Movement Disorders (revue)

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Pathology of Symptomatic Tremors

Identifieur interne : 002927 ( Istex/Curation ); précédent : 002926; suivant : 002928

Pathology of Symptomatic Tremors

Auteurs : Marie Vidailhet [France] ; Charles-Pierre Jedynak [France] ; Pierre Pollak [France] ; Yves Agid [France]

Source :

RBID : ISTEX:17B82C89FC649CD5579C7E55FDEA099BC6EFA969

English descriptors

Abstract

Symptomatic tremors are labeled in the literature under different names including rubral tremor, midbrain tremor, thalamic tremor, myorhythmia, Holmes' tremor, cerebellar tremor, and goal‐directed tremor. The most common tremor is a delayed‐onset postural and action tremor with a low frequency of 3 Hz and a proximal distribution. Resting irregular tremor is sometimes present. Mild cerebellar dysmetria is often detected. The lesions are mainly located in the thalamus, the brain stem, and the cerebellum, with secondary interruption and degeneration of various pathways and olivary hypertrophy. The more consistent lesions are found in the cerebello‐thalamocortical and dentato‐rubro‐olivary pathways. The role of superimposed dysfunction of the nigrostriatal system may account for the rest component. The role of the basal ganglia in the emergence and control of tremor is poorly understood.

Url:
DOI: 10.1002/mds.870131309

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ISTEX:17B82C89FC649CD5579C7E55FDEA099BC6EFA969

Le document en format XML

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