MovDisordV3, Main, Curation, bibRecord, 002260

Impairments of speed and amplitude of movement in Parkinson's disease: A pilot study

Identifieur interne : 002260 ( Main/Curation ); précédent : 002259; suivant : 002261

Impairments of speed and amplitude of movement in Parkinson's disease: A pilot study

Auteurs : Alberto J. Espay [Canada, États-Unis] ; Dorcas E. Beaton [Canada] ; Francesca Morgante [Canada, Italie] ; Carolyn A. Gunraj [Canada] ; Anthony E. Lang [Canada] ; Robert Chen [Canada]

Source :

Movement Disorders [ 0885-3185 ] ; 2009-05-15.

RBID : ISTEX:E78B943017DC4445EA9ED4F232C3C26C3C38391D

Descripteurs français

Pascal (Inist)
- Amplitude, Echelle d'évaluation, Maladie de Parkinson, Pathologie du système nerveux, Vitesse déplacement.

English descriptors

KwdEn :
- Aged, Aged, 80 and over, Amplitude, Biomechanical Phenomena, Cross-Sectional Studies, Disability Evaluation, Evaluation scale, Female, Humans, Hypokinesia (etiology), Male, Middle Aged, Nervous system diseases, Parkinson Disease (complications), Parkinson disease, Parkinson's disease, Pilot Projects, Psychomotor Performance (physiology), Reproducibility of Results, Severity of Illness Index, Speed, Task Performance and Analysis, bradykinesia, unified Parkinson's disease rating scale.
MESH :
- complications : Parkinson Disease.
- etiology : Hypokinesia.
- physiology : Psychomotor Performance.
- Aged, Aged, 80 and over, Biomechanical Phenomena, Cross-Sectional Studies, Disability Evaluation, Female, Humans, Male, Middle Aged, Pilot Projects, Reproducibility of Results, Severity of Illness Index, Task Performance and Analysis.

Abstract

Bradykinesia, characterized by slowness and decreased amplitude of movement, is often considered the most important deficit in Parkinson's disease (PD). The current clinical rating of bradykinesia in PD, based on the motor subscale of the Unified Parkinson's disease Rating Scale (UPDRS‐III), does not individually weigh the impairments in speed and amplitude of rapid alternating movements. We sought to categorize movement in PD to determine whether speed and amplitude have different relationships to current measures of motor impairment and disability. Categories of speed and amplitude (normal, slow/low, and very‐slow/very‐low) were ascertained using an electromagnetic tracking device. Amplitude was disproportionally more affected than speed in the “off” state. UPDRS‐III and the Schwab & England disability scale were worst in patients with very impaired amplitude and best in patients with normal amplitude. A similarly graded relationship was not found for categories of speed impairment. The examiner clinical global impression of change mirrored “off” state amplitude but not speed categories. Levodopa, however, normalized speed to a greater extent than amplitude. Our observations suggest that amplitude and speed impairments may be associated with different functional aspects in PD and deserve separate clinical assessment. © 2009 Movement Disorder Society

Url:

https://api.istex.fr/document/E78B943017DC4445EA9ED4F232C3C26C3C38391D/fulltext/pdf

DOI: 10.1002/mds.22480

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ISTEX:E78B943017DC4445EA9ED4F232C3C26C3C38391D

Le document en format XML

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<front><div type="abstract" xml:lang="en">Bradykinesia, characterized by slowness and decreased amplitude of movement, is often considered the most important deficit in Parkinson's disease (PD). The current clinical rating of bradykinesia in PD, based on the motor subscale of the Unified Parkinson's disease Rating Scale (UPDRS‐III), does not individually weigh the impairments in speed and amplitude of rapid alternating movements. We sought to categorize movement in PD to determine whether speed and amplitude have different relationships to current measures of motor impairment and disability. Categories of speed and amplitude (normal, slow/low, and very‐slow/very‐low) were ascertained using an electromagnetic tracking device. Amplitude was disproportionally more affected than speed in the “off” state. UPDRS‐III and the Schwab & England disability scale were worst in patients with very impaired amplitude and best in patients with normal amplitude. A similarly graded relationship was not found for categories of speed impairment. The examiner clinical global impression of change mirrored “off” state amplitude but not speed categories. Levodopa, however, normalized speed to a greater extent than amplitude. Our observations suggest that amplitude and speed impairments may be associated with different functional aspects in PD and deserve separate clinical assessment. © 2009 Movement Disorder Society</div>
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<front><div type="abstract" xml:lang="en">Bradykinesia, characterized by slowness and decreased amplitude of movement, is often considered the most important deficit in Parkinson's disease (PD). The current clinical rating of bradykinesia in PD, based on the motor subscale of the Unified Parkinson's disease Rating Scale (UPDRS-III), does not individually weigh the impairments in speed and amplitude of rapid alternating movements. We sought to categorize movement in PD to determine whether speed and amplitude have different relationships to current measures of motor impairment and disability. Categories of speed and amplitude (normal, slow/low, and very-slow/very-low) were ascertained using an electromagnetic tracking device. Amplitude was disproportionally more affected than speed in the "off" state. UPDRS-III and the Schwab & England disability scale were worst in patients with very impaired amplitude and best in patients with normal amplitude. A similarly graded relationship was not found for categories of speed impairment. The examiner clinical global impression of change mirrored "off" state amplitude but not speed categories. Levodopa, however, normalized speed to a greater extent than amplitude. Our observations suggest that amplitude and speed impairments may be associated with different functional aspects in PD and deserve separate clinical assessment.</div>
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<front><div type="abstract" xml:lang="en">Bradykinesia, characterized by slowness and decreased amplitude of movement, is often considered the most important deficit in Parkinson's disease (PD). The current clinical rating of bradykinesia in PD, based on the motor subscale of the Unified Parkinson's disease Rating Scale (UPDRS‐III), does not individually weigh the impairments in speed and amplitude of rapid alternating movements. We sought to categorize movement in PD to determine whether speed and amplitude have different relationships to current measures of motor impairment and disability. Categories of speed and amplitude (normal, slow/low, and very‐slow/very‐low) were ascertained using an electromagnetic tracking device. Amplitude was disproportionally more affected than speed in the “off” state. UPDRS‐III and the Schwab & England disability scale were worst in patients with very impaired amplitude and best in patients with normal amplitude. A similarly graded relationship was not found for categories of speed impairment. The examiner clinical global impression of change mirrored “off” state amplitude but not speed categories. Levodopa, however, normalized speed to a greater extent than amplitude. Our observations suggest that amplitude and speed impairments may be associated with different functional aspects in PD and deserve separate clinical assessment. © 2009 Movement Disorder Society</div>
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	Movement Disorders (revue)
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Movement Disorders (revue)

Impairments of speed and amplitude of movement in Parkinson's disease: A pilot study

Impairments of speed and amplitude of movement in Parkinson's disease: A pilot study

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