markus" uniqKey="Butz M" first="Markus" last="Butz">Markus Butz</name>
</author>
<author><name sortKey="Wojtecki, Lars" sort="Wojtecki, Lars" uniqKey="Wojtecki L" first="Lars" last="Wojtecki">Lars Wojtecki</name>
</author>
<author><name sortKey="Timmermann, Lars" sort="Timmermann, Lars" uniqKey="Timmermann L" first="Lars" last="Timmermann">Lars Timmermann</name>
</author>
<author><name sortKey="Schnitzler, Alfons" sort="Schnitzler, Alfons" uniqKey="Schnitzler A" first="Alfons" last="Schnitzler">Alfons Schnitzler</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:32BE7C3E01E6FEDCC0B73B6F7DD87EA428F081D0</idno>
<date when="2006" year="2006">2006</date>
<idno type="doi">10.1002/mds.21104</idno>
<idno type="url">https://api.istex.fr/document/32BE7C3E01E6FEDCC0B73B6F7DD87EA428F081D0/fulltext/pdf</idno>
<idno type="wicri:Area/Istex/Corpus">001D47</idno>
<idno type="wicri:Area/Istex/Curation">001D47</idno>
<idno type="wicri:Area/Istex/Checkpoint">001C18</idno>
<idno type="wicri:doubleKey">0885-3185:2006:Sudmeyer M:synchronized:brain:network</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:16991150</idno>
<idno type="wicri:Area/PubMed/Corpus">002A76</idno>
<idno type="wicri:Area/PubMed/Curation">002A76</idno>
<idno type="wicri:Area/PubMed/Checkpoint">002A65</idno>
<idno type="wicri:Area/Ncbi/Merge">001863</idno>
<idno type="wicri:Area/Ncbi/Curation">001863</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">001863</idno>
<idno type="wicri:doubleKey">0885-3185:2006:Sudmeyer M:synchronized:brain:network</idno>
<idno type="wicri:Area/Main/Merge">004472</idno>
<idno type="wicri:source">INIST</idno>
<idno type="RBID">Pascal:07-0021721</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">001910</idno>
<idno type="wicri:Area/PascalFrancis/Curation">001411</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">001876</idno>
<idno type="wicri:doubleKey">0885-3185:2006:Sudmeyer M:synchronized:brain:network</idno>
<idno type="wicri:Area/Main/Merge">004971</idno>
<idno type="wicri:Area/Main/Curation">003159</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Synchronized brain network underlying postural tremor in Wilson's disease</title>
<author><name sortKey="Sudmeyer, Martin" sort="Sudmeyer, Martin" uniqKey="Sudmeyer M" first="Martin" last="Südmeyer">Martin Südmeyer</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurology, Heinrich Heine University, Düsseldorf</wicri:regionArea>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Pollok, Bettina" sort="Pollok, Bettina" uniqKey="Pollok B" first="Bettina" last="Pollok">Bettina Pollok</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurology, Heinrich Heine University, Düsseldorf</wicri:regionArea>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hefter, Harald" sort="Hefter, Harald" uniqKey="Hefter H" first="Harald" last="Hefter">Harald Hefter</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurology, Heinrich Heine University, Düsseldorf</wicri:regionArea>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Gross, Joachim" sort="Gross, Joachim" uniqKey="Gross J" first="Joachim" last="Gross">Joachim Gross</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurology, Heinrich Heine University, Düsseldorf</wicri:regionArea>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Butz, Markus" sort="Butz, Markus" uniqKey="Butz M" first="Markus" last="Butz">Markus Butz</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurology, Heinrich Heine University, Düsseldorf</wicri:regionArea>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Wojtecki, Lars" sort="Wojtecki, Lars" uniqKey="Wojtecki L" first="Lars" last="Wojtecki">Lars Wojtecki</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurology, Heinrich Heine University, Düsseldorf</wicri:regionArea>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Timmermann, Lars" sort="Timmermann, Lars" uniqKey="Timmermann L" first="Lars" last="Timmermann">Lars Timmermann</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurology, Heinrich Heine University, Düsseldorf</wicri:regionArea>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Schnitzler, Alfons" sort="Schnitzler, Alfons" uniqKey="Schnitzler A" first="Alfons" last="Schnitzler">Alfons Schnitzler</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurology, Heinrich Heine University, Düsseldorf</wicri:regionArea>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Movement Disorders</title>
<title level="j" type="sub">Official Journal of the Movement Disorder Society</title>
<title level="j" type="abbrev">Mov. Disord.</title>
<idno type="ISSN">0885-3185</idno>
<idno type="eISSN">1531-8257</idno>
<imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher>
<pubPlace>Hoboken</pubPlace>
<date type="published" when="2006-11">2006-11</date>
<biblScope unit="vol">21</biblScope>
<biblScope unit="issue">11</biblScope>
<biblScope unit="page" from="1935">1935</biblScope>
<biblScope unit="page" to="1940">1940</biblScope>
</imprint>
<idno type="ISSN">0885-3185</idno>
</series>
<idno type="istex">32BE7C3E01E6FEDCC0B73B6F7DD87EA428F081D0</idno>
<idno type="DOI">10.1002/mds.21104</idno>
<idno type="ArticleID">MDS21104</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Brain (pathology)</term>
<term>Brain (physiopathology)</term>
<term>Brain Mapping</term>
<term>Coherence</term>
<term>Copper</term>
<term>Electroencephalography (methods)</term>
<term>Electromyography (methods)</term>
<term>Encephalon</term>
<term>Evoked Potentials, Motor (physiology)</term>
<term>Evoked Potentials, Motor (radiation effects)</term>
<term>Hepatolenticular Degeneration (complications)</term>
<term>Humans</term>
<term>Magnetic Resonance Imaging (methods)</term>
<term>Magnetoencephalography</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Muscle, Skeletal (physiopathology)</term>
<term>Nerve Net (physiopathology)</term>
<term>Nervous system diseases</term>
<term>Nuclear magnetic resonance imaging</term>
<term>Posture</term>
<term>Tremor</term>
<term>Tremor (etiology)</term>
<term>Wilson disease</term>
<term>Wilson's disease</term>
<term>coherence</term>
<term>magnetic resonance imaging</term>
<term>magnetoencephalography</term>
<term>tremor</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Hepatolenticular Degeneration</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Tremor</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Electroencephalography</term>
<term>Electromyography</term>
<term>Magnetic Resonance Imaging</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Brain</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Evoked Potentials, Motor</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Brain</term>
<term>Muscle, Skeletal</term>
<term>Nerve Net</term>
</keywords>
<keywords scheme="MESH" qualifier="radiation effects" xml:lang="en"><term>Evoked Potentials, Motor</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Brain Mapping</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Posture</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Cohérence</term>
<term>Cuivre</term>
<term>Encéphale</term>
<term>Imagerie RMN</term>
<term>Magnétoencéphalographie</term>
<term>Système nerveux pathologie</term>
<term>Tremblement</term>
<term>Wilson maladie</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Cuivre</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Common neurological manifestation of Wilson's disease (WD) is a postural tremor of the upper extremities. Recently, the primary sensorimotor cortex (S1/M1) has been shown to be involved in WD postural tremor generation. However, neuropathological changes in WD are mostly observed in subcortical structures. We therefore aimed to investigate whether S1/M1 may be functionally interconnected with other brain areas. In five WD patients, we used magnetoencephalography and surface electromyography (EMG) to record simultaneously cerebral neuronal activity and muscular activity during sustained posture of the right forearm. As demonstrated previously, the strongest coupling to tremor EMG was observed in the contralateral S1/M1. This area was taken as reference in order to identify and localize cerebro–cerebral coherence at tremor frequency and its first harmonic. The analysis revealed significant coherence within an oscillatory network including S1/M1, higher cortical motor areas (premotor cortex, PM; supplementary motor area, SMA), posterior parietal cortex (PPC) and thalamus contralateral as well as the cerebellum ipsilateral to the tremor forearm. Flow of information was mainly of bidirectional nature. Taken together, our results indicate that WD postural tremor is generated within a synchronized cerebello–thalamo–cortical network, comprising S1/M1, higher cortical motor areas (SMA, PM), and PPC. © 2006 Movement Disorder Society</div>
</front>
</TEI>
<double idat="0885-3185:2006:Sudmeyer M:synchronized:brain:network"><INIST><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Synchronized brain network underlying postural tremor in Wilson's disease</title>
<author><name sortKey="Sudmeyer, Martin" sort="Sudmeyer, Martin" uniqKey="Sudmeyer M" first="Martin" last="Südmeyer">Martin Südmeyer</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Heinrich Heine University</s1>
<s2>Düsseldorf</s2>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
<wicri:noRegion>Heinrich Heine University</wicri:noRegion>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Pollok, Bettina" sort="Pollok, Bettina" uniqKey="Pollok B" first="Bettina" last="Pollok">Bettina Pollok</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Heinrich Heine University</s1>
<s2>Düsseldorf</s2>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
<wicri:noRegion>Heinrich Heine University</wicri:noRegion>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hefter, Harald" sort="Hefter, Harald" uniqKey="Hefter H" first="Harald" last="Hefter">Harald Hefter</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Heinrich Heine University</s1>
<s2>Düsseldorf</s2>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
<wicri:noRegion>Heinrich Heine University</wicri:noRegion>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Gross, Joachim" sort="Gross, Joachim" uniqKey="Gross J" first="Joachim" last="Gross">Joachim Gross</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Heinrich Heine University</s1>
<s2>Düsseldorf</s2>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
<wicri:noRegion>Heinrich Heine University</wicri:noRegion>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Butz, Markus" sort="Butz, Markus" uniqKey="Butz M" first="Markus" last="Butz">Markus Butz</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Heinrich Heine University</s1>
<s2>Düsseldorf</s2>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
<wicri:noRegion>Heinrich Heine University</wicri:noRegion>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Wojtecki, Lars" sort="Wojtecki, Lars" uniqKey="Wojtecki L" first="Lars" last="Wojtecki">Lars Wojtecki</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Heinrich Heine University</s1>
<s2>Düsseldorf</s2>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
<wicri:noRegion>Heinrich Heine University</wicri:noRegion>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Timmermann, Lars" sort="Timmermann, Lars" uniqKey="Timmermann L" first="Lars" last="Timmermann">Lars Timmermann</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Heinrich Heine University</s1>
<s2>Düsseldorf</s2>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
<wicri:noRegion>Heinrich Heine University</wicri:noRegion>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Schnitzler, Alfons" sort="Schnitzler, Alfons" uniqKey="Schnitzler A" first="Alfons" last="Schnitzler">Alfons Schnitzler</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Heinrich Heine University</s1>
<s2>Düsseldorf</s2>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
<wicri:noRegion>Heinrich Heine University</wicri:noRegion>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">07-0021721</idno>
<date when="2006">2006</date>
<idno type="stanalyst">PASCAL 07-0021721 INIST</idno>
<idno type="RBID">Pascal:07-0021721</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">001910</idno>
<idno type="wicri:Area/PascalFrancis/Curation">001411</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">001876</idno>
<idno type="wicri:doubleKey">0885-3185:2006:Sudmeyer M:synchronized:brain:network</idno>
<idno type="wicri:Area/Main/Merge">004971</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Synchronized brain network underlying postural tremor in Wilson's disease</title>
<author><name sortKey="Sudmeyer, Martin" sort="Sudmeyer, Martin" uniqKey="Sudmeyer M" first="Martin" last="Südmeyer">Martin Südmeyer</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Heinrich Heine University</s1>
<s2>Düsseldorf</s2>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
<wicri:noRegion>Heinrich Heine University</wicri:noRegion>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Pollok, Bettina" sort="Pollok, Bettina" uniqKey="Pollok B" first="Bettina" last="Pollok">Bettina Pollok</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Heinrich Heine University</s1>
<s2>Düsseldorf</s2>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
<wicri:noRegion>Heinrich Heine University</wicri:noRegion>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hefter, Harald" sort="Hefter, Harald" uniqKey="Hefter H" first="Harald" last="Hefter">Harald Hefter</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Heinrich Heine University</s1>
<s2>Düsseldorf</s2>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
<wicri:noRegion>Heinrich Heine University</wicri:noRegion>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Gross, Joachim" sort="Gross, Joachim" uniqKey="Gross J" first="Joachim" last="Gross">Joachim Gross</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Heinrich Heine University</s1>
<s2>Düsseldorf</s2>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
<wicri:noRegion>Heinrich Heine University</wicri:noRegion>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Butz, Markus" sort="Butz, Markus" uniqKey="Butz M" first="Markus" last="Butz">Markus Butz</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Heinrich Heine University</s1>
<s2>Düsseldorf</s2>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
<wicri:noRegion>Heinrich Heine University</wicri:noRegion>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Wojtecki, Lars" sort="Wojtecki, Lars" uniqKey="Wojtecki L" first="Lars" last="Wojtecki">Lars Wojtecki</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Heinrich Heine University</s1>
<s2>Düsseldorf</s2>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
<wicri:noRegion>Heinrich Heine University</wicri:noRegion>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Timmermann, Lars" sort="Timmermann, Lars" uniqKey="Timmermann L" first="Lars" last="Timmermann">Lars Timmermann</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Heinrich Heine University</s1>
<s2>Düsseldorf</s2>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
<wicri:noRegion>Heinrich Heine University</wicri:noRegion>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Schnitzler, Alfons" sort="Schnitzler, Alfons" uniqKey="Schnitzler A" first="Alfons" last="Schnitzler">Alfons Schnitzler</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Neurology, Heinrich Heine University</s1>
<s2>Düsseldorf</s2>
<s3>DEU</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
<wicri:noRegion>Heinrich Heine University</wicri:noRegion>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Movement disorders</title>
<title level="j" type="abbreviated">Mov. disord.</title>
<idno type="ISSN">0885-3185</idno>
<imprint><date when="2006">2006</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Movement disorders</title>
<title level="j" type="abbreviated">Mov. disord.</title>
<idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Coherence</term>
<term>Copper</term>
<term>Encephalon</term>
<term>Magnetoencephalography</term>
<term>Nervous system diseases</term>
<term>Nuclear magnetic resonance imaging</term>
<term>Tremor</term>
<term>Wilson disease</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Système nerveux pathologie</term>
<term>Tremblement</term>
<term>Wilson maladie</term>
<term>Encéphale</term>
<term>Cohérence</term>
<term>Magnétoencéphalographie</term>
<term>Imagerie RMN</term>
<term>Cuivre</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Cuivre</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Common neurological manifestation of Wilson's disease (WD) is a postural tremor of the upper extremities. Recently, the primary sensorimotor cortex (S1/M1) has been shown to be involved in WD postural tremor generation. However, neuropathological changes in WD are mostly observed in subcortical structures. We therefore aimed to investigate whether S1/M1 may be functionally interconnected with other brain areas. In five WD patients, we used magnetoencephalography and surface electromyography (EMG) to record simultaneously cerebral neuronal activity and muscular activity during sustained posture of the right forearm. As demonstrated previously, the strongest coupling to tremor EMG was observed in the contralateral S1/M1. This area was taken as reference in order to identify and localize cerebro-cerebral coherence at tremor frequency and its first harmonic. The analysis revealed significant coherence within an oscillatory network including S1/M1, higher cortical motor areas (premotor cortex, PM; supplementary motor area, SMA), posterior parietal cortex (PPC) and thalamus contralateral as well as the cerebellum ipsilateral to the tremor forearm. Flow of information was mainly of bidirectional nature. Taken together, our results indicate that WD postural tremor is generated within a synchronized cerebello-thalamo-cortical network, comprising S1/M1, higher cortical motor areas (SMA, PM), and PPC.</div>
</front>
</TEI>
</INIST>
<ISTEX><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Synchronized brain network underlying postural tremor in Wilson's disease</title>
<author><name sortKey="Sudmeyer, Martin" sort="Sudmeyer, Martin" uniqKey="Sudmeyer M" first="Martin" last="Südmeyer">Martin Südmeyer</name>
</author>
<author><name sortKey="Pollok, Bettina" sort="Pollok, Bettina" uniqKey="Pollok B" first="Bettina" last="Pollok">Bettina Pollok</name>
</author>
<author><name sortKey="Hefter, Harald" sort="Hefter, Harald" uniqKey="Hefter H" first="Harald" last="Hefter">Harald Hefter</name>
</author>
<author><name sortKey="Gross, Joachim" sort="Gross, Joachim" uniqKey="Gross J" first="Joachim" last="Gross">Joachim Gross</name>
</author>
<author><name sortKey="Butz, Markus" sort="Butz, Markus" uniqKey="Butz M" first="Markus" last="Butz">Markus Butz</name>
</author>
<author><name sortKey="Wojtecki, Lars" sort="Wojtecki, Lars" uniqKey="Wojtecki L" first="Lars" last="Wojtecki">Lars Wojtecki</name>
</author>
<author><name sortKey="Timmermann, Lars" sort="Timmermann, Lars" uniqKey="Timmermann L" first="Lars" last="Timmermann">Lars Timmermann</name>
</author>
<author><name sortKey="Schnitzler, Alfons" sort="Schnitzler, Alfons" uniqKey="Schnitzler A" first="Alfons" last="Schnitzler">Alfons Schnitzler</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:32BE7C3E01E6FEDCC0B73B6F7DD87EA428F081D0</idno>
<date when="2006" year="2006">2006</date>
<idno type="doi">10.1002/mds.21104</idno>
<idno type="url">https://api.istex.fr/document/32BE7C3E01E6FEDCC0B73B6F7DD87EA428F081D0/fulltext/pdf</idno>
<idno type="wicri:Area/Istex/Corpus">001D47</idno>
<idno type="wicri:Area/Istex/Curation">001D47</idno>
<idno type="wicri:Area/Istex/Checkpoint">001C18</idno>
<idno type="wicri:doubleKey">0885-3185:2006:Sudmeyer M:synchronized:brain:network</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:16991150</idno>
<idno type="wicri:Area/PubMed/Corpus">002A76</idno>
<idno type="wicri:Area/PubMed/Curation">002A76</idno>
<idno type="wicri:Area/PubMed/Checkpoint">002A65</idno>
<idno type="wicri:Area/Ncbi/Merge">001863</idno>
<idno type="wicri:Area/Ncbi/Curation">001863</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">001863</idno>
<idno type="wicri:doubleKey">0885-3185:2006:Sudmeyer M:synchronized:brain:network</idno>
<idno type="wicri:Area/Main/Merge">004472</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Synchronized brain network underlying postural tremor in Wilson's disease</title>
<author><name sortKey="Sudmeyer, Martin" sort="Sudmeyer, Martin" uniqKey="Sudmeyer M" first="Martin" last="Südmeyer">Martin Südmeyer</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurology, Heinrich Heine University, Düsseldorf</wicri:regionArea>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Pollok, Bettina" sort="Pollok, Bettina" uniqKey="Pollok B" first="Bettina" last="Pollok">Bettina Pollok</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurology, Heinrich Heine University, Düsseldorf</wicri:regionArea>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hefter, Harald" sort="Hefter, Harald" uniqKey="Hefter H" first="Harald" last="Hefter">Harald Hefter</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurology, Heinrich Heine University, Düsseldorf</wicri:regionArea>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Gross, Joachim" sort="Gross, Joachim" uniqKey="Gross J" first="Joachim" last="Gross">Joachim Gross</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurology, Heinrich Heine University, Düsseldorf</wicri:regionArea>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Butz, Markus" sort="Butz, Markus" uniqKey="Butz M" first="Markus" last="Butz">Markus Butz</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurology, Heinrich Heine University, Düsseldorf</wicri:regionArea>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Wojtecki, Lars" sort="Wojtecki, Lars" uniqKey="Wojtecki L" first="Lars" last="Wojtecki">Lars Wojtecki</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurology, Heinrich Heine University, Düsseldorf</wicri:regionArea>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Timmermann, Lars" sort="Timmermann, Lars" uniqKey="Timmermann L" first="Lars" last="Timmermann">Lars Timmermann</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurology, Heinrich Heine University, Düsseldorf</wicri:regionArea>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Schnitzler, Alfons" sort="Schnitzler, Alfons" uniqKey="Schnitzler A" first="Alfons" last="Schnitzler">Alfons Schnitzler</name>
<affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Neurology, Heinrich Heine University, Düsseldorf</wicri:regionArea>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
<wicri:noRegion>Düsseldorf</wicri:noRegion>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Movement Disorders</title>
<title level="j" type="sub">Official Journal of the Movement Disorder Society</title>
<title level="j" type="abbrev">Mov. Disord.</title>
<idno type="ISSN">0885-3185</idno>
<idno type="eISSN">1531-8257</idno>
<imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher>
<pubPlace>Hoboken</pubPlace>
<date type="published" when="2006-11">2006-11</date>
<biblScope unit="vol">21</biblScope>
<biblScope unit="issue">11</biblScope>
<biblScope unit="page" from="1935">1935</biblScope>
<biblScope unit="page" to="1940">1940</biblScope>
</imprint>
<idno type="ISSN">0885-3185</idno>
</series>
<idno type="istex">32BE7C3E01E6FEDCC0B73B6F7DD87EA428F081D0</idno>
<idno type="DOI">10.1002/mds.21104</idno>
<idno type="ArticleID">MDS21104</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0885-3185</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Brain (pathology)</term>
<term>Brain (physiopathology)</term>
<term>Brain Mapping</term>
<term>Electroencephalography (methods)</term>
<term>Electromyography (methods)</term>
<term>Evoked Potentials, Motor (physiology)</term>
<term>Evoked Potentials, Motor (radiation effects)</term>
<term>Hepatolenticular Degeneration (complications)</term>
<term>Humans</term>
<term>Magnetic Resonance Imaging (methods)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Muscle, Skeletal (physiopathology)</term>
<term>Nerve Net (physiopathology)</term>
<term>Posture</term>
<term>Tremor (etiology)</term>
<term>Wilson's disease</term>
<term>coherence</term>
<term>magnetic resonance imaging</term>
<term>magnetoencephalography</term>
<term>tremor</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Hepatolenticular Degeneration</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Tremor</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Electroencephalography</term>
<term>Electromyography</term>
<term>Magnetic Resonance Imaging</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Brain</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Evoked Potentials, Motor</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Brain</term>
<term>Muscle, Skeletal</term>
<term>Nerve Net</term>
</keywords>
<keywords scheme="MESH" qualifier="radiation effects" xml:lang="en"><term>Evoked Potentials, Motor</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Brain Mapping</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Posture</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Common neurological manifestation of Wilson's disease (WD) is a postural tremor of the upper extremities. Recently, the primary sensorimotor cortex (S1/M1) has been shown to be involved in WD postural tremor generation. However, neuropathological changes in WD are mostly observed in subcortical structures. We therefore aimed to investigate whether S1/M1 may be functionally interconnected with other brain areas. In five WD patients, we used magnetoencephalography and surface electromyography (EMG) to record simultaneously cerebral neuronal activity and muscular activity during sustained posture of the right forearm. As demonstrated previously, the strongest coupling to tremor EMG was observed in the contralateral S1/M1. This area was taken as reference in order to identify and localize cerebro–cerebral coherence at tremor frequency and its first harmonic. The analysis revealed significant coherence within an oscillatory network including S1/M1, higher cortical motor areas (premotor cortex, PM; supplementary motor area, SMA), posterior parietal cortex (PPC) and thalamus contralateral as well as the cerebellum ipsilateral to the tremor forearm. Flow of information was mainly of bidirectional nature. Taken together, our results indicate that WD postural tremor is generated within a synchronized cerebello–thalamo–cortical network, comprising S1/M1, higher cortical motor areas (SMA, PM), and PPC. © 2006 Movement Disorder Society</div>
</front>
</TEI>
</ISTEX>
</double>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Main/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003159 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Curation/biblio.hfd -nk 003159 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Santé |area= MovDisordV3 |flux= Main |étape= Curation |type= RBID |clé= ISTEX:32BE7C3E01E6FEDCC0B73B6F7DD87EA428F081D0 |texte= Synchronized brain network underlying postural tremor in Wilson's disease }}
This area was generated with Dilib version V0.6.23. |