Movement Disorders (revue)

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Core assessment program for intracerebral transplantation in Huntington's disease (CAPIT‐HD)

Identifieur interne : 001F47 ( Istex/Curation ); précédent : 001F46; suivant : 001F48

Core assessment program for intracerebral transplantation in Huntington's disease (CAPIT‐HD)

Auteurs : Quinn [Royaume-Uni] ; Richard Brown [Royaume-Uni] ; David Craufurd [Royaume-Uni] ; Serge Goldman [Belgique] ; John Hodges [Royaume-Uni] ; Karl Kieburtz [États-Unis] ; Olle Lindvall [Suède] ; John Macmillan ; Raymund Roos [Pays-Bas]

Source :

RBID : ISTEX:BB534630569F2E46A4D692973450FDF688DD74CD

English descriptors

Abstract

Studies in Parkinson's disease using the Core Assessment Program for Intracerebral Transplantation (CAPIT) protocol have demonstrated that grafts of embryonic mesencephalic cells into striatum can survive, grow, and exert useful clinical effects. Attention is now being directed toward neural grafting in other conditions, such as Huntington's disease. As a precondition for grafting of embryonic striatal cells into diseased striatum in this complex motor and psychiatric disorder, not only is further basic research needed, but also a thorough and wide‐ranging assessment protocol is essential. This article presents such a CAPIT‐HD assessment protocol.

Url:
DOI: 10.1002/mds.870110205

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ISTEX:BB534630569F2E46A4D692973450FDF688DD74CD

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John Macmillan
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<wicri:noCountry code="subField">Wales</wicri:noCountry>
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Le document en format XML

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<div type="abstract" xml:lang="en">Studies in Parkinson's disease using the Core Assessment Program for Intracerebral Transplantation (CAPIT) protocol have demonstrated that grafts of embryonic mesencephalic cells into striatum can survive, grow, and exert useful clinical effects. Attention is now being directed toward neural grafting in other conditions, such as Huntington's disease. As a precondition for grafting of embryonic striatal cells into diseased striatum in this complex motor and psychiatric disorder, not only is further basic research needed, but also a thorough and wide‐ranging assessment protocol is essential. This article presents such a CAPIT‐HD assessment protocol.</div>
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