Restless legs syndrome is a common feature of adult celiac disease
Identifieur interne : 001791 ( Istex/Curation ); précédent : 001790; suivant : 001792Restless legs syndrome is a common feature of adult celiac disease
Auteurs : Marcello Moccia [Italie] ; Maria Teresa Pellecchia [Italie] ; Roberto Erro [Italie] ; Fabiana Zingone [Italie] ; Sara Marelli [Italie] ; Damiano Giuseppe Barone [Italie] ; Carolina Ciacci [Italie] ; Luigi Ferini Strambi [Italie] ; Paolo Barone [Italie]Source :
- Movement Disorders [ 0885-3185 ] ; 2010-05-15.
English descriptors
Abstract
Restless legs syndrome (RLS) is a common neurological condition, frequently idiopathic, sometimes associated with specific disorders such as iron deficiency. We investigated RLS prevalence in celiac disease (CD), an autoimmune disease characterized by several features such as malabsorption‐related iron deficiency anemia and peripheral neuropathy. We screened a population of 100 adult CD patients for CD features, iron metabolism, clinical and neurological conditions, and enrolled 100 age‐ and sex‐matched controls in the general population. RLS was ascertained in CD patients and controls by both the presence of the four essential International RLS Study Group diagnostic criteria and neurological examination. The International RLS Study Group rating scale was used to measure RLS severity. We found a 31% prevalence of RLS in the CD population that was significantly higher than the prevalence in the control population (4%; P < 0.001). The average severity of RLS in CD population was moderate (17 ± 6.5). In the CD population, no significant correlation was found between RLS and either gluten‐free diet or iron metabolism, despite hemoglobin levels were significantly lower in CD patients with RLS than without RLS (P = 0.003). We found no correlation between RLS and other possible causes of secondary RLS, including signs of peripheral neuropathy, pregnancy, end‐stage renal disease, and pharmacological treatments.Our study broadens the spectrum of neurological disorders associated with CD and indicates that RLS should be sought for in all patients with CD. © 2010 Movement Disorder Society
Url:
DOI: 10.1002/mds.22903
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: Pour aller vers cette notice dans l'étape Curation :001791
Links to Exploration step
ISTEX:023298FEECBEBAD55BCC6FB3A5F776F0EC2388EELe document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Restless legs syndrome is a common feature of adult celiac disease</title><author><name sortKey="Moccia, Marcello" sort="Moccia, Marcello" uniqKey="Moccia M" first="Marcello" last="Moccia">Marcello Moccia</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurological Sciences, University Federico II and IDC Hermitage Capodimonte, Naples, Italy</mods:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurological Sciences, University Federico II and IDC Hermitage Capodimonte, Naples</wicri:regionArea></affiliation></author><author><name sortKey="Pellecchia, Maria Teresa" sort="Pellecchia, Maria Teresa" uniqKey="Pellecchia M" first="Maria Teresa" last="Pellecchia">Maria Teresa Pellecchia</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurological Sciences, University Federico II and IDC Hermitage Capodimonte, Naples, Italy</mods:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurological Sciences, University Federico II and IDC Hermitage Capodimonte, Naples</wicri:regionArea></affiliation></author><author><name sortKey="Erro, Roberto" sort="Erro, Roberto" uniqKey="Erro R" first="Roberto" last="Erro">Roberto Erro</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurological Sciences, University Federico II and IDC Hermitage Capodimonte, Naples, Italy</mods:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurological Sciences, University Federico II and IDC Hermitage Capodimonte, Naples</wicri:regionArea></affiliation></author><author><name sortKey="Zingone, Fabiana" sort="Zingone, Fabiana" uniqKey="Zingone F" first="Fabiana" last="Zingone">Fabiana Zingone</name><affiliation wicri:level="1"><mods:affiliation>Department of Systematic Pathology, University Federico II, Naples, Italy</mods:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Systematic Pathology, University Federico II, Naples</wicri:regionArea></affiliation></author><author><name sortKey="Marelli, Sara" sort="Marelli, Sara" uniqKey="Marelli S" first="Sara" last="Marelli">Sara Marelli</name><affiliation wicri:level="1"><mods:affiliation>Sleep Disorders Center, University Vita‐Salute San Raffaele, Milan, Italy</mods:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Sleep Disorders Center, University Vita‐Salute San Raffaele, Milan</wicri:regionArea></affiliation></author><author><name sortKey="Barone, Damiano Giuseppe" sort="Barone, Damiano Giuseppe" uniqKey="Barone D" first="Damiano Giuseppe" last="Barone">Damiano Giuseppe Barone</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurological Sciences, University Federico II and IDC Hermitage Capodimonte, Naples, Italy</mods:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurological Sciences, University Federico II and IDC Hermitage Capodimonte, Naples</wicri:regionArea></affiliation></author><author><name sortKey="Ciacci, Carolina" sort="Ciacci, Carolina" uniqKey="Ciacci C" first="Carolina" last="Ciacci">Carolina Ciacci</name><affiliation wicri:level="1"><mods:affiliation>Department of Systematic Pathology, University Federico II, Naples, Italy</mods:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Systematic Pathology, University Federico II, Naples</wicri:regionArea></affiliation></author><author><name sortKey="Strambi, Luigi Ferini" sort="Strambi, Luigi Ferini" uniqKey="Strambi L" first="Luigi Ferini" last="Strambi">Luigi Ferini Strambi</name><affiliation wicri:level="1"><mods:affiliation>Sleep Disorders Center, University Vita‐Salute San Raffaele, Milan, Italy</mods:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Sleep Disorders Center, University Vita‐Salute San Raffaele, Milan</wicri:regionArea></affiliation></author><author><name sortKey="Barone, Paolo" sort="Barone, Paolo" uniqKey="Barone P" first="Paolo" last="Barone">Paolo Barone</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurological Sciences, University Federico II and IDC Hermitage Capodimonte, Naples, Italy</mods:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurological Sciences, University Federico II and IDC Hermitage Capodimonte, Naples</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:023298FEECBEBAD55BCC6FB3A5F776F0EC2388EE</idno><date when="2010" year="2010">2010</date><idno type="doi">10.1002/mds.22903</idno><idno type="url">https://api.istex.fr/document/023298FEECBEBAD55BCC6FB3A5F776F0EC2388EE/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">001791</idno><idno type="wicri:Area/Istex/Curation">001791</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Restless legs syndrome is a common feature of adult celiac disease</title><author><name sortKey="Moccia, Marcello" sort="Moccia, Marcello" uniqKey="Moccia M" first="Marcello" last="Moccia">Marcello Moccia</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurological Sciences, University Federico II and IDC Hermitage Capodimonte, Naples, Italy</mods:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurological Sciences, University Federico II and IDC Hermitage Capodimonte, Naples</wicri:regionArea></affiliation></author><author><name sortKey="Pellecchia, Maria Teresa" sort="Pellecchia, Maria Teresa" uniqKey="Pellecchia M" first="Maria Teresa" last="Pellecchia">Maria Teresa Pellecchia</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurological Sciences, University Federico II and IDC Hermitage Capodimonte, Naples, Italy</mods:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurological Sciences, University Federico II and IDC Hermitage Capodimonte, Naples</wicri:regionArea></affiliation></author><author><name sortKey="Erro, Roberto" sort="Erro, Roberto" uniqKey="Erro R" first="Roberto" last="Erro">Roberto Erro</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurological Sciences, University Federico II and IDC Hermitage Capodimonte, Naples, Italy</mods:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurological Sciences, University Federico II and IDC Hermitage Capodimonte, Naples</wicri:regionArea></affiliation></author><author><name sortKey="Zingone, Fabiana" sort="Zingone, Fabiana" uniqKey="Zingone F" first="Fabiana" last="Zingone">Fabiana Zingone</name><affiliation wicri:level="1"><mods:affiliation>Department of Systematic Pathology, University Federico II, Naples, Italy</mods:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Systematic Pathology, University Federico II, Naples</wicri:regionArea></affiliation></author><author><name sortKey="Marelli, Sara" sort="Marelli, Sara" uniqKey="Marelli S" first="Sara" last="Marelli">Sara Marelli</name><affiliation wicri:level="1"><mods:affiliation>Sleep Disorders Center, University Vita‐Salute San Raffaele, Milan, Italy</mods:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Sleep Disorders Center, University Vita‐Salute San Raffaele, Milan</wicri:regionArea></affiliation></author><author><name sortKey="Barone, Damiano Giuseppe" sort="Barone, Damiano Giuseppe" uniqKey="Barone D" first="Damiano Giuseppe" last="Barone">Damiano Giuseppe Barone</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurological Sciences, University Federico II and IDC Hermitage Capodimonte, Naples, Italy</mods:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurological Sciences, University Federico II and IDC Hermitage Capodimonte, Naples</wicri:regionArea></affiliation></author><author><name sortKey="Ciacci, Carolina" sort="Ciacci, Carolina" uniqKey="Ciacci C" first="Carolina" last="Ciacci">Carolina Ciacci</name><affiliation wicri:level="1"><mods:affiliation>Department of Systematic Pathology, University Federico II, Naples, Italy</mods:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Systematic Pathology, University Federico II, Naples</wicri:regionArea></affiliation></author><author><name sortKey="Strambi, Luigi Ferini" sort="Strambi, Luigi Ferini" uniqKey="Strambi L" first="Luigi Ferini" last="Strambi">Luigi Ferini Strambi</name><affiliation wicri:level="1"><mods:affiliation>Sleep Disorders Center, University Vita‐Salute San Raffaele, Milan, Italy</mods:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Sleep Disorders Center, University Vita‐Salute San Raffaele, Milan</wicri:regionArea></affiliation></author><author><name sortKey="Barone, Paolo" sort="Barone, Paolo" uniqKey="Barone P" first="Paolo" last="Barone">Paolo Barone</name><affiliation wicri:level="1"><mods:affiliation>Department of Neurological Sciences, University Federico II and IDC Hermitage Capodimonte, Naples, Italy</mods:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Neurological Sciences, University Federico II and IDC Hermitage Capodimonte, Naples</wicri:regionArea></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2010-05-15">2010-05-15</date><biblScope unit="vol">25</biblScope><biblScope unit="issue">7</biblScope><biblScope unit="page" from="877">877</biblScope><biblScope unit="page" to="881">881</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">023298FEECBEBAD55BCC6FB3A5F776F0EC2388EE</idno><idno type="DOI">10.1002/mds.22903</idno><idno type="ArticleID">MDS22903</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>celiac disease</term><term>restless legs syndrome</term><term>sleep disorders</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Restless legs syndrome (RLS) is a common neurological condition, frequently idiopathic, sometimes associated with specific disorders such as iron deficiency. We investigated RLS prevalence in celiac disease (CD), an autoimmune disease characterized by several features such as malabsorption‐related iron deficiency anemia and peripheral neuropathy. We screened a population of 100 adult CD patients for CD features, iron metabolism, clinical and neurological conditions, and enrolled 100 age‐ and sex‐matched controls in the general population. RLS was ascertained in CD patients and controls by both the presence of the four essential International RLS Study Group diagnostic criteria and neurological examination. The International RLS Study Group rating scale was used to measure RLS severity. We found a 31% prevalence of RLS in the CD population that was significantly higher than the prevalence in the control population (4%; P < 0.001). The average severity of RLS in CD population was moderate (17 ± 6.5). In the CD population, no significant correlation was found between RLS and either gluten‐free diet or iron metabolism, despite hemoglobin levels were significantly lower in CD patients with RLS than without RLS (P = 0.003). We found no correlation between RLS and other possible causes of secondary RLS, including signs of peripheral neuropathy, pregnancy, end‐stage renal disease, and pharmacological treatments.Our study broadens the spectrum of neurological disorders associated with CD and indicates that RLS should be sought for in all patients with CD. © 2010 Movement Disorder Society</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Istex/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001791 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Curation/biblio.hfd -nk 001791 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= Istex
|étape= Curation
|type= RBID
|clé= ISTEX:023298FEECBEBAD55BCC6FB3A5F776F0EC2388EE
|texte= Restless legs syndrome is a common feature of adult celiac disease
}}
| This area was generated with Dilib version V0.6.23. |  |